SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fkr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 8 ASP A  70
VAL A 101
GLY A  72
GLY A  73
 None
 0.88A 1ekjE-5fkrA:
undetectable
1ekjF-5fkrA:
undetectable		 1ekjE-5fkrA:
14.93
1ekjF-5fkrA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_C_ESTC353_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 SER A 574
VAL A 552
TYR A 578
GLY A 572
VAL A 522
 None
 1.24A 1fduC-5fkrA:
undetectable		 1fduC-5fkrA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 TRP A  93
VAL A  91
TRP A  96
 None
 1.16A 1gmkC-5fkrA:
undetectable
1gmkD-5fkrA:
undetectable		 1gmkC-5fkrA:
2.40
1gmkD-5fkrA:
2.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4G_B_RIOB501_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 9 GLU A 416
GLY A 159
SER A 292
ASP A 293
ASP A 299
 None
 1.48A 1m4gB-5fkrA:
undetectable		 1m4gB-5fkrA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 9 GLY A 161
PRO A  53
GLY A 159
GLY A 152
GLY A 153
 None
 1.13A 1mxdA-5fkrA:
undetectable		 1mxdA-5fkrA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 11 GLY A 161
PRO A  53
GLY A 159
GLY A 152
GLY A 153
 None
 1.12A 1mxgA-5fkrA:
undetectable		 1mxgA-5fkrA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 4 GLY A 486
SER A 479
ILE A  46
HIS A 489
 None
 1.13A 1yajJ-5fkrA:
undetectable		 1yajJ-5fkrA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 5 LEU A 428
ILE A  55
SER A 417
GLY A 334
 None
 0.83A 2otfA-5fkrA:
undetectable		 2otfA-5fkrA:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 6 MET A 346
ILE A 451
ARG A 384
PRO A 320
 None
 1.38A 2qd3B-5fkrA:
undetectable		 2qd3B-5fkrA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 6 ILE A 173
PHE A 228
GLY A 260
GLY A 259
 None
 0.71A 2qx6A-5fkrA:
undetectable
2qx6B-5fkrA:
undetectable		 2qx6A-5fkrA:
14.45
2qx6B-5fkrA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 LEU A 759
GLY A 742
ILE A 740
VAL A 468
ASP A 743
 None
 0.94A 3bwcB-5fkrA:
undetectable		 3bwcB-5fkrA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 PHE A 675
LEU A 654
GLY A 615
ALA A 613
THR A 616
 None
 1.35A 3dh0A-5fkrA:
undetectable		 3dh0A-5fkrA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 ALA A 562
ARG A 603
LYS A 643
 None
 1.03A 3kp3B-5fkrA:
undetectable		 3kp3B-5fkrA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 6 VAL A 101
VAL A 114
ILE A  56
ARG A 757
 None
 1.07A 3pyyA-5fkrA:
undetectable		 3pyyA-5fkrA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 GLU A 416
GLY A 159
GLY A 157
LEU A 274
GLY A 161
 None
 1.07A 3sglA-5fkrA:
undetectable		 3sglA-5fkrA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		6 / 12 GLY A 331
GLY A 334
ALA A 348
PHE A 359
ALA A 357
ASP A 356
 None
 1.46A 3sudD-5fkrA:
undetectable		 3sudD-5fkrA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 GLY A 331
GLY A 334
ALA A 348
PHE A 359
ASP A 356
 None
 1.10A 3sugA-5fkrA:
undetectable		 3sugA-5fkrA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 5 LEU A 442
ARG A 361
ILE A 337
ARG A 339
 None
 1.36A 3ticA-5fkrA:
4.2		 3ticA-5fkrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 LEU A 395
ILE A  46
GLY A  50
ILE A 484
ARG A 757
 None
 1.04A 3uj6A-5fkrA:
undetectable		 3uj6A-5fkrA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 7 ALA A 247
ARG A 163
HIS A 276
GLY A 295
 None
 0.89A 3v4tH-5fkrA:
undetectable		 3v4tH-5fkrA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 5 ASP A 602
GLU A 515
GLY A 647
GLU A 649
 None
 1.38A 3w9tA-5fkrA:
undetectable		 3w9tA-5fkrA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 9 GLY A 153
GLY A 152
ASN A 123
GLY A 100
TYR A 121
 None
 1.07A 3ztvA-5fkrA:
undetectable		 3ztvA-5fkrA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 VAL A 465
ILE A 740
VAL A 713
ILE A 726
LEU A 759
 None
 1.25A 4a84A-5fkrA:
undetectable		 4a84A-5fkrA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 6 THR A 435
GLY A  49
ILE A  46
LEU A 460
 None
 1.21A 4acaC-5fkrA:
undetectable		 4acaC-5fkrA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 PHE A 714
ASP A 685
ARG A 711
 None
 0.84A 4eahF-5fkrA:
undetectable		 4eahF-5fkrA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 PHE A 714
ASP A 685
ARG A 711
 None
 0.84A 4eahG-5fkrA:
undetectable		 4eahG-5fkrA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 6 GLU A 461
ILE A 484
THR A 463
HIS A 489
 None
 1.27A 4qwpA-5fkrA:
undetectable		 4qwpA-5fkrA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 GLY A 295
GLY A 296
ILE A 289
TYR A 206
GLN A 269
 None
 0.87A 4rtmA-5fkrA:
undetectable		 4rtmA-5fkrA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 7 THR A  69
GLY A  54
ALA A  67
ILE A 436
 None
 0.95A 4txnC-5fkrA:
undetectable		 4txnC-5fkrA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 THR A 432
GLY A  48
GLY A  50
TRP A 413
THR A 497
 None
 1.06A 4uckB-5fkrA:
undetectable		 4uckB-5fkrA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 7 SER A 135
ASP A  89
ARG A 757
GLY A  73
 None
 1.09A 5btfA-5fkrA:
undetectable
5btfC-5fkrA:
undetectable
5btfD-5fkrA:
undetectable		 5btfA-5fkrA:
21.17
5btfC-5fkrA:
21.17
5btfD-5fkrA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 7 SER A 292
GLY A 222
THR A 122
GLU A 179
 None
 1.12A 5btfA-5fkrA:
undetectable
5btfC-5fkrA:
undetectable
5btfD-5fkrA:
undetectable		 5btfA-5fkrA:
21.17
5btfC-5fkrA:
21.17
5btfD-5fkrA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 GLY A 756
LEU A 481
THR A 754
GLY A 753
GLY A  92
 None
 0.98A 5d4uA-5fkrA:
undetectable		 5d4uA-5fkrA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 GLY A 756
LEU A 481
THR A 754
GLY A 753
GLY A  92
 None
 0.99A 5d4uB-5fkrA:
undetectable		 5d4uB-5fkrA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 GLY A 756
LEU A 481
THR A 754
GLY A 753
GLY A  92
 None
 0.96A 5d4uC-5fkrA:
undetectable		 5d4uC-5fkrA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 GLY A 756
LEU A 481
THR A 754
GLY A 753
GLY A  92
 None
 0.96A 5d4uD-5fkrA:
undetectable		 5d4uD-5fkrA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 THR A 688
SER A 741
ASP A 512
 None
 0.70A 5kvaA-5fkrA:
undetectable		 5kvaA-5fkrA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 THR A 688
SER A 741
ASP A 512
 None
 0.71A 5kvaB-5fkrA:
undetectable		 5kvaB-5fkrA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 8 PRO A 455
TYR A 437
SER A 400
ASN A 396
 None
 1.07A 5l1fA-5fkrA:
undetectable
5l1fB-5fkrA:
undetectable		 5l1fA-5fkrA:
22.75
5l1fB-5fkrA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		4 / 6 ASP A 110
ARG A 170
ASN A 237
ASN A 171
 None
 1.13A 5l6eA-5fkrA:
undetectable		 5l6eA-5fkrA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 ARG A  45
ASN A  43
THR A  69
GLY A 756
THR A 463
 None
 1.40A 5oj0A-5fkrA:
undetectable		 5oj0A-5fkrA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 LEU A  87
LEU A  88
GLY A  73
GLY A  72
LEU A 104
 None
 1.09A 5uc1A-5fkrA:
undetectable		 5uc1A-5fkrA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 LEU A  87
LEU A  88
GLY A  73
GLY A  72
LEU A 104
 None
 1.09A 5uc1B-5fkrA:
undetectable		 5uc1B-5fkrA:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 ILE A  46
LEU A 395
VAL A 392
ALA A  67
TYR A  75
 None
 1.06A 5uxdB-5fkrA:
2.9		 5uxdB-5fkrA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		5 / 12 LEU A 593
VAL A 577
PHE A 617
PHE A 642
ALA A 644
 None
 1.04A 5uxdB-5fkrA:
2.9		 5uxdB-5fkrA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 TYR A 115
ARG A 134
THR A 136
 None
 0.91A 5z84J-5fkrA:
undetectable		 5z84J-5fkrA:
6.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 5fkr ENDO-1,4-BETA-GLUCAN
ASE/XYLOGLUCANASE,
PUTATIVE, GLY74A
(Cellvibrio
japonicus) 		3 / 3 VAL A 279
TYR A 288
GLU A 419
 None
 0.94A 5zmqD-5fkrA:
undetectable
5zmqE-5fkrA:
undetectable		 5zmqD-5fkrA:
14.41
5zmqE-5fkrA:
6.83