SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fnx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_G_SAMG226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	5fnx	POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D (Solanum tuberosum)	5 / 12	LEU A 172 GLY A 34 VAL A 59 PRO A 61 GLY A 30	None	0.87A	3ku1G-5fnxA: undetectable	3ku1G-5fnxA: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_H_SAMH226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	5fnx	POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D (Solanum tuberosum)	5 / 12	LEU A 172 GLY A 34 VAL A 59 PRO A 61 GLY A 30	None	0.98A	3ku1H-5fnxA: undetectable	3ku1H-5fnxA: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_C_ACHC323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	5fnx	POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D (Solanum tuberosum)	4 / 8	PHE A 108 ASN A 43 GLU A 114 PHE A 53	None	0.87A	3rqwC-5fnxA: undetectable 3rqwD-5fnxA: undetectable	3rqwC-5fnxA: 19.52 3rqwD-5fnxA: 19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RQW_J_ACHJ323_0 (ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI)	5fnx	POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D (Solanum tuberosum)	4 / 8	GLU A 114 PHE A 53 PHE A 108 ASN A 43	None	0.86A	3rqwF-5fnxA: undetectable 3rqwJ-5fnxA: undetectable	3rqwF-5fnxA: 19.52 3rqwJ-5fnxA: 19.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3KU1_G_SAMG226_0","SAM-DEPENDENT METHYLTRANSFERASE","5fnx","POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D","Solanum tuberosum",5,"LEU A 172;GLY A  34;VAL A  59;PRO A  61;GLY A  30","None","0.87A","3ku1G-5fnxA:undetectable","3ku1G-5fnxA:21.89"],["3KU1_H_SAMH226_0","SAM-DEPENDENT METHYLTRANSFERASE","5fnx","POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D","Solanum tuberosum",5,"LEU A 172;GLY A  34;VAL A  59;PRO A  61;GLY A  30","None","0.98A","3ku1H-5fnxA:undetectable","3ku1H-5fnxA:21.89"],["3RQW_C_ACHC323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","5fnx","POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D","Solanum tuberosum",4,"PHE A 108;ASN A  43;GLU A 114;PHE A  53","None","0.87A","3rqwC-5fnxA:undetectable;3rqwD-5fnxA:undetectable","3rqwC-5fnxA:19.52;3rqwD-5fnxA:19.52"],["3RQW_J_ACHJ323_0","ELIC PENTAMERIC LIGAND GATED ION CHANNEL FROM ERWINIA CHRYSANTHEMI","5fnx","POTATO STI-KUNITZ BI-FUNCTIONAL INHIBITOR E3AD_N19D","Solanum tuberosum",4,"GLU A 114;PHE A  53;PHE A 108;ASN A  43","None","0.86A","3rqwF-5fnxA:undetectable;3rqwJ-5fnxA:undetectable","3rqwF-5fnxA:19.52;3rqwJ-5fnxA:19.52"]]