SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5fmi BCL-2 HOMOLOGOUS
ANTAGONIST/KILLER
(Homo
sapiens) 		5 / 12 LEU A 140
PHE A 119
LEU A  97
ARG A  42
TYR A  38
 None
 1.24A 1kt5A-5fmiA:
undetectable		 1kt5A-5fmiA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5fmi BCL-2 HOMOLOGOUS
ANTAGONIST/KILLER
(Homo
sapiens) 		5 / 12 HIS A 141
VAL A 142
PHE A 150
ALA A 115
VAL A 158
 None
 1.22A 5n0rA-5fmiA:
undetectable		 5n0rA-5fmiA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5fmi BCL-2 HOMOLOGOUS
ANTAGONIST/KILLER
(Homo
sapiens) 		5 / 12 HIS A 141
VAL A 142
PHE A 150
ALA A 115
VAL A 158
 None
 1.21A 5n0wA-5fmiA:
undetectable		 5n0wA-5fmiA:
19.28