SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fka'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		4 / 7 GLY C  89
GLY C  93
PHE C  58
PHE C  57
 None
 0.91A 2qwxA-5fkaC:
undetectable
2qwxB-5fkaC:
undetectable		 2qwxA-5fkaC:
21.37
2qwxB-5fkaC:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M8P_A_65BA562_0
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		5 / 11 LEU C 169
LYS C  15
TYR C 231
LEU C 198
TYR C 170
 None
 1.34A 3m8pA-5fkaC:
undetectable
3m8pB-5fkaC:
undetectable		 3m8pA-5fkaC:
19.15
3m8pB-5fkaC:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		4 / 7 TYR C  88
VAL C 185
VAL C 125
ILE C 219
 None
 1.30A 3ms9B-5fkaC:
undetectable		 3ms9B-5fkaC:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		5 / 12 LEU C 169
LYS C  15
TYR C 231
LEU C 198
TYR C 170
 None
 1.21A 5cymA-5fkaC:
undetectable		 5cymA-5fkaC:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		4 / 5 TYR C 205
GLN C  95
THR C 208
LEU C 209
 None
 1.35A 6d8pA-5fkaC:
undetectable		 6d8pA-5fkaC:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		5 / 12 LEU C 169
LYS C  15
TYR C 231
LEU C 198
TYR C 170
 None
 1.21A 6eliA-5fkaC:
undetectable		 6eliA-5fkaC:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		3 / 3 LEU C 163
LEU C 198
ARG C 160
 None
 0.58A 6fgcA-5fkaC:
undetectable		 6fgcA-5fkaC:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 5fka STAPHYLOCOCCAL
ENTEROTOXIN E
(Staphylococcus
aureus) 		3 / 3 LEU C 163
LEU C 198
ARG C 160
 None
 0.59A 6fgdA-5fkaC:
undetectable		 6fgdA-5fkaC:
21.30