SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5fma NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens) 		4 / 8 ASN A 264
THR A 293
GLN A 290
GLY A 289
 None
 1.00A 5nzxA-5fmaA:
undetectable		 5nzxA-5fmaA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5fma NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens) 		3 / 3 HIS A 171
GLU A 181
ASN A 197
 None
CA  A1295 (-2.9A)
CA  A1295 (-3.0A)
 1.00A 5wbvA-5fmaA:
undetectable		 5wbvA-5fmaA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 5fma NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens) 		3 / 3 HIS A 171
GLU A 181
ASN A 197
 None
CA  A1295 (-2.9A)
CA  A1295 (-3.0A)
 1.01A 5wbvB-5fmaA:
undetectable		 5wbvB-5fmaA:
22.38