SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fkw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		5 / 11 GLU D 110
ILE D  30
THR D  16
LEU D 113
GLY D  27
 None
 1.42A 1i7qA-5fkwD:
undetectable		 1i7qA-5fkwD:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		4 / 7 LEU D 171
VAL D 174
THR D 179
VAL D 133
 None
 1.07A 2zaxA-5fkwD:
undetectable		 2zaxA-5fkwD:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		4 / 7 LEU D 171
VAL D 174
THR D 179
VAL D 133
 None
 1.06A 3fwgB-5fkwD:
undetectable		 3fwgB-5fkwD:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		4 / 7 LEU D 171
VAL D 174
THR D 179
VAL D 133
 None
 1.04A 3fwiA-5fkwD:
undetectable		 3fwiA-5fkwD:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		4 / 7 THR D 121
ILE D  90
LEU D  11
PHE D  86
 None
 0.73A 4ejjD-5fkwD:
undetectable		 4ejjD-5fkwD:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		5 / 9 ILE D  90
PHE D  86
ILE D   9
ALA D  93
ARG D   7
 None
 1.21A 4yp2B-5fkwD:
undetectable		 4yp2B-5fkwD:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		5 / 9 ILE D  90
PHE D  86
ILE D   9
ALA D  93
ARG D   7
 None
 1.19A 5cf9B-5fkwD:
undetectable		 5cf9B-5fkwD:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		5 / 9 ILE D  90
PHE D  86
ILE D   9
GLU D  37
ARG D   7
 None
 1.39A 5cf9B-5fkwD:
undetectable		 5cf9B-5fkwD:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 5fkw DNA POLYMERASE III
EPSILON
(Escherichia
coli) 		4 / 4 ILE D 170
ILE D 154
ARG D 159
LEU D 171
 None
 1.39A 5dzkh-5fkwD:
undetectable
5dzkn-5fkwD:
undetectable
5dzkv-5fkwD:
undetectable		 5dzkh-5fkwD:
23.32
5dzkn-5fkwD:
23.32
5dzkv-5fkwD:
1.20