SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fmt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AJ6_A_NOVA1_1 (GYRASE)	5fmt	FLAGELLAR ASSOCIATED PROTEIN (Chlamydomonas reinhardtii)	5 / 9	GLU A 102 ARG A 93 ILE A 97 PRO A 94 THR A 106	None	1.36A	1aj6A-5fmtA: undetectable	1aj6A-5fmtA: 17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJL_A_SAMA200_0 (METHIONINE REPRESSOR PROTEIN METJ)	5fmt	FLAGELLAR ASSOCIATED PROTEIN (Chlamydomonas reinhardtii)	5 / 11	ALA A 92 PHE A 109 ARG A 115 LEU A 86 GLU A 88	None	1.26A	1mjlA-5fmtA: undetectable 1mjlB-5fmtA: undetectable	1mjlA-5fmtA: 19.01 1mjlB-5fmtA: 19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVR_A_URFA2001_1 (URIDINE PHOSPHORYLASE)	5fmt	FLAGELLAR ASSOCIATED PROTEIN (Chlamydomonas reinhardtii)	5 / 10	THR A 8 GLY A 114 PHE A 19 LEU A 110 LEU A 113	None	1.30A	3kvrA-5fmtA: undetectable	3kvrA-5fmtA: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVR_B_URFB2011_1 (URIDINE PHOSPHORYLASE)	5fmt	FLAGELLAR ASSOCIATED PROTEIN (Chlamydomonas reinhardtii)	5 / 10	THR A 8 GLY A 114 PHE A 19 LEU A 110 LEU A 113	None	1.29A	3kvrB-5fmtA: undetectable	3kvrB-5fmtA: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKX_A_198A1002_1 (ANDROGEN RECEPTOR)	5fmt	FLAGELLAR ASSOCIATED PROTEIN (Chlamydomonas reinhardtii)	5 / 12	LEU A 54 LEU A 113 VAL A 85 THR A 48 VAL A 18	None None SO4 A1131 ( 4.8A) None None	1.14A	4okxA-5fmtA: undetectable	4okxA-5fmtA: 21.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AJ6_A_NOVA1_1","GYRASE","5fmt","FLAGELLAR ASSOCIATED PROTEIN","Chlamydomonas reinhardtii",5,"GLU A 102;ARG A  93;ILE A  97;PRO A  94;THR A 106","None","1.36A","1aj6A-5fmtA:undetectable","1aj6A-5fmtA:17.78"],["1MJL_A_SAMA200_0","METHIONINE REPRESSOR PROTEIN METJ","5fmt","FLAGELLAR ASSOCIATED PROTEIN","Chlamydomonas reinhardtii",5,"ALA A  92;PHE A 109;ARG A 115;LEU A  86;GLU A  88","None","1.26A","1mjlA-5fmtA:undetectable;1mjlB-5fmtA:undetectable","1mjlA-5fmtA:19.01;1mjlB-5fmtA:19.01"],["3KVR_A_URFA2001_1","URIDINE PHOSPHORYLASE","5fmt","FLAGELLAR ASSOCIATED PROTEIN","Chlamydomonas reinhardtii",5,"THR A   8;GLY A 114;PHE A  19;LEU A 110;LEU A 113","None","1.30A","3kvrA-5fmtA:undetectable","3kvrA-5fmtA:16.89"],["3KVR_B_URFB2011_1","URIDINE PHOSPHORYLASE","5fmt","FLAGELLAR ASSOCIATED PROTEIN","Chlamydomonas reinhardtii",5,"THR A   8;GLY A 114;PHE A  19;LEU A 110;LEU A 113","None","1.29A","3kvrB-5fmtA:undetectable","3kvrB-5fmtA:16.89"],["4OKX_A_198A1002_1","ANDROGEN RECEPTOR","5fmt","FLAGELLAR ASSOCIATED PROTEIN","Chlamydomonas reinhardtii",5,"LEU A  54;LEU A 113;VAL A  85;THR A  48;VAL A  18","None;None;SO4 A1131 ( 4.8A);None;None","1.14A","4okxA-5fmtA:undetectable","4okxA-5fmtA:21.72"]]