SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 5fmu TRAF3-INTERACTING
PROTEIN 1
(Mus
musculus) 		5 / 11 VAL A  42
ILE A  17
LEU A  13
LEU A 107
LEU A 108
 None
 1.30A 2a15A-5fmuA:
undetectable		 2a15A-5fmuA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 5fmu TRAF3-INTERACTING
PROTEIN 1
(Mus
musculus) 		4 / 4 PHE A  72
LYS A  69
ILE A  39
THR A  54
 None
 1.48A 3ia4B-5fmuA:
undetectable		 3ia4B-5fmuA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 5fmu TRAF3-INTERACTING
PROTEIN 1
(Mus
musculus) 		3 / 3 ASN A   2
ALA A   4
ARG A   8
 None
 0.60A 5cvtB-5fmuA:
undetectable		 5cvtB-5fmuA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_B_ACTB1321_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT)		 5fmu TRAF3-INTERACTING
PROTEIN 1
(Mus
musculus) 		3 / 3 THR A  54
ASP A  55
ALA A  56
 None
 0.09A 5g5gB-5fmuA:
undetectable		 5g5gB-5fmuA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fmu TRAF3-INTERACTING
PROTEIN 1
(Mus
musculus) 		5 / 12 GLN A 109
ILE A  38
TYR A  34
LEU A  35
ILE A  77
 None
 1.17A 5y2tB-5fmuA:
undetectable		 5y2tB-5fmuA:
undetectable