SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5flw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		5 / 12 PHE A  56
ILE A  23
LEU A  25
VAL A 249
VAL A 248
 None
 1.03A 3rukB-5flwA:
undetectable		 3rukB-5flwA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		4 / 5 LEU A  66
PHE A 123
PRO A 122
ALA A 116
 None
 1.16A 3vm4A-5flwA:
undetectable		 3vm4A-5flwA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		3 / 3 ASP A 167
TRP A 131
SER A 148
 None
 0.97A 4lrhA-5flwA:
undetectable		 4lrhA-5flwA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		5 / 12 ILE A 172
VAL A 113
GLU A  82
VAL A  96
GLY A  24
 None
 0.91A 5igjA-5flwA:
undetectable		 5igjA-5flwA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		5 / 12 ILE A 172
VAL A 113
GLU A  82
VAL A  96
GLY A  24
 None
 0.91A 5igpA-5flwA:
1.8		 5igpA-5flwA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		5 / 12 ILE A 172
VAL A 113
GLU A  82
VAL A  96
GLY A  24
 None
 0.92A 5igtA-5flwA:
1.9		 5igtA-5flwA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		4 / 6 TYR A 256
ILE A 193
TYR A 150
TYR A 169
 None
 1.33A 5igyA-5flwA:
undetectable		 5igyA-5flwA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		5 / 11 SER A 295
ASP A 296
THR A 297
PRO A 235
LEU A 292
 None
 1.40A 5jh7B-5flwA:
undetectable		 5jh7B-5flwA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		5 / 11 SER A 295
ASP A 296
THR A 297
PRO A 235
LEU A 292
 None
 1.42A 5jh7D-5flwA:
undetectable		 5jh7D-5flwA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 219
SER A 218
TYR A 217
 None
 0.79A 5jsdA-5flwA:
undetectable		 5jsdA-5flwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 219
SER A 218
TYR A 217
 None
 0.80A 5jsdB-5flwA:
undetectable		 5jsdB-5flwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 219
SER A 218
TYR A 217
 None
 0.79A 5jsdC-5flwA:
undetectable		 5jsdC-5flwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 219
SER A 218
TYR A 217
 None
 0.79A 5jseA-5flwA:
undetectable		 5jseA-5flwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 219
SER A 218
TYR A 217
 None
 0.78A 5jseB-5flwA:
undetectable		 5jseB-5flwA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 5flw EXO-BETA-1,3-GALACTA
NASE
(Bifidobacterium
bifidum) 		3 / 3 THR A 219
SER A 218
TYR A 217
 None
 0.78A 5jseC-5flwA:
undetectable		 5jseC-5flwA:
18.31