SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5fmv RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE C
(Homo
sapiens) 		4 / 6 ASN A 468
ILE A 462
ASN A 434
THR A 421
 NAG  A1578 (-1.9A)
None
NAG  A1578 (-4.3A)
NAG  A1578 (-3.0A)
 1.23A 1h7xA-5fmvA:
undetectable		 1h7xA-5fmvA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5fmv RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE C
(Homo
sapiens) 		4 / 6 ASN A 468
ILE A 462
ASN A 434
THR A 421
 NAG  A1578 (-1.9A)
None
NAG  A1578 (-4.3A)
NAG  A1578 (-3.0A)
 1.24A 1h7xB-5fmvA:
undetectable		 1h7xB-5fmvA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5fmv RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE C
(Homo
sapiens) 		4 / 6 ASN A 468
ILE A 462
ASN A 434
THR A 421
 NAG  A1578 (-1.9A)
None
NAG  A1578 (-4.3A)
NAG  A1578 (-3.0A)
 1.24A 1h7xC-5fmvA:
undetectable		 1h7xC-5fmvA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5fmv RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE C
(Homo
sapiens) 		4 / 6 ASN A 468
ILE A 462
ASN A 434
THR A 421
 NAG  A1578 (-1.9A)
None
NAG  A1578 (-4.3A)
NAG  A1578 (-3.0A)
 1.23A 1h7xD-5fmvA:
undetectable		 1h7xD-5fmvA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5fmv RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE C
(Homo
sapiens) 		3 / 3 ASN A 372
HIS A 374
VAL A 235
 None
 0.79A 3elzB-5fmvA:
undetectable		 3elzB-5fmvA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5fmv RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE C
(Homo
sapiens) 		4 / 5 THR A 409
ILE A 408
LYS A 441
PHE A 476
 None
 1.35A 4acaC-5fmvA:
undetectable		 4acaC-5fmvA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 5fmv RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE C
(Homo
sapiens) 		4 / 8 ILE A 233
TYR A 237
VAL A 279
ASP A 227
 None
 1.00A 5vlmF-5fmvA:
undetectable		 5vlmF-5fmvA:
17.78