SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fm8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 5fm8 MYOMESIN-1
(Homo
sapiens) 		5 / 10 PRO A 513
ASN A 588
GLY A 543
TYR A 544
ALA A 511
 None
 1.38A 3pp7B-5fm8A:
undetectable		 3pp7B-5fm8A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm8 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE A 528
VAL A 516
SER A 599
ILE A 581
TRP A 556
 None
 0.98A 3uprA-5fm8A:
3.8		 3uprA-5fm8A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm8 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE A 528
VAL A 516
SER A 599
ILE A 581
TRP A 556
 None
 0.97A 3uprC-5fm8A:
3.7		 3uprC-5fm8A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5fm8 MYOMESIN-1
(Homo
sapiens) 		5 / 12 ILE A 528
VAL A 516
SER A 599
ILE A 581
TRP A 556
 None
 1.02A 3vrjA-5fm8A:
3.6
3vrjC-5fm8A:
undetectable		 3vrjA-5fm8A:
15.48
3vrjC-5fm8A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm8 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE A 528
VAL A 516
SER A 599
ILE A 581
TRP A 556
 None
 0.96A 5u98A-5fm8A:
3.7		 5u98A-5fm8A:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 5fm8 MYOMESIN-1
(Homo
sapiens) 		5 / 10 ILE A 528
VAL A 516
SER A 599
ILE A 581
TRP A 556
 None
 0.99A 5u98D-5fm8A:
3.8		 5u98D-5fm8A:
15.48