SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 5fmg PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 TYR F 116
PHE F 128
ILE F  72
GLY F  76
 None
 0.94A 11gsA-5fmgF:
undetectable		 11gsA-5fmgF:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		4 / 8 HIS C 149
THR C 162
GLY C 158
LEU C 135
 None
 0.77A 1aegA-5fmgC:
undetectable		 1aegA-5fmgC:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 5fmg PROTEASOME COMPONENT
C8, PUTATIVE
(Plasmodium
falciparum) 		4 / 6 VAL G  72
ASN G  73
ILE G 221
ASN G  75
 None
 0.96A 1e06A-5fmgG:
undetectable		 1e06A-5fmgG:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 LEU K 151
THR K 152
GLY K   9
LEU K   7
 None
 0.84A 1gtiB-5fmgK:
undetectable		 1gtiB-5fmgK:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 CYH I  31
HIS I 185
LEU I  34
ALA I  44
LEU I  14
 7F1  I 300 ( 3.8A)
None
None
None
None
 1.48A 1hwiA-5fmgI:
1.1		 1hwiA-5fmgI:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_2
(HMG-COA REDUCTASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 CYH I  31
HIS I 185
LEU I  34
ALA I  44
LEU I  14
 7F1  I 300 ( 3.8A)
None
None
None
None
 1.48A 1hwkB-5fmgI:
1.0		 1hwkB-5fmgI:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_B_117B1_1
(HMG-COA REDUCTASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 CYH I  31
HIS I 185
LEU I  34
ALA I  44
LEU I  14
 7F1  I 300 ( 3.8A)
None
None
None
None
 1.48A 1hwkA-5fmgI:
1.1		 1hwkA-5fmgI:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_2
(HMG-COA REDUCTASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 CYH I  31
HIS I 185
LEU I  34
ALA I  44
LEU I  14
 7F1  I 300 ( 3.8A)
None
None
None
None
 1.46A 1hwkD-5fmgI:
undetectable		 1hwkD-5fmgI:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_1
(HMG-COA REDUCTASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 CYH I  31
HIS I 185
LEU I  34
ALA I  44
LEU I  14
 7F1  I 300 ( 3.8A)
None
None
None
None
 1.47A 1hwkC-5fmgI:
1.5		 1hwkC-5fmgI:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 GLY K   6
VAL K 127
LEU K 115
LEU K 143
HIS K 132
 None
 0.98A 1mx1A-5fmgK:
undetectable		 1mx1A-5fmgK:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 GLY K   6
VAL K 127
LEU K 115
LEU K 143
HIS K 132
 None
 0.85A 1mx1F-5fmgK:
undetectable		 1mx1F-5fmgK:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		4 / 6 PHE D  40
ALA D  41
ILE D  35
SER D  37
 None
 0.94A 1sbrA-5fmgD:
undetectable
1sbrB-5fmgD:
undetectable		 1sbrA-5fmgD:
21.66
1sbrB-5fmgD:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 ILE I 178
CYH I 176
TYR I 142
GLY I  15
LEU I 110
 None
 0.98A 2bxeB-5fmgI:
undetectable		 2bxeB-5fmgI:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 5fmg PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ILE F  70
CYH F  92
LEU F  84
VAL F 112
LEU F 132
 None
 1.20A 2bxfA-5fmgF:
undetectable		 2bxfA-5fmgF:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA C 163
LEU C 191
SER C 172
LEU C 175
LEU C  37
 None
 1.00A 2ceoA-5fmgC:
undetectable		 2ceoA-5fmgC:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 5fmg PROTEASOME COMPONENT
C8, PUTATIVE
PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE
(Plasmodium
falciparum) 		4 / 8 TYR F  13
GLY G  85
ALA G 135
ALA G 136
 None
 0.59A 2ej3A-5fmgF:
undetectable		 2ej3A-5fmgF:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  27
LYS I  33
GLY I  47
ALA I  49
SER I 169
 7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
None
 1.23A 2f162-5fmgI:
28.2		 2f162-5fmgI:
27.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.52A 2f162-5fmgI:
28.2		 2f162-5fmgI:
27.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.86A 2f162-5fmgI:
28.2		 2f162-5fmgI:
27.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 ALA I  27
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.06A 2f16H-5fmgI:
30.1
2f16I-5fmgI:
26.5		 2f16H-5fmgI:
48.70
2f16I-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  27
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.82A 2f16H-5fmgI:
30.1
2f16I-5fmgI:
26.5		 2f16H-5fmgI:
48.70
2f16I-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.03A 2f16K-5fmgI:
27.9
2f16L-5fmgI:
23.8		 2f16K-5fmgI:
26.29
2f16L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 2f16K-5fmgI:
27.9
2f16L-5fmgI:
23.8		 2f16K-5fmgI:
26.29
2f16L-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
VAL L  31
GLY L  47
ALA L  49
 None
 0.76A 2f16K-5fmgL:
28.3
2f16L-5fmgL:
23.8		 2f16K-5fmgL:
47.89
2f16L-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.51A 2f16N-5fmgI:
28.2		 2f16N-5fmgI:
27.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.86A 2f16N-5fmgI:
28.2		 2f16N-5fmgI:
27.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 ALA I  27
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.06A 2f16V-5fmgI:
30.1
2f16W-5fmgI:
26.5		 2f16V-5fmgI:
48.70
2f16W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  27
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.83A 2f16V-5fmgI:
30.1
2f16W-5fmgI:
26.5		 2f16V-5fmgI:
48.70
2f16W-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.04A 2f16Y-5fmgI:
16.7
2f16Z-5fmgI:
23.5		 2f16Y-5fmgI:
26.29
2f16Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 2f16Y-5fmgI:
16.7
2f16Z-5fmgI:
23.5		 2f16Y-5fmgI:
26.29
2f16Z-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
VAL L  31
GLY L  47
ALA L  49
 None
 0.76A 2f16Y-5fmgL:
16.5
2f16Z-5fmgL:
7.1		 2f16Y-5fmgL:
47.89
2f16Z-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.87A 2f80B-5fmgH:
undetectable		 2f80B-5fmgH:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 1.01A 2f81A-5fmgH:
undetectable		 2f81A-5fmgH:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.04A 2feuA-5fmgB:
undetectable		 2feuA-5fmgB:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 9 LEU C 135
VAL C  76
ASP C 151
ILE C  28
VAL C 132
 None
 1.43A 2l8mA-5fmgC:
undetectable		 2l8mA-5fmgC:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.83A 2o4sA-5fmgH:
undetectable		 2o4sA-5fmgH:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.90A 2pynA-5fmgH:
undetectable		 2pynA-5fmgH:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 9 ALA E 221
GLY E  39
ILE E  40
VAL E 148
ILE E 222
 None
 1.10A 2q5kA-5fmgE:
undetectable		 2q5kA-5fmgE:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 9 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.94A 2q5kA-5fmgH:
undetectable		 2q5kA-5fmgH:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 6 ILE M 123
PRO M 111
LEU M  74
ILE M 116
 None
 0.84A 2q83B-5fmgM:
undetectable		 2q83B-5fmgM:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 11 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.88A 2qhcA-5fmgH:
undetectable		 2qhcA-5fmgH:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		4 / 8 ASP E  84
PHE E 139
PHE D  10
ALA E  30
 None
 1.17A 2v7uA-5fmgE:
undetectable		 2v7uA-5fmgE:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA C 163
LEU C 191
SER C 172
LEU C 175
LEU C  37
 None
 1.03A 2xn7A-5fmgC:
undetectable
2xn7B-5fmgC:
undetectable		 2xn7A-5fmgC:
21.85
2xn7B-5fmgC:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5fmg PROTEASOME SUBUNIT
ALPHA, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 THR A  35
GLY A  88
GLY A 175
PRO A 162
ILE A 174
 None
 1.32A 2y7kC-5fmgA:
undetectable		 2y7kC-5fmgA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5fmg PROTEASOME SUBUNIT
ALPHA, PUTATIVE
(Plasmodium
falciparum) 		5 / 10 THR A  35
GLY A  88
GLY A 175
PRO A 162
ILE A 174
 None
 1.26A 2y7wB-5fmgA:
undetectable		 2y7wB-5fmgA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_1
(HYPOTHETICAL PROTEIN)		 5fmg PROTEASOME COMPONENT
C8, PUTATIVE
(Plasmodium
falciparum) 		4 / 4 GLY G 149
GLU G  41
ASP G  44
TYR G 227
 None
 1.43A 2yvlC-5fmgG:
undetectable		 2yvlC-5fmgG:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.86A 2z54A-5fmgH:
undetectable		 2z54A-5fmgH:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.87A 2z54B-5fmgH:
undetectable		 2z54B-5fmgH:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.08A 2zuhA-5fmgB:
undetectable		 2zuhA-5fmgB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.07A 2zuiA-5fmgB:
undetectable		 2zuiA-5fmgB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.04A 2zwtA-5fmgB:
undetectable		 2zwtA-5fmgB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.04A 2zwuA-5fmgB:
undetectable		 2zwuA-5fmgB:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 LEU B 134
GLN B 148
LEU B  86
PHE B 130
 None
 0.98A 2zxwP-5fmgB:
undetectable
2zxwW-5fmgB:
undetectable		 2zxwP-5fmgB:
18.82
2zxwW-5fmgB:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fmg PROTEASOME COMPONENT
C8, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ILE G 151
CYH G 153
SER G 137
ALA G 136
ILE G  31
 None
 1.15A 3adsB-5fmgG:
undetectable		 3adsB-5fmgG:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 LEU B 134
GLN B 148
LEU B  86
PHE B 130
 None
 0.98A 3ag1C-5fmgB:
undetectable
3ag1J-5fmgB:
undetectable		 3ag1C-5fmgB:
18.82
3ag1J-5fmgB:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 4 SER I 129
GLY I 130
GLY I 168
GLY I 170
 7F1  I 300 (-4.0A)
None
None
None
 0.91A 3bogB-5fmgI:
undetectable
3bogD-5fmgI:
undetectable		 3bogB-5fmgI:
undetectable
3bogD-5fmgI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 5fmg PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE
(Plasmodium
falciparum) 		5 / 9 TYR F 116
PHE F 128
VAL F 130
GLY F 131
ILE F  72
 None
 1.28A 3csjB-5fmgF:
undetectable		 3csjB-5fmgF:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.90A 3cywB-5fmgH:
undetectable		 3cywB-5fmgH:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.94A 3d20B-5fmgH:
undetectable		 3d20B-5fmgH:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 8 GLY M  37
GLY M  38
ILE M  41
SER M 168
 None
 0.66A 3d41A-5fmgM:
undetectable		 3d41A-5fmgM:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 5fmg PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE
(Plasmodium
falciparum) 		3 / 3 GLU F 172
SER F 159
VAL F  36
 None
 0.78A 3eeoA-5fmgF:
undetectable		 3eeoA-5fmgF:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 GLY M  42
ILE M 173
GLY M 169
LEU M  43
THR M 216
 None
 1.15A 3eeyC-5fmgM:
undetectable		 3eeyC-5fmgM:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		5 / 12 PHE C 134
ILE C 136
ASN D  77
VAL D  82
THR C 122
 None
 1.28A 3em0B-5fmgC:
undetectable		 3em0B-5fmgC:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I 158
LEU I 138
ALA I 134
ILE I 178
CYH I 176
 None
 1.02A 3fc6A-5fmgI:
undetectable		 3fc6A-5fmgI:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 ILE M  41
ILE M  50
ILE M 225
ALA M  53
LEU M 221
 None
 0.95A 3fpjA-5fmgM:
undetectable		 3fpjA-5fmgM:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.01A 3fwfB-5fmgB:
undetectable		 3fwfB-5fmgB:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.04A 3fwjA-5fmgB:
undetectable		 3fwjA-5fmgB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.87A 3jvyB-5fmgH:
undetectable		 3jvyB-5fmgH:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5fmg PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE
(Plasmodium
falciparum) 		5 / 10 TYR F 116
PHE F 128
VAL F 130
GLY F 131
ILE F  72
 None
 1.30A 3km6A-5fmgF:
undetectable		 3km6A-5fmgF:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.01A 3l63A-5fmgB:
undetectable		 3l63A-5fmgB:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.95A 3lzsA-5fmgH:
undetectable		 3lzsA-5fmgH:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 1.00A 3lzsB-5fmgH:
undetectable		 3lzsB-5fmgH:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.98A 3lzuA-5fmgH:
undetectable		 3lzuA-5fmgH:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.88A 3mg02-5fmgI:
28.1
3mg0V-5fmgI:
30.2		 3mg02-5fmgI:
27.71
3mg0V-5fmgI:
48.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 THR H  20
SER H  46
GLY H  47
HIS I 114
SER I 118
 None
 0.85A 3mg02-5fmgH:
28.5
3mg0V-5fmgH:
27.5		 3mg02-5fmgH:
27.38
3mg0V-5fmgH:
22.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.06A 3mg0H-5fmgI:
30.2
3mg0I-5fmgI:
26.4		 3mg0H-5fmgI:
48.70
3mg0I-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
THR I  21
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.90A 3mg0H-5fmgI:
30.2
3mg0I-5fmgI:
26.4		 3mg0H-5fmgI:
48.70
3mg0I-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
ALA I  46
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 0.99A 3mg0K-5fmgI:
27.9
3mg0L-5fmgI:
23.8		 3mg0K-5fmgI:
26.29
3mg0L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
ALA I  46
GLY I  47
SER I 129
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-4.0A)
7F1  I 300 (-2.6A)
 0.94A 3mg0K-5fmgI:
27.9
3mg0L-5fmgI:
23.8		 3mg0K-5fmgI:
26.29
3mg0L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.74A 3mg0K-5fmgI:
27.9
3mg0L-5fmgI:
23.8		 3mg0K-5fmgI:
26.29
3mg0L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
ALA I  46
GLY I  47
ALA I  49
SER I 129
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-4.0A)
 0.68A 3mg0K-5fmgI:
27.9
3mg0L-5fmgI:
23.8		 3mg0K-5fmgI:
26.29
3mg0L-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR L   1
ALA L  20
VAL L  31
ALA L  46
GLY L  47
ALA L  49
SER L 130
 None
 0.74A 3mg0K-5fmgL:
28.4
3mg0L-5fmgL:
23.9		 3mg0K-5fmgL:
47.89
3mg0L-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.53A 3mg0N-5fmgI:
28.1		 3mg0N-5fmgI:
27.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.86A 3mg0N-5fmgI:
28.1		 3mg0N-5fmgI:
27.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 ALA I  27
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.08A 3mg0V-5fmgI:
30.2
3mg0W-5fmgI:
26.5		 3mg0V-5fmgI:
48.70
3mg0W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  27
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.87A 3mg0V-5fmgI:
30.2
3mg0W-5fmgI:
26.5		 3mg0V-5fmgI:
48.70
3mg0W-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 12 ALA I  20
THR I  21
ALA I  27
LYS I  33
ALA I  46
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 0.99A 3mg0Y-5fmgI:
16.7
3mg0Z-5fmgI:
23.3		 3mg0Y-5fmgI:
26.29
3mg0Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		8 / 12 THR I   1
ALA I  20
THR I  21
ALA I  27
ALA I  46
GLY I  47
SER I 129
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-4.0A)
7F1  I 300 (-2.6A)
 0.92A 3mg0Y-5fmgI:
16.7
3mg0Z-5fmgI:
23.3		 3mg0Y-5fmgI:
26.29
3mg0Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 12 ALA I  20
THR I  21
ALA I  27
LYS I  33
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.73A 3mg0Y-5fmgI:
16.7
3mg0Z-5fmgI:
23.3		 3mg0Y-5fmgI:
26.29
3mg0Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		8 / 12 THR I   1
ALA I  20
THR I  21
ALA I  27
ALA I  46
GLY I  47
ALA I  49
SER I 129
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-4.0A)
 0.64A 3mg0Y-5fmgI:
16.7
3mg0Z-5fmgI:
23.3		 3mg0Y-5fmgI:
26.29
3mg0Z-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 12 THR L   1
ALA L  20
VAL L  31
ALA L  46
GLY L  47
ALA L  49
SER L 130
 None
 0.76A 3mg0Y-5fmgL:
16.5
3mg0Z-5fmgL:
8.4		 3mg0Y-5fmgL:
47.89
3mg0Z-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 VAL L  16
ALA L  15
PHE L 126
THR L  44
ILE L  34
 None
 1.31A 3n23A-5fmgL:
undetectable		 3n23A-5fmgL:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.88A 3ndtD-5fmgH:
undetectable		 3ndtD-5fmgH:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.84A 3ndwA-5fmgH:
undetectable		 3ndwA-5fmgH:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 6 ALA L 135
ILE L 138
HIS L 162
ASN L 158
 None
 1.16A 3nneG-5fmgL:
undetectable		 3nneG-5fmgL:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.86A 3oxcA-5fmgH:
undetectable		 3oxcA-5fmgH:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 GLY N 117
ILE N 176
GLY N  53
ILE N  43
ILE N  15
 None
 0.83A 3s53A-5fmgN:
undetectable		 3s53A-5fmgN:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 GLY N 117
ILE N 176
GLY N  53
ILE N  43
ILE N  15
 None
 0.94A 3s56A-5fmgN:
undetectable		 3s56A-5fmgN:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_2
(PROTEASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		5 / 9 LEU B  87
GLY B 211
ILE B 221
ILE B  68
ILE B  74
 None
 1.11A 3s56B-5fmgB:
undetectable		 3s56B-5fmgB:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 THR H  87
THR H  86
ILE H  82
LEU H 151
ILE H  56
 None
 1.00A 3sp9A-5fmgH:
undetectable		 3sp9A-5fmgH:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.97A 3tkwA-5fmgH:
undetectable		 3tkwA-5fmgH:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 ILE M 206
GLY M  38
CYH M 165
ILE M  41
ARG M  56
 None
 1.12A 3uj7A-5fmgM:
undetectable		 3uj7A-5fmgM:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.04A 3wrjA-5fmgB:
undetectable		 3wrjA-5fmgB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.03A 3wrlA-5fmgB:
undetectable		 3wrlA-5fmgB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.02A 3wrlE-5fmgB:
undetectable		 3wrlE-5fmgB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 7 THR B 161
LEU B 135
VAL B  75
VAL B  29
 None
 1.01A 3wrmA-5fmgB:
undetectable		 3wrmA-5fmgB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 8 VAL N  51
TYR N 160
VAL N 234
ILE N  21
 None
 1.05A 4aftD-5fmgN:
undetectable
4aftE-5fmgN:
undetectable		 4aftD-5fmgN:
17.28
4aftE-5fmgN:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DT8_B_ADNB401_1
(APH(2'')-ID)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 GLY N  53
ILE N  23
ILE N 206
LEU N 210
ILE N  13
 None
 1.10A 4dt8B-5fmgN:
undetectable		 4dt8B-5fmgN:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 VAL N  51
THR N  87
PRO N  88
ASN N  72
ILE N  73
 None
 1.35A 4eb6B-5fmgN:
undetectable
4eb6C-5fmgN:
undetectable		 4eb6B-5fmgN:
19.73
4eb6C-5fmgN:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5fmg PROTEASOME SUBUNIT
ALPHA, PUTATIVE
(Plasmodium
falciparum) 		3 / 3 LYS A   9
TYR A  23
ARG A  11
 None
 1.44A 4gc9A-5fmgA:
undetectable		 4gc9A-5fmgA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		3 / 4 SER K  24
GLY L  47
GLU L  56
 None
 0.62A 4juoA-5fmgK:
undetectable
4juoC-5fmgK:
undetectable		 4juoA-5fmgK:
18.24
4juoC-5fmgK:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 9 TYR E 103
PHE M 103
HIS M 107
ILE M 123
 None
 1.29A 4jvlA-5fmgE:
undetectable		 4jvlA-5fmgE:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_A_20JA601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 8 ASP M 213
SER M 168
SER M  58
ARG M  56
 None
 0.98A 4lv9A-5fmgM:
undetectable
4lv9B-5fmgM:
undetectable		 4lv9A-5fmgM:
21.23
4lv9B-5fmgM:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 ASP L 167
SER L 130
SER L  21
ARG L  19
 None
 1.26A 4lv9A-5fmgL:
undetectable
4lv9B-5fmgL:
undetectable		 4lv9A-5fmgL:
17.42
4lv9B-5fmgL:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB601_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 ASP M 213
SER M 168
SER M  58
ARG M  56
 None
 0.96A 4lv9A-5fmgM:
undetectable
4lv9B-5fmgM:
undetectable		 4lv9A-5fmgM:
21.23
4lv9B-5fmgM:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 LEU L 125
LEU L   4
ALA L 135
ASN L 158
ILE L  13
ALA L  15
 None
 1.31A 4o2bD-5fmgL:
undetectable		 4o2bD-5fmgL:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5fmg PROTEASOME SUBUNIT
ALPHA, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 GLY A 144
SER A 143
ILE A  75
ASN A  74
GLY A  83
 None
 1.11A 4obwA-5fmgA:
undetectable		 4obwA-5fmgA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 VAL I  63
GLY I 102
ILE I  37
LEU I 100
VAL I  76
 None
 1.02A 4qdjA-5fmgI:
undetectable		 4qdjA-5fmgI:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.12A 4qvlK-5fmgI:
27.9
4qvlL-5fmgI:
23.8		 4qvlK-5fmgI:
26.29
4qvlL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.97A 4qvlK-5fmgI:
27.9
4qvlL-5fmgI:
23.8		 4qvlK-5fmgI:
26.29
4qvlL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.81A 4qvlK-5fmgI:
27.9
4qvlL-5fmgI:
23.8		 4qvlK-5fmgI:
26.29
4qvlL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.58A 4qvlK-5fmgL:
28.4
4qvlL-5fmgL:
23.8		 4qvlK-5fmgL:
47.89
4qvlL-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.12A 4qvlY-5fmgI:
16.6
4qvlZ-5fmgI:
23.5		 4qvlY-5fmgI:
26.29
4qvlZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 4qvlY-5fmgI:
16.6
4qvlZ-5fmgI:
23.5		 4qvlY-5fmgI:
26.29
4qvlZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 4qvlY-5fmgI:
16.6
4qvlZ-5fmgI:
23.5		 4qvlY-5fmgI:
26.29
4qvlZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.57A 4qvlY-5fmgL:
16.6
4qvlZ-5fmgL:
23.7		 4qvlY-5fmgL:
47.89
4qvlZ-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.14A 4qvmK-5fmgI:
27.9
4qvmL-5fmgI:
23.7		 4qvmK-5fmgI:
26.29
4qvmL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.95A 4qvmK-5fmgI:
27.9
4qvmL-5fmgI:
23.7		 4qvmK-5fmgI:
26.29
4qvmL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.81A 4qvmK-5fmgI:
27.9
4qvmL-5fmgI:
23.7		 4qvmK-5fmgI:
26.29
4qvmL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.59A 4qvmK-5fmgL:
28.4
4qvmL-5fmgL:
23.9		 4qvmK-5fmgL:
47.42
4qvmL-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.14A 4qvmY-5fmgI:
21.4
4qvmZ-5fmgI:
23.4		 4qvmY-5fmgI:
26.29
4qvmZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.95A 4qvmY-5fmgI:
21.4
4qvmZ-5fmgI:
23.4		 4qvmY-5fmgI:
26.29
4qvmZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.81A 4qvmY-5fmgI:
21.4
4qvmZ-5fmgI:
23.4		 4qvmY-5fmgI:
26.29
4qvmZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.59A 4qvmY-5fmgL:
16.7
4qvmZ-5fmgL:
7.3		 4qvmY-5fmgL:
47.42
4qvmZ-5fmgL:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.92A 4qvnV-5fmgI:
30.1
4qvnb-5fmgI:
28.3		 4qvnV-5fmgI:
48.94
4qvnb-5fmgI:
27.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.50A 4qvnV-5fmgI:
30.1
4qvnb-5fmgI:
28.3		 4qvnV-5fmgI:
48.94
4qvnb-5fmgI:
27.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.10A 4qvnK-5fmgI:
28.0
4qvnL-5fmgI:
23.8		 4qvnK-5fmgI:
26.29
4qvnL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 4qvnK-5fmgI:
28.0
4qvnL-5fmgI:
23.8		 4qvnK-5fmgI:
26.29
4qvnL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.92A 4qvnH-5fmgI:
28.6
4qvnN-5fmgI:
28.3		 4qvnH-5fmgI:
48.94
4qvnN-5fmgI:
27.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.49A 4qvnH-5fmgI:
28.6
4qvnN-5fmgI:
28.3		 4qvnH-5fmgI:
48.94
4qvnN-5fmgI:
27.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.10A 4qvnY-5fmgI:
16.7
4qvnZ-5fmgI:
23.5		 4qvnY-5fmgI:
26.29
4qvnZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.79A 4qvnY-5fmgI:
16.7
4qvnZ-5fmgI:
23.5		 4qvnY-5fmgI:
26.29
4qvnZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.07A 4qvpH-5fmgI:
28.6
4qvpI-5fmgI:
26.6		 4qvpH-5fmgI:
48.94
4qvpI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.84A 4qvpH-5fmgI:
28.6
4qvpI-5fmgI:
26.6		 4qvpH-5fmgI:
48.94
4qvpI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.74A 4qvpH-5fmgI:
28.6
4qvpI-5fmgI:
26.6		 4qvpH-5fmgI:
48.94
4qvpI-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.08A 4qvpK-5fmgI:
27.8
4qvpL-5fmgI:
23.5		 4qvpK-5fmgI:
26.29
4qvpL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 0.93A 4qvpK-5fmgI:
27.8
4qvpL-5fmgI:
23.5		 4qvpK-5fmgI:
26.29
4qvpL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 4qvpK-5fmgI:
27.8
4qvpL-5fmgI:
23.5		 4qvpK-5fmgI:
26.29
4qvpL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 4qvpK-5fmgI:
27.8
4qvpL-5fmgI:
23.5		 4qvpK-5fmgI:
26.29
4qvpL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.55A 4qvpK-5fmgI:
27.8
4qvpL-5fmgI:
23.5		 4qvpK-5fmgI:
26.29
4qvpL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.54A 4qvpK-5fmgL:
28.3
4qvpL-5fmgL:
23.5		 4qvpK-5fmgL:
47.42
4qvpL-5fmgL:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.06A 4qvpV-5fmgI:
30.2
4qvpW-5fmgI:
26.6		 4qvpV-5fmgI:
48.94
4qvpW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.83A 4qvpV-5fmgI:
30.2
4qvpW-5fmgI:
26.6		 4qvpV-5fmgI:
48.94
4qvpW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.74A 4qvpV-5fmgI:
30.2
4qvpW-5fmgI:
26.6		 4qvpV-5fmgI:
48.94
4qvpW-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.08A 4qvpY-5fmgI:
16.6
4qvpZ-5fmgI:
23.5		 4qvpY-5fmgI:
26.29
4qvpZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 0.93A 4qvpY-5fmgI:
16.6
4qvpZ-5fmgI:
23.5		 4qvpY-5fmgI:
26.29
4qvpZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 4qvpY-5fmgI:
16.6
4qvpZ-5fmgI:
23.5		 4qvpY-5fmgI:
26.29
4qvpZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 4qvpY-5fmgI:
16.6
4qvpZ-5fmgI:
23.5		 4qvpY-5fmgI:
26.29
4qvpZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.55A 4qvpY-5fmgI:
16.6
4qvpZ-5fmgI:
23.5		 4qvpY-5fmgI:
26.29
4qvpZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.54A 4qvpY-5fmgL:
16.7
4qvpZ-5fmgL:
23.7		 4qvpY-5fmgL:
47.42
4qvpZ-5fmgL:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I   1
LYS I  33
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.16A 4qvqH-5fmgI:
28.6
4qvqI-5fmgI:
26.5		 4qvqH-5fmgI:
48.94
4qvqI-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.08A 4qvqK-5fmgI:
28.0
4qvqL-5fmgI:
23.8		 4qvqK-5fmgI:
26.29
4qvqL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 4qvqK-5fmgI:
28.0
4qvqL-5fmgI:
23.8		 4qvqK-5fmgI:
26.29
4qvqL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.09A 4qvqY-5fmgI:
16.7
4qvqZ-5fmgI:
23.4		 4qvqY-5fmgI:
26.29
4qvqZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.79A 4qvqY-5fmgI:
16.7
4qvqZ-5fmgI:
23.4		 4qvqY-5fmgI:
26.29
4qvqZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.83A 4qvvH-5fmgI:
28.6		 4qvvH-5fmgI:
48.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.75A 4qvvH-5fmgI:
28.6		 4qvvH-5fmgI:
48.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.83A 4qvvV-5fmgI:
30.2		 4qvvV-5fmgI:
48.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.75A 4qvvV-5fmgI:
30.2		 4qvvV-5fmgI:
48.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR I   1
LYS I  33
ALA I  46
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.20A 4qvwH-5fmgI:
28.7
4qvwI-5fmgI:
26.6		 4qvwH-5fmgI:
48.94
4qvwI-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.13A 4qvwK-5fmgI:
27.9
4qvwL-5fmgI:
23.7		 4qvwK-5fmgI:
25.86
4qvwL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.97A 4qvwK-5fmgI:
27.9
4qvwL-5fmgI:
23.7		 4qvwK-5fmgI:
25.86
4qvwL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR I   1
LYS I  33
ALA I  46
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.20A 4qvwV-5fmgI:
30.2
4qvwW-5fmgI:
26.5		 4qvwV-5fmgI:
48.94
4qvwW-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.13A 4qvwY-5fmgI:
16.6
4qvwZ-5fmgI:
23.4		 4qvwY-5fmgI:
25.86
4qvwZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.97A 4qvwY-5fmgI:
16.6
4qvwZ-5fmgI:
23.4		 4qvwY-5fmgI:
25.86
4qvwZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.85A 4qvyH-5fmgI:
28.7		 4qvyH-5fmgI:
48.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.78A 4qvyH-5fmgI:
28.7		 4qvyH-5fmgI:
48.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-2.6A)
 1.17A 4qvyK-5fmgI:
27.9
4qvyL-5fmgI:
23.7		 4qvyK-5fmgI:
25.86
4qvyL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.98A 4qvyK-5fmgI:
27.9
4qvyL-5fmgI:
23.7		 4qvyK-5fmgI:
25.86
4qvyL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.09A 4qvyV-5fmgI:
30.3
4qvyW-5fmgI:
26.6		 4qvyV-5fmgI:
48.94
4qvyW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.79A 4qvyV-5fmgI:
30.3
4qvyW-5fmgI:
26.6		 4qvyV-5fmgI:
48.94
4qvyW-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-2.6A)
 1.16A 4qvyY-5fmgI:
21.6
4qvyZ-5fmgI:
23.4		 4qvyY-5fmgI:
25.86
4qvyZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.98A 4qvyY-5fmgI:
21.6
4qvyZ-5fmgI:
23.4		 4qvyY-5fmgI:
25.86
4qvyZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.09A 4qw0H-5fmgI:
28.6
4qw0I-5fmgI:
26.4		 4qw0H-5fmgI:
48.94
4qw0I-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 THR I   1
ALA I  20
THR I  21
LYS I  33
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
 0.90A 4qw0K-5fmgI:
27.7		 4qw0K-5fmgI:
25.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.10A 4qw0V-5fmgI:
30.2
4qw0W-5fmgI:
26.5		 4qw0V-5fmgI:
48.94
4qw0W-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 THR I   1
ALA I  20
THR I  21
LYS I  33
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
 0.90A 4qw0Y-5fmgI:
21.4		 4qw0Y-5fmgI:
25.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.09A 4qw1H-5fmgI:
28.6
4qw1I-5fmgI:
26.6		 4qw1H-5fmgI:
48.94
4qw1I-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.90A 4qw1H-5fmgI:
28.6
4qw1I-5fmgI:
26.6		 4qw1H-5fmgI:
48.94
4qw1I-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 4qw1H-5fmgI:
28.6
4qw1I-5fmgI:
26.6		 4qw1H-5fmgI:
48.94
4qw1I-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.11A 4qw1K-5fmgI:
28.0
4qw1L-5fmgI:
23.8		 4qw1K-5fmgI:
26.29
4qw1L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 4qw1K-5fmgI:
28.0
4qw1L-5fmgI:
23.8		 4qw1K-5fmgI:
26.29
4qw1L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 4qw1K-5fmgI:
28.0
4qw1L-5fmgI:
23.8		 4qw1K-5fmgI:
26.29
4qw1L-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.55A 4qw1K-5fmgL:
28.4
4qw1L-5fmgL:
23.9		 4qw1K-5fmgL:
47.42
4qw1L-5fmgL:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.08A 4qw1V-5fmgI:
30.2
4qw1W-5fmgI:
26.6		 4qw1V-5fmgI:
48.94
4qw1W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.89A 4qw1V-5fmgI:
30.2
4qw1W-5fmgI:
26.6		 4qw1V-5fmgI:
48.94
4qw1W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.75A 4qw1V-5fmgI:
30.2
4qw1W-5fmgI:
26.6		 4qw1V-5fmgI:
48.94
4qw1W-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.12A 4qw1Y-5fmgI:
16.7
4qw1Z-5fmgI:
23.5		 4qw1Y-5fmgI:
26.29
4qw1Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 4qw1Y-5fmgI:
16.7
4qw1Z-5fmgI:
23.5		 4qw1Y-5fmgI:
26.29
4qw1Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 4qw1Y-5fmgI:
16.7
4qw1Z-5fmgI:
23.5		 4qw1Y-5fmgI:
26.29
4qw1Z-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.56A 4qw1Y-5fmgL:
16.6
4qw1Z-5fmgL:
23.7		 4qw1Y-5fmgL:
47.42
4qw1Z-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.14A 4qw3K-5fmgI:
27.7
4qw3L-5fmgI:
23.6		 4qw3K-5fmgI:
26.29
4qw3L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 4qw3K-5fmgI:
27.7
4qw3L-5fmgI:
23.6		 4qw3K-5fmgI:
26.29
4qw3L-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.81A 4qw3K-5fmgI:
27.7
4qw3L-5fmgI:
23.6		 4qw3K-5fmgI:
26.29
4qw3L-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.60A 4qw3K-5fmgL:
28.4
4qw3L-5fmgL:
23.8		 4qw3K-5fmgL:
47.89
4qw3L-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.14A 4qw3Y-5fmgI:
16.4
4qw3Z-5fmgI:
23.3		 4qw3Y-5fmgI:
26.29
4qw3Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 4qw3Y-5fmgI:
16.4
4qw3Z-5fmgI:
23.3		 4qw3Y-5fmgI:
26.29
4qw3Z-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 4qw3Y-5fmgI:
16.4
4qw3Z-5fmgI:
23.3		 4qw3Y-5fmgI:
26.29
4qw3Z-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.60A 4qw3Y-5fmgL:
16.7
4qw3Z-5fmgL:
23.7		 4qw3Y-5fmgL:
47.89
4qw3Z-5fmgL:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.29A 4qwuK-5fmgI:
27.2
4qwuL-5fmgI:
23.6		 4qwuK-5fmgI:
26.29
4qwuL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.10A 4qwuK-5fmgI:
27.2
4qwuL-5fmgI:
23.6		 4qwuK-5fmgI:
26.29
4qwuL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.38A 4qwuY-5fmgI:
16.7
4qwuZ-5fmgI:
23.5		 4qwuY-5fmgI:
26.29
4qwuZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.19A 4qwuY-5fmgI:
16.7
4qwuZ-5fmgI:
23.5		 4qwuY-5fmgI:
26.29
4qwuZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 ALA I  46
GLY I  15
ALA I  16
SER I 169
 None
 0.89A 4r1zB-5fmgI:
undetectable		 4r1zB-5fmgI:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 ALA I 126
GLY I  45
ALA I  46
SER I 169
 None
 0.86A 4r1zB-5fmgI:
undetectable		 4r1zB-5fmgI:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA H 166
ALA N  35
LEU N  58
GLY H 171
GLN N  62
 None
 0.85A 4r38A-5fmgH:
undetectable		 4r38A-5fmgH:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA H 166
ALA N  35
LEU N  58
GLY H 171
GLN N  62
 None
 0.91A 4r38B-5fmgH:
undetectable		 4r38B-5fmgH:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA H 166
ALA N  35
LEU N  58
GLY H 171
GLN N  62
 None
 0.84A 4r38C-5fmgH:
undetectable		 4r38C-5fmgH:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA H 166
ALA N  35
LEU N  58
GLY H 171
GLN N  62
 None
 0.85A 4r38D-5fmgH:
undetectable		 4r38D-5fmgH:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 ALA H 166
ALA N  35
LEU N  58
GLY H 171
GLN N  62
 None
 0.83A 4r3aB-5fmgH:
undetectable		 4r3aB-5fmgH:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 7 THR M  55
GLY M  38
ALA M  53
ILE M  71
 None
 0.96A 4txnD-5fmgM:
undetectable		 4txnD-5fmgM:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 6 GLY L 190
GLU L 189
ASP L  17
ASP L 192
 None
 0.81A 4uckB-5fmgL:
undetectable		 4uckB-5fmgL:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		3 / 3 SER E  35
ALA E  37
VAL E  38
 None
 0.58A 4x1iA-5fmgE:
undetectable		 4x1iA-5fmgE:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 12 LEU C 212
LEU C  37
THR C 170
ALA C 163
ILE C  33
 None
 1.12A 4x1yB-5fmgC:
undetectable		 4x1yB-5fmgC:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		4 / 6 LEU B  87
ASP B  82
ILE B  72
PRO B 151
 None
 0.86A 4xi3C-5fmgB:
undetectable		 4xi3C-5fmgB:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 SER M  82
HIS M  93
ILE M  89
LEU M 120
LEU M 138
 None
 1.02A 4xumA-5fmgM:
undetectable		 4xumA-5fmgM:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		5 / 12 SER F  54
ALA E 200
GLU E 180
LEU E 144
THR E 165
 None
 1.30A 4zjoA-5fmgF:
undetectable		 4zjoA-5fmgF:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		4 / 8 GLY C 137
ALA C  77
GLY C  75
PHE C  73
 None
 0.74A 5albL-5fmgC:
undetectable		 5albL-5fmgC:
19.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.09A 5bxnH-5fmgI:
30.1
5bxnI-5fmgI:
26.7		 5bxnH-5fmgI:
48.51
5bxnI-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.09A 5bxnK-5fmgI:
27.9
5bxnL-5fmgI:
23.5		 5bxnK-5fmgI:
26.29
5bxnL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.93A 5bxnK-5fmgI:
27.9
5bxnL-5fmgI:
23.5		 5bxnK-5fmgI:
26.29
5bxnL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.79A 5bxnK-5fmgI:
27.9
5bxnL-5fmgI:
23.5		 5bxnK-5fmgI:
26.29
5bxnL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.56A 5bxnK-5fmgL:
28.4
5bxnL-5fmgL:
23.5		 5bxnK-5fmgL:
47.89
5bxnL-5fmgL:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.04A 5bxnV-5fmgI:
30.2
5bxnW-5fmgI:
26.7		 5bxnV-5fmgI:
48.51
5bxnW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
THR I  21
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.90A 5bxnV-5fmgI:
30.2
5bxnW-5fmgI:
26.7		 5bxnV-5fmgI:
48.51
5bxnW-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.12A 5bxnY-5fmgI:
16.7
5bxnZ-5fmgI:
23.4		 5bxnY-5fmgI:
26.29
5bxnZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.93A 5bxnY-5fmgI:
16.7
5bxnZ-5fmgI:
23.4		 5bxnY-5fmgI:
26.29
5bxnZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.79A 5bxnY-5fmgI:
16.7
5bxnZ-5fmgI:
23.4		 5bxnY-5fmgI:
26.29
5bxnZ-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.57A 5bxnY-5fmgL:
16.7
5bxnZ-5fmgL:
23.6		 5bxnY-5fmgL:
47.89
5bxnZ-5fmgL:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.08A 5cz7V-5fmgI:
30.2
5cz7W-5fmgI:
26.6		 5cz7V-5fmgI:
48.94
5cz7W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.87A 5cz7V-5fmgI:
30.2
5cz7W-5fmgI:
26.6		 5cz7V-5fmgI:
48.94
5cz7W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.75A 5cz7V-5fmgI:
30.2
5cz7W-5fmgI:
26.6		 5cz7V-5fmgI:
48.94
5cz7W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
LYS I  33
ALA I  46
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.17A 5d0xH-5fmgI:
28.7
5d0xI-5fmgI:
26.4		 5d0xH-5fmgI:
48.94
5d0xI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
ALA I  46
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
None
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.92A 5d0xH-5fmgI:
28.7
5d0xI-5fmgI:
26.4		 5d0xH-5fmgI:
48.94
5d0xI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
CYH I  31
ALA I  46
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.5A)
 0.81A 5d0xH-5fmgI:
28.7
5d0xI-5fmgI:
26.4		 5d0xH-5fmgI:
48.94
5d0xI-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.10A 5d0xK-5fmgI:
27.9
5d0xL-5fmgI:
23.7		 5d0xK-5fmgI:
25.86
5d0xL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 5d0xK-5fmgI:
27.9
5d0xL-5fmgI:
23.7		 5d0xK-5fmgI:
25.86
5d0xL-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 5d0xK-5fmgI:
27.9
5d0xL-5fmgI:
23.7		 5d0xK-5fmgI:
25.86
5d0xL-5fmgI:
21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 5d0xV-5fmgI:
30.2		 5d0xV-5fmgI:
48.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.10A 5d0xY-5fmgI:
21.4
5d0xZ-5fmgI:
23.4		 5d0xY-5fmgI:
25.86
5d0xZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
 0.96A 5d0xY-5fmgI:
21.4
5d0xZ-5fmgI:
23.4		 5d0xY-5fmgI:
25.86
5d0xZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 9 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 5d0xY-5fmgI:
21.4
5d0xZ-5fmgI:
23.4		 5d0xY-5fmgI:
25.86
5d0xZ-5fmgI:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		3 / 3 SER E  35
ALA E  37
VAL E  38
 None
 0.57A 5eypA-5fmgE:
undetectable		 5eypA-5fmgE:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 4 THR I  55
LEU I  52
HIS I  35
GLY I  50
 None
7F1  I 300 (-3.4A)
None
None
 1.37A 5gwyA-5fmgI:
undetectable		 5gwyA-5fmgI:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 12 LEU C 212
LEU C  37
THR C 170
ALA C 163
ILE C  33
 None
 1.08A 5itzB-5fmgC:
undetectable		 5itzB-5fmgC:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR N 178
ALA N 116
LEU N 159
PHE N 163
GLY N 162
 None
 1.49A 5jglA-5fmgN:
undetectable		 5jglA-5fmgN:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 12 ILE C  33
ILE C  35
LEU C 196
LEU C 135
HIS C 149
 None
 1.17A 5km9B-5fmgC:
undetectable		 5km9B-5fmgC:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		4 / 5 PHE C  12
SER C  13
ASN C 155
ASP C 151
 None
 1.33A 5kpcA-5fmgC:
undetectable		 5kpcA-5fmgC:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.08A 5l5fH-5fmgI:
28.6
5l5fI-5fmgI:
26.6		 5l5fH-5fmgI:
48.94
5l5fI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.62A 5l5fH-5fmgI:
28.6
5l5fI-5fmgI:
26.6		 5l5fH-5fmgI:
48.94
5l5fI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 THR L   1
SER L  21
VAL L  31
MET L  45
ALA L  49
 None
 0.85A 5l5fK-5fmgL:
28.4
5l5fL-5fmgL:
23.5		 5l5fK-5fmgL:
48.58
5l5fL-5fmgL:
23.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.07A 5l5fV-5fmgI:
30.2
5l5fW-5fmgI:
26.6		 5l5fV-5fmgI:
48.94
5l5fW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.61A 5l5fV-5fmgI:
30.2
5l5fW-5fmgI:
26.6		 5l5fV-5fmgI:
48.94
5l5fW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 8 THR L   1
SER L  21
MET L  45
ALA L  49
 None
 0.76A 5l5fY-5fmgL:
28.4
5l5fZ-5fmgL:
23.7		 5l5fY-5fmgL:
48.58
5l5fZ-5fmgL:
23.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 12 HIS I 114
SER I 118
THR H  20
SER H  46
GLY H  47
 None
 0.89A 5l5zV-5fmgI:
30.2
5l5zb-5fmgI:
28.3		 5l5zV-5fmgI:
48.94
5l5zb-5fmgI:
27.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.10A 5l5zH-5fmgI:
28.5
5l5zI-5fmgI:
26.7		 5l5zH-5fmgI:
48.94
5l5zI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
THR I  21
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.92A 5l5zH-5fmgI:
28.5
5l5zI-5fmgI:
26.7		 5l5zH-5fmgI:
48.94
5l5zI-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.80A 5l5zH-5fmgI:
28.5
5l5zI-5fmgI:
26.7		 5l5zH-5fmgI:
48.94
5l5zI-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.18A 5l5zK-5fmgI:
10.5
5l5zL-5fmgI:
23.5		 5l5zK-5fmgI:
27.04
5l5zL-5fmgI:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.81A 5l5zK-5fmgI:
10.5
5l5zL-5fmgI:
23.5		 5l5zK-5fmgI:
27.04
5l5zL-5fmgI:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.09A 5l5zV-5fmgI:
30.2
5l5zW-5fmgI:
26.7		 5l5zV-5fmgI:
48.94
5l5zW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
THR I  21
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.92A 5l5zV-5fmgI:
30.2
5l5zW-5fmgI:
26.7		 5l5zV-5fmgI:
48.94
5l5zW-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L5Z_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.79A 5l5zV-5fmgI:
30.2
5l5zW-5fmgI:
26.7		 5l5zV-5fmgI:
48.94
5l5zW-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.19A 5l5zY-5fmgI:
28.2
5l5zZ-5fmgI:
23.4		 5l5zY-5fmgI:
27.04
5l5zZ-5fmgI:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 9 THR I   1
ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.82A 5l5zY-5fmgI:
28.2
5l5zZ-5fmgI:
23.4		 5l5zY-5fmgI:
27.04
5l5zZ-5fmgI:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.08A 5l66H-5fmgI:
28.6
5l66I-5fmgI:
26.7		 5l66H-5fmgI:
48.94
5l66I-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.87A 5l66H-5fmgI:
28.6
5l66I-5fmgI:
26.7		 5l66H-5fmgI:
48.94
5l66I-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.74A 5l66H-5fmgI:
28.6
5l66I-5fmgI:
26.7		 5l66H-5fmgI:
48.94
5l66I-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.16A 5l66K-5fmgI:
14.0
5l66L-5fmgI:
23.7		 5l66K-5fmgI:
25.22
5l66L-5fmgI:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.75A 5l66K-5fmgI:
14.0
5l66L-5fmgI:
23.7		 5l66K-5fmgI:
25.22
5l66L-5fmgI:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.08A 5l66V-5fmgI:
30.1
5l66W-5fmgI:
26.6		 5l66V-5fmgI:
48.94
5l66W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.87A 5l66V-5fmgI:
30.1
5l66W-5fmgI:
26.6		 5l66V-5fmgI:
48.94
5l66W-5fmgI:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L66_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.74A 5l66V-5fmgI:
30.1
5l66W-5fmgI:
26.6		 5l66V-5fmgI:
48.94
5l66W-5fmgI:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.16A 5l66Y-5fmgI:
21.2
5l66Z-5fmgI:
23.4		 5l66Y-5fmgI:
25.22
5l66Z-5fmgI:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 10 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.75A 5l66Y-5fmgI:
21.2
5l66Z-5fmgI:
23.4		 5l66Y-5fmgI:
25.22
5l66Z-5fmgI:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.89A 5lf3b-5fmgI:
28.5		 5lf3b-5fmgI:
28.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.78A 5lf3H-5fmgI:
31.3
5lf3I-5fmgI:
27.0		 5lf3H-5fmgI:
54.27
5lf3I-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
GLU I  22
ALA I  46
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 0.95A 5lf3H-5fmgI:
31.3
5lf3I-5fmgI:
27.0		 5lf3H-5fmgI:
54.27
5lf3I-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.67A 5lf3H-5fmgI:
31.3
5lf3I-5fmgI:
27.0		 5lf3H-5fmgI:
54.27
5lf3I-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 10 THR I   1
ALA I  20
THR I  21
GLU I  22
CYH I  31
ALA I  46
GLY I  47
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
 0.96A 5lf3H-5fmgI:
31.3
5lf3I-5fmgI:
27.0		 5lf3H-5fmgI:
54.27
5lf3I-5fmgI:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
ALA L  46
GLY L  47
ALA L  49
 None
 0.60A 5lf3H-5fmgL:
28.7
5lf3I-5fmgL:
26.2		 5lf3H-5fmgL:
25.86
5lf3I-5fmgL:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.99A 5lf3K-5fmgI:
29.0
5lf3L-5fmgI:
24.9		 5lf3K-5fmgI:
25.32
5lf3L-5fmgI:
24.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.61A 5lf3K-5fmgL:
29.3
5lf3L-5fmgL:
25.0		 5lf3K-5fmgL:
52.91
5lf3L-5fmgL:
27.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_K_BO2K305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
MET L  45
GLY L  47
GLY L  48
ALA L  49
 None
 0.67A 5lf3K-5fmgL:
29.3
5lf3L-5fmgL:
25.0		 5lf3K-5fmgL:
52.91
5lf3L-5fmgL:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.88A 5lf3N-5fmgI:
28.5		 5lf3N-5fmgI:
28.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		8 / 10 THR I   1
ALA I  20
THR I  21
GLU I  22
LYS I  33
ALA I  46
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.09A 5lf3V-5fmgI:
31.2
5lf3W-5fmgI:
27.1		 5lf3V-5fmgI:
54.27
5lf3W-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		8 / 10 THR I   1
ALA I  20
THR I  21
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.91A 5lf3V-5fmgI:
31.2
5lf3W-5fmgI:
27.1		 5lf3V-5fmgI:
54.27
5lf3W-5fmgI:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 10 THR L   1
ALA L  20
ALA L  46
GLY L  47
ALA L  49
 None
 0.60A 5lf3V-5fmgL:
28.6
5lf3W-5fmgL:
26.2		 5lf3V-5fmgL:
25.86
5lf3W-5fmgL:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg BETA3 PROTEASOME
SUBUNIT, PUTATIVE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		7 / 11 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.99A 5lf3Y-5fmgI:
29.0
5lf3Z-5fmgI:
24.9		 5lf3Y-5fmgI:
25.32
5lf3Z-5fmgI:
24.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.61A 5lf3Y-5fmgL:
29.3
5lf3Z-5fmgL:
25.0		 5lf3Y-5fmgL:
52.91
5lf3Z-5fmgL:
27.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_Y_BO2Y305_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-1)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
MET L  45
GLY L  47
GLY L  48
ALA L  49
 None
 0.68A 5lf3Y-5fmgL:
29.3
5lf3Z-5fmgL:
25.0		 5lf3Y-5fmgL:
52.91
5lf3Z-5fmgL:
27.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.98A 5lf7V-5fmgI:
31.2
5lf7b-5fmgI:
28.6		 5lf7V-5fmgI:
54.27
5lf7b-5fmgI:
28.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.65A 5lf7V-5fmgI:
31.2
5lf7b-5fmgI:
28.6		 5lf7V-5fmgI:
54.27
5lf7b-5fmgI:
28.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
ALA L  46
GLY L  47
ALA L  49
 None
 0.59A 5lf7H-5fmgL:
28.7
5lf7I-5fmgL:
26.3		 5lf7H-5fmgL:
25.86
5lf7I-5fmgL:
24.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
ALA I  46
GLY I  47
ALA I  49
ASP J 138
LEU J 139
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
None
 0.80A 5lf7H-5fmgI:
31.3
5lf7I-5fmgI:
27.1		 5lf7H-5fmgI:
54.27
5lf7I-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
LEU J 139
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
None
 0.62A 5lf7H-5fmgI:
31.3
5lf7I-5fmgI:
27.1		 5lf7H-5fmgI:
54.27
5lf7I-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
GLU I  22
ALA I  46
GLY I  47
ASP J 138
LEU J 139
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
None
 1.05A 5lf7H-5fmgI:
31.3
5lf7I-5fmgI:
27.1		 5lf7H-5fmgI:
54.27
5lf7I-5fmgI:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.74A 5lf7K-5fmgI:
29.1
5lf7L-5fmgI:
25.0		 5lf7K-5fmgI:
25.32
5lf7L-5fmgI:
24.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR L   1
ALA L  20
VAL L  31
GLY L  47
GLY L  48
ALA L  49
 None
 0.73A 5lf7K-5fmgL:
29.5
5lf7L-5fmgL:
25.1		 5lf7K-5fmgL:
52.91
5lf7L-5fmgL:
27.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR L   1
VAL L  31
MET L  45
GLY L  47
GLY L  48
ALA L  49
 None
 0.76A 5lf7K-5fmgL:
29.5
5lf7L-5fmgL:
25.1		 5lf7K-5fmgL:
52.91
5lf7L-5fmgL:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_K_6V8K305_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.09A 5lf7K-5fmgI:
29.1
5lf7L-5fmgI:
25.0		 5lf7K-5fmgI:
25.32
5lf7L-5fmgI:
24.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.96A 5lf7H-5fmgI:
31.3
5lf7N-5fmgI:
28.6		 5lf7H-5fmgI:
54.27
5lf7N-5fmgI:
28.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.64A 5lf7H-5fmgI:
31.3
5lf7N-5fmgI:
28.6		 5lf7H-5fmgI:
54.27
5lf7N-5fmgI:
28.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
ALA L  46
GLY L  47
ALA L  49
 None
 0.60A 5lf7V-5fmgL:
28.7
5lf7W-5fmgL:
26.2		 5lf7V-5fmgL:
25.86
5lf7W-5fmgL:
24.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
ALA I  46
GLY I  47
ALA I  49
ASP J 138
LEU J 139
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
None
 0.81A 5lf7V-5fmgI:
31.2
5lf7W-5fmgI:
27.1		 5lf7V-5fmgI:
54.27
5lf7W-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
CYH I  31
ALA I  46
GLY I  47
ALA I  49
LEU J 139
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
None
 0.63A 5lf7V-5fmgI:
31.2
5lf7W-5fmgI:
27.1		 5lf7V-5fmgI:
54.27
5lf7W-5fmgI:
20.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		8 / 11 THR I   1
ALA I  20
THR I  21
GLU I  22
ALA I  46
GLY I  47
ASP J 138
LEU J 139
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
None
None
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
None
 1.06A 5lf7V-5fmgI:
31.2
5lf7W-5fmgI:
27.1		 5lf7V-5fmgI:
54.27
5lf7W-5fmgI:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.74A 5lf7Y-5fmgI:
29.1
5lf7Z-5fmgI:
24.9		 5lf7Y-5fmgI:
25.32
5lf7Z-5fmgI:
24.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR L   1
ALA L  20
VAL L  31
GLY L  47
GLY L  48
ALA L  49
 None
 0.71A 5lf7Y-5fmgL:
29.5
5lf7Z-5fmgL:
25.0		 5lf7Y-5fmgL:
52.91
5lf7Z-5fmgL:
27.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR L   1
VAL L  31
MET L  45
GLY L  47
GLY L  48
ALA L  49
 None
 0.76A 5lf7Y-5fmgL:
29.5
5lf7Z-5fmgL:
25.0		 5lf7Y-5fmgL:
52.91
5lf7Z-5fmgL:
27.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_Y_6V8Y306_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.08A 5lf7Y-5fmgI:
29.1
5lf7Z-5fmgI:
24.9		 5lf7Y-5fmgI:
25.32
5lf7Z-5fmgI:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 12 ALA C 192
ILE C  33
GLY C  75
LEU C 147
ILE C  44
 None
 1.09A 5m24A-5fmgC:
undetectable		 5m24A-5fmgC:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 5fmg PROTEASOME COMPONENT
C8, PUTATIVE
(Plasmodium
falciparum) 		5 / 10 ILE G 151
THR G  79
ILE G  78
ILE G  77
ILE G  76
 None
 1.02A 5murE-5fmgG:
undetectable		 5murE-5fmgG:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		5 / 12 ALA C  47
ILE C 164
GLY C 165
SER C  32
LEU C  45
 None
 1.19A 5nfjC-5fmgC:
undetectable		 5nfjC-5fmgC:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 GLY I 102
GLY I  15
GLY I   5
GLY I 101
VAL I 173
ILE I 175
 None
 1.38A 5njvC-5fmgI:
undetectable		 5njvC-5fmgI:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum) 		4 / 8 LEU D 132
ALA D 134
ILE D 107
ALA D 108
 None
 0.83A 5te8B-5fmgD:
undetectable		 5te8B-5fmgD:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE 2,
PUTATIVE
(Plasmodium
falciparum) 		5 / 12 GLN B 148
SER B 133
ILE B 114
ASP B  82
PHE B  83
 None
 1.43A 5vlmA-5fmgB:
undetectable		 5vlmA-5fmgB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWO_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 ALA L 163
ILE L 160
GLY L 190
SER L  18
GLY L 171
 None
 1.28A 6awoA-5fmgL:
undetectable		 6awoA-5fmgL:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWQ_A_SREA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 9 ALA L 163
ILE L 160
GLY L 190
SER L  18
GLY L 171
 None
 1.29A 6awqA-5fmgL:
undetectable		 6awqA-5fmgL:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum;
Plasmodium
falciparum;
Plasmodium
falciparum) 		5 / 12 GLY L  43
ARG M 128
ILE E 102
LYS L  57
GLY L  60
 None
 1.16A 6c2mB-5fmgL:
undetectable		 6c2mB-5fmgL:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CHG_C_SAMC1101_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-4 SPECIFIC)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 ILE L 179
HIS L 180
ASN L 182
HIS L 178
LEU L 149
 None
 1.07A 6chgC-5fmgL:
undetectable		 6chgC-5fmgL:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 5fmg PROTEASOME, PUTATIVE
(Plasmodium
falciparum) 		5 / 10 ASP H 157
VAL H  12
ILE H  37
VAL H 231
ILE H 233
 None
 0.82A 6dj2A-5fmgH:
undetectable		 6dj2A-5fmgH:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		5 / 9 ASP K   2
GLY L 118
SER L  84
ASN K  33
VAL L 121
 None
 1.29A 6giqA-5fmgK:
undetectable
6giqE-5fmgK:
undetectable
6giqI-5fmgK:
undetectable		 6giqA-5fmgK:
17.10
6giqE-5fmgK:
21.79
6giqI-5fmgK:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		5 / 10 ASP K   2
GLY L 118
SER L  84
ASN K  33
VAL L 121
 None
 1.47A 6hu9L-5fmgK:
undetectable
6hu9P-5fmgK:
undetectable
6hu9T-5fmgK:
undetectable		 6hu9L-5fmgK:
17.32
6hu9P-5fmgK:
20.83
6hu9T-5fmgK:
13.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.90A 6hwdV-5fmgI:
30.2
6hwdb-5fmgI:
28.4		 6hwdV-5fmgI:
37.80
6hwdb-5fmgI:
17.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.52A 6hwdV-5fmgI:
30.2
6hwdb-5fmgI:
28.4		 6hwdV-5fmgI:
37.80
6hwdb-5fmgI:
17.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 12 THR I   1
ALA I  27
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.71A 6hwdH-5fmgI:
28.7
6hwdI-5fmgI:
26.6		 6hwdH-5fmgI:
37.80
6hwdI-5fmgI:
15.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 12 ALA I  27
LYS I  33
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 1.06A 6hwdH-5fmgI:
28.7
6hwdI-5fmgI:
26.6		 6hwdH-5fmgI:
37.80
6hwdI-5fmgI:
15.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 12 THR I   1
ALA I  27
ALA I  46
GLY I  47
ALA I  49
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
7F1  I 300 (-2.6A)
 0.87A 6hwdH-5fmgI:
28.7
6hwdI-5fmgI:
26.6		 6hwdH-5fmgI:
37.80
6hwdI-5fmgI:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 6hwdK-5fmgI:
28.0
6hwdL-5fmgI:
23.9		 6hwdK-5fmgI:
18.78
6hwdL-5fmgI:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.58A 6hwdK-5fmgI:
28.0
6hwdL-5fmgI:
23.9		 6hwdK-5fmgI:
18.78
6hwdL-5fmgI:
17.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.53A 6hwdK-5fmgL:
28.5
6hwdL-5fmgL:
23.8		 6hwdK-5fmgL:
63.75
6hwdL-5fmgL:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
MET L  45
GLY L  47
GLY L  48
ALA L  49
 None
 0.69A 6hwdK-5fmgL:
28.5
6hwdL-5fmgL:
23.8		 6hwdK-5fmgL:
63.75
6hwdL-5fmgL:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.08A 6hwdK-5fmgI:
28.0
6hwdL-5fmgI:
23.9		 6hwdK-5fmgI:
18.78
6hwdL-5fmgI:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 0.94A 6hwdK-5fmgI:
28.0
6hwdL-5fmgI:
23.9		 6hwdK-5fmgI:
18.78
6hwdL-5fmgI:
17.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.91A 6hwdH-5fmgI:
28.7
6hwdN-5fmgI:
28.4		 6hwdH-5fmgI:
37.80
6hwdN-5fmgI:
17.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 12 THR I   1
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.52A 6hwdH-5fmgI:
28.7
6hwdN-5fmgI:
28.4		 6hwdH-5fmgI:
37.80
6hwdN-5fmgI:
17.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 ALA I  27
LYS I  33
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.83A 6hwdV-5fmgI:
30.2		 6hwdV-5fmgI:
37.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  27
CYH I  31
ALA I  46
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 ( 3.8A)
7F1  I 300 ( 3.8A)
None
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.72A 6hwdV-5fmgI:
30.2		 6hwdV-5fmgI:
37.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ALA I  49
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.76A 6hwdY-5fmgI:
16.9
6hwdZ-5fmgI:
23.7		 6hwdY-5fmgI:
18.78
6hwdZ-5fmgI:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ALA I  49
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-3.5A)
 0.58A 6hwdY-5fmgI:
16.9
6hwdZ-5fmgI:
23.7		 6hwdY-5fmgI:
18.78
6hwdZ-5fmgI:
17.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
ALA L  20
GLY L  47
GLY L  48
ALA L  49
 None
 0.54A 6hwdY-5fmgL:
16.8
6hwdZ-5fmgL:
23.8		 6hwdY-5fmgL:
63.75
6hwdZ-5fmgL:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		5 / 11 THR L   1
MET L  45
GLY L  47
GLY L  48
ALA L  49
 None
 0.69A 6hwdY-5fmgL:
16.8
6hwdZ-5fmgL:
23.8		 6hwdY-5fmgL:
63.75
6hwdZ-5fmgL:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 11 ALA I  20
THR I  21
ALA I  27
LYS I  33
GLY I  47
ASP J 138
 7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-4.7A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 1.09A 6hwdY-5fmgI:
16.9
6hwdZ-5fmgI:
23.7		 6hwdY-5fmgI:
18.78
6hwdZ-5fmgI:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
BETA3 PROTEASOME
SUBUNIT, PUTATIVE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		6 / 11 THR I   1
ALA I  20
THR I  21
ALA I  27
GLY I  47
ASP J 138
 7F1  I 300 (-2.7A)
7F1  I 300 (-3.6A)
None
7F1  I 300 ( 3.8A)
7F1  I 300 (-3.8A)
7F1  I 300 (-2.6A)
 0.95A 6hwdY-5fmgI:
16.9
6hwdZ-5fmgI:
23.7		 6hwdY-5fmgI:
18.78
6hwdZ-5fmgI:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 5fmg PROTEASOME SUBUNIT
ALPHA TYPE
PROTEASOME SUBUNIT
ALPHA TYPE
(Plasmodium
falciparum;
Plasmodium
falciparum) 		5 / 12 LEU C 175
THR C  34
ILE C  35
LEU C 135
LEU D  53
 None
 1.32A 6ie8A-5fmgC:
undetectable		 6ie8A-5fmgC:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 5fmg PROTEASOME SUBUNIT
BETA TYPE
(Plasmodium
falciparum) 		4 / 8 GLY I   5
LEU I 100
GLY I 101
LEU I 110
 None
 0.86A 6mdqA-5fmgI:
undetectable		 6mdqA-5fmgI:
16.43