SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUD_A_SUEA1201_2 (NS3 PROTEASE, NS4A PROTEIN)	5fn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C (Homo sapiens)	4 / 4	PHE A 89 TYR A 156 ILE A 137 LEU A 106	None	1.46A	3sudA-5fn7A: undetectable	3sudA-5fn7A: 18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XO7_B_ASDB402_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2)	5fn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C (Homo sapiens)	4 / 7	TYR A 22 VAL A 53 ILE A 66 HIS A 159	None	1.24A	4xo7B-5fn7A: undetectable	4xo7B-5fn7A: 17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_F_CVIF301_1 (REGULATORY PROTEIN TETR)	5fn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C (Homo sapiens)	4 / 8	ILE A 18 TYR A 22 VAL A 64 ASP A 12	None	0.99A	5vlmF-5fn7A: undetectable	5vlmF-5fn7A: 17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C71_B_NCTB501_1 (AMINE OXIDASE)	5fn7	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C (Homo sapiens)	4 / 8	TYR A 123 THR A 162 TRP A 108 ASN A 110	None	1.02A	6c71B-5fn7A: undetectable	6c71B-5fn7A: 16.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3SUD_A_SUEA1201_2","NS3 PROTEASE, NS4A PROTEIN","5fn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C","Homo sapiens",4,"PHE A  89;TYR A 156;ILE A 137;LEU A 106","None","1.46A","3sudA-5fn7A:undetectable","3sudA-5fn7A:18.69"],["4XO7_B_ASDB402_1","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C2","5fn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C","Homo sapiens",4,"TYR A  22;VAL A  53;ILE A  66;HIS A 159","None","1.24A","4xo7B-5fn7A:undetectable","4xo7B-5fn7A:17.96"],["5VLM_F_CVIF301_1","REGULATORY PROTEIN TETR","5fn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C","Homo sapiens",4,"ILE A  18;TYR A  22;VAL A  64;ASP A  12","None","0.99A","5vlmF-5fn7A:undetectable","5vlmF-5fn7A:17.33"],["6C71_B_NCTB501_1","AMINE OXIDASE","5fn7","RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C","Homo sapiens",4,"TYR A 123;THR A 162;TRP A 108;ASN A 110","None","1.02A","6c71B-5fn7A:undetectable","6c71B-5fn7A:16.11"]]