SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fm5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5fm5 MYOMESIN-1
OBSCURIN-LIKE-1
(Homo
sapiens) 		5 / 12 ILE O 248
VAL M 551
ALA M 604
ILE M 526
ILE M 528
 None
 0.96A 1epbB-5fm5O:
undetectable		 1epbB-5fm5O:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 5fm5 MYOMESIN-1
OBSCURIN-LIKE-1
(Homo
sapiens) 		5 / 12 LEU M 574
SER M 557
CYH M 559
LEU O 329
LEU O 249
 None
 1.38A 2zlcA-5fm5M:
undetectable		 2zlcA-5fm5M:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm5 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE M 528
VAL M 516
SER M 599
ILE M 581
TRP M 556
 None
 0.95A 3uprA-5fm5M:
undetectable		 3uprA-5fm5M:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm5 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE M 528
VAL M 516
SER M 599
ILE M 581
TRP M 556
 None
 0.95A 3uprC-5fm5M:
3.9		 3uprC-5fm5M:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5fm5 MYOMESIN-1
(Homo
sapiens) 		5 / 12 ILE M 528
VAL M 516
SER M 599
ILE M 581
TRP M 556
 None
 0.99A 3vrjA-5fm5M:
4.1
3vrjC-5fm5M:
undetectable		 3vrjA-5fm5M:
22.50
3vrjC-5fm5M:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 5fm5 MYOMESIN-1
OBSCURIN-LIKE-1
(Homo
sapiens;
Homo
sapiens) 		4 / 5 GLY M 552
THR M 553
HIS O 280
GLY O 283
 None
 0.93A 4v20A-5fm5M:
undetectable		 4v20A-5fm5M:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 5fm5 OBSCURIN-LIKE-1
(Homo
sapiens) 		4 / 6 GLU O 282
GLY O 315
ARG O 314
ARG O 292
 None
 1.32A 5jcnB-5fm5O:
undetectable		 5jcnB-5fm5O:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 5fm5 OBSCURIN-LIKE-1
(Homo
sapiens) 		3 / 3 ARG O 296
PRO O 275
TYR O 268
 None
 1.00A 5tzoB-5fm5O:
undetectable		 5tzoB-5fm5O:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm5 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE M 528
VAL M 516
SER M 599
ILE M 581
TRP M 556
 None
 0.94A 5u98A-5fm5M:
3.8		 5u98A-5fm5M:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm5 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE M 528
VAL M 516
SER M 599
ILE M 581
TRP M 556
 None
 0.96A 5u98D-5fm5M:
4.1		 5u98D-5fm5M:
21.38