SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fno'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.71A 1rjoA-5fnoA:
undetectable		 1rjoA-5fnoA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.64A 1rkyA-5fnoA:
undetectable		 1rkyA-5fnoA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 8 GLU A 426
TRP A 430
HIS A 296
ASP A 424
 None
 1.23A 1s3zA-5fnoA:
undetectable
1s3zB-5fnoA:
undetectable		 1s3zA-5fnoA:
15.77
1s3zB-5fnoA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.72A 1w2zA-5fnoA:
undetectable		 1w2zA-5fnoA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.69A 1w2zB-5fnoA:
undetectable		 1w2zB-5fnoA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.70A 1w2zD-5fnoA:
undetectable		 1w2zD-5fnoA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2002_1
(SERUM ALBUMIN)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 8 ARG A 557
ALA A 558
ALA A 412
LEU A 548
 None
 0.85A 2bxgA-5fnoA:
undetectable		 2bxgA-5fnoA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 10 ALA A 343
LEU A 484
LEU A 510
SER A 224
LEU A 491
 None
 1.40A 2ceoB-5fnoA:
undetectable		 2ceoB-5fnoA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.72A 2oqeA-5fnoA:
undetectable		 2oqeA-5fnoA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.73A 2oqeB-5fnoA:
undetectable		 2oqeB-5fnoA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.71A 2oqeC-5fnoA:
undetectable		 2oqeC-5fnoA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.72A 2oqeD-5fnoA:
undetectable		 2oqeD-5fnoA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.71A 2oqeF-5fnoA:
undetectable		 2oqeF-5fnoA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 ARG A 218
THR A 247
VAL A 249
 None
 0.94A 2qakA-5fnoA:
undetectable		 2qakA-5fnoA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TCT_A_CTCA222_0
(TETRACYCLINE
REPRESSOR)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 HIS A 487
SER A 481
GLN A 519
ILE A 143
SER A 148
 None
 1.15A 2tctA-5fnoA:
1.7		 2tctA-5fnoA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.67A 2w0qA-5fnoA:
undetectable		 2w0qA-5fnoA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.69A 2w0qB-5fnoA:
undetectable		 2w0qB-5fnoA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 7 TYR A 492
GLN A 519
ILE A 270
SER A 516
 None
 1.29A 2xz5A-5fnoA:
undetectable
2xz5B-5fnoA:
undetectable		 2xz5A-5fnoA:
19.34
2xz5B-5fnoA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 7 GLN A 519
ILE A 270
SER A 516
TYR A 492
 None
 1.26A 2xz5D-5fnoA:
undetectable
2xz5E-5fnoA:
undetectable		 2xz5D-5fnoA:
19.34
2xz5E-5fnoA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 ASP A 209
PHE A 272
PHE A 181
VAL A 249
ASN A 248
 None
 1.32A 2y01A-5fnoA:
undetectable		 2y01A-5fnoA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 GLN A 281
HIS A 284
HIS A 289
PHE A 342
LEU A 331
 None
MN  A 606 (-3.7A)
MN  A 606 (-3.4A)
None
None
 1.15A 3czvA-5fnoA:
undetectable
3czvB-5fnoA:
undetectable		 3czvA-5fnoA:
17.61
3czvB-5fnoA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 10 GLN A 281
HIS A 284
HIS A 289
PHE A 342
LEU A 331
 None
MN  A 606 (-3.7A)
MN  A 606 (-3.4A)
None
None
 1.22A 3dazA-5fnoA:
undetectable		 3dazA-5fnoA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 10 GLN A 281
HIS A 284
HIS A 289
PHE A 342
LEU A 331
 None
MN  A 606 (-3.7A)
MN  A 606 (-3.4A)
None
None
 1.18A 3dcsA-5fnoA:
undetectable		 3dcsA-5fnoA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.71A 3hiiA-5fnoA:
undetectable		 3hiiA-5fnoA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		3 / 3 HIS A 289
HIS A 284
HIS A 469
 MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
MN  A 606 (-3.3A)
 0.69A 3hiiB-5fnoA:
undetectable		 3hiiB-5fnoA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 GLN A 281
HIS A 284
HIS A 289
PHE A 342
LEU A 331
 None
MN  A 606 (-3.7A)
MN  A 606 (-3.4A)
None
None
 1.21A 3hkuA-5fnoA:
undetectable		 3hkuA-5fnoA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 LEU A 594
LEU A 538
MET A 541
ALA A 462
ILE A 402
 None
 1.14A 3ut5B-5fnoA:
undetectable		 3ut5B-5fnoA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 LEU A 594
LEU A 538
MET A 541
ALA A 462
ILE A 402
 None
 1.14A 3ut5D-5fnoA:
undetectable		 3ut5D-5fnoA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 11 GLN A 281
HIS A 284
HIS A 289
PHE A 342
LEU A 331
 None
MN  A 606 (-3.7A)
MN  A 606 (-3.4A)
None
None
 1.24A 3v2jA-5fnoA:
undetectable		 3v2jA-5fnoA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 8 GLN A 474
HIS A 469
HIS A 289
HIS A 284
 None
MN  A 606 (-3.3A)
MN  A 606 (-3.4A)
MN  A 606 (-3.7A)
 0.99A 3w6hA-5fnoA:
undetectable		 3w6hA-5fnoA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 8 VAL A 573
MET A 566
ILE A 569
GLU A 476
 None
 1.06A 4a97C-5fnoA:
undetectable		 4a97C-5fnoA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 8 VAL A 573
MET A 566
ILE A 569
GLU A 476
 None
 1.09A 4a97G-5fnoA:
undetectable		 4a97G-5fnoA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 HIS A 487
SER A 481
GLN A 519
ILE A 143
SER A 148
 None
 1.07A 4b3aA-5fnoA:
undetectable		 4b3aA-5fnoA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 5 LEU A 427
LEU A 454
MET A 313
TRP A 363
 None
 1.34A 4do3A-5fnoA:
undetectable		 4do3A-5fnoA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 11 GLN A 281
HIS A 284
HIS A 289
PHE A 342
LEU A 331
 None
MN  A 606 (-3.7A)
MN  A 606 (-3.4A)
None
None
 1.26A 4g0cA-5fnoA:
undetectable		 4g0cA-5fnoA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 8 ASN A 275
ALA A 225
SER A 224
ARG A 214
 None
 1.19A 4ijiF-5fnoA:
undetectable		 4ijiF-5fnoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 7 ASN A 275
ALA A 225
SER A 224
ARG A 214
 None
 1.17A 4ijiH-5fnoA:
undetectable		 4ijiH-5fnoA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 9 PHE A 391
ALA A 593
LEU A 594
GLY A 395
ALA A 320
 None
 1.47A 4l6va-5fnoA:
undetectable
4l6vf-5fnoA:
undetectable		 4l6va-5fnoA:
23.53
4l6vf-5fnoA:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 LEU A 427
VAL A 421
PHE A 409
LEU A 547
LEU A 316
 None
 1.45A 4o8fB-5fnoA:
undetectable		 4o8fB-5fnoA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2G_B_CTCB222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 HIS A 487
SER A 481
VAL A 478
ILE A 143
SER A 148
 None
 1.45A 4v2gB-5fnoA:
undetectable		 4v2gB-5fnoA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 6 SER A 123
LEU A 124
ASP A 125
LEU A 507
 None
 0.73A 4wozA-5fnoA:
undetectable
4wozB-5fnoA:
undetectable		 4wozA-5fnoA:
20.20
4wozB-5fnoA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 LEU A 594
LEU A 538
MET A 541
ALA A 462
ILE A 402
 None
 1.16A 4x1yB-5fnoA:
undetectable		 4x1yB-5fnoA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 ILE A 291
GLY A 361
TYR A 287
HIS A 460
GLU A 456
 None
 1.35A 5igwA-5fnoA:
undetectable		 5igwA-5fnoA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 6 VAL A 372
LEU A 398
SER A 396
ARG A 403
 None
 0.93A 5jw1A-5fnoA:
0.9		 5jw1A-5fnoA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_C_CVIC301_0
(REGULATORY PROTEIN
TETR)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 12 ALA A 462
ARG A 453
TYR A 414
ASP A 442
PHE A 443
 None
 1.44A 5vlmC-5fnoA:
undetectable		 5vlmC-5fnoA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		5 / 10 GLY A 280
LEU A 277
VAL A 164
ALA A 480
LEU A 523
 None
 1.15A 6czmA-5fnoA:
undetectable
6czmC-5fnoA:
undetectable		 6czmA-5fnoA:
21.32
6czmC-5fnoA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 6 GLY A 482
PHE A 278
PHE A 338
PHE A 332
 None
 0.98A 6h7lA-5fnoA:
undetectable		 6h7lA-5fnoA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5fno MANGANESE
LIPOXYGENASE
(Magnaporthe
oryzae) 		4 / 6 GLY A 482
PHE A 278
PHE A 338
PHE A 332
 None
 0.98A 6h7lB-5fnoA:
1.7		 6h7lB-5fnoA:
9.27