SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fo1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 11 PHE A  84
ARG A  77
ILE A  71
LEU A  80
ALA A  81
 None
 1.28A 1jb0B-5fo1A:
undetectable		 1jb0B-5fo1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 9 SER A 253
GLU A 268
ARG A 292
LEU A 303
ASP A 310
 None
 0.85A 1nb9A-5fo1A:
14.2		 1nb9A-5fo1A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 10 LEU A 139
LEU A  34
VAL A 151
GLY A 123
ALA A 124
 None
 0.97A 1pxxA-5fo1A:
undetectable		 1pxxA-5fo1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 9 LEU A 139
LEU A  34
VAL A 151
GLY A 123
ALA A 124
 None
 0.99A 1pxxB-5fo1A:
undetectable		 1pxxB-5fo1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 LEU A 139
LEU A  34
VAL A 151
GLY A 123
ALA A 124
 None
 0.99A 1pxxC-5fo1A:
undetectable		 1pxxC-5fo1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 10 LEU A 139
LEU A  34
VAL A 151
GLY A 123
ALA A 124
 None
 0.98A 1pxxD-5fo1A:
undetectable		 1pxxD-5fo1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		4 / 5 GLY A  70
ILE A  71
VAL A  23
SER A 164
 None
None
PPV  A1339 (-4.0A)
PPV  A1339 (-3.2A)
 1.15A 1rs7A-5fo1A:
undetectable		 1rs7A-5fo1A:
19.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 11 VAL A 224
GLU A 268
ARG A 292
LEU A 303
ASP A 310
 None
 0.72A 1t6zA-5fo1A:
26.5		 1t6zA-5fo1A:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 11 VAL A 224
GLU A 268
ARG A 292
LEU A 303
ASP A 310
 None
 0.65A 1t6zB-5fo1A:
27.2		 1t6zB-5fo1A:
33.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 HIS A  28
GLY A  30
HIS A  31
GLY A 123
LEU A 155
 PPV  A1339 (-3.7A)
None
PPV  A1339 (-3.8A)
None
None
 0.78A 2x1lB-5fo1A:
3.7		 2x1lB-5fo1A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 THR A 208
ILE A 252
ASN A 241
MET A 242
LEU A 318
 None
 1.17A 3a51D-5fo1A:
undetectable		 3a51D-5fo1A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A 174
ASP A  25
GLY A  26
ARG A 185
ASN A 180
 None
 1.28A 3jzjA-5fo1A:
undetectable		 3jzjA-5fo1A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 11 PHE A  84
ARG A  77
ILE A  71
LEU A  80
ALA A  81
 None
 1.28A 3pcqB-5fo1A:
undetectable		 3pcqB-5fo1A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		4 / 6 GLY A  70
ILE A  71
VAL A  23
SER A 164
 None
None
PPV  A1339 (-4.0A)
PPV  A1339 (-3.2A)
 1.09A 4kcnA-5fo1A:
undetectable		 4kcnA-5fo1A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 VAL A 254
SER A 266
VAL A 291
PHE A 287
LEU A 272
 None
 1.24A 4nc3A-5fo1A:
undetectable		 4nc3A-5fo1A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A  85
ILE A  50
SER A  17
ASN A  36
THR A  20
 None
 1.30A 4pooA-5fo1A:
undetectable		 4pooA-5fo1A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 GLY A  30
HIS A  31
LEU A  34
GLY A 123
LEU A 155
 None
PPV  A1339 (-3.8A)
None
None
None
 1.11A 5hg0B-5fo1A:
12.5		 5hg0B-5fo1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 HIS A  28
GLY A  30
HIS A  31
LEU A  34
GLY A 123
 PPV  A1339 (-3.7A)
None
PPV  A1339 (-3.8A)
None
None
 0.44A 5hg0B-5fo1A:
12.5		 5hg0B-5fo1A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		3 / 3 VAL A 107
GLN A 141
CYH A 143
 None
 0.58A 5icxA-5fo1A:
undetectable
5icxE-5fo1A:
undetectable		 5icxA-5fo1A:
24.77
5icxE-5fo1A:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 TYR A 188
THR A  73
GLU A  76
GLY A 191
VAL A 283
 None
SO4  A1340 (-4.1A)
None
None
None
 1.42A 5jo9A-5fo1A:
2.8		 5jo9A-5fo1A:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 9 ILE A  21
LEU A  34
GLY A 123
PHE A 126
ALA A  37
 None
 1.41A 5x66C-5fo1A:
undetectable		 5x66C-5fo1A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 12 LEU A 219
VAL A 267
ILE A 252
LEU A  80
LEU A 183
 None
 0.93A 5ycnA-5fo1A:
undetectable		 5ycnA-5fo1A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		4 / 5 VAL A 311
THR A 314
LEU A 204
LEU A 303
 None
 0.96A 6bqgA-5fo1A:
undetectable		 6bqgA-5fo1A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 9 PHE A  84
VAL A  27
HIS A  28
ILE A  50
ARG A  77
 None
None
PPV  A1339 (-3.7A)
None
None
 1.33A 6c2mC-5fo1A:
undetectable		 6c2mC-5fo1A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		4 / 7 ASN A  36
ALA A  37
LYS A  41
GLU A  44
 None
 1.00A 6ci6A-5fo1A:
undetectable		 6ci6A-5fo1A:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		4 / 5 GLY A  22
HIS A  31
SER A 163
SER A 164
 PPV  A1339 ( 3.8A)
PPV  A1339 (-3.8A)
PPV  A1339 (-4.7A)
PPV  A1339 (-3.2A)
 0.49A 6jmjA-5fo1A:
10.7		 6jmjA-5fo1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		5 / 7 GLY A  22
PHE A  24
HIS A  31
SER A 163
SER A 164
 PPV  A1339 ( 3.8A)
PPV  A1339 (-4.7A)
PPV  A1339 (-3.8A)
PPV  A1339 (-4.7A)
PPV  A1339 (-3.2A)
 0.75A 6jnhA-5fo1A:
10.7		 6jnhA-5fo1A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5fo1 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBF
(Corynebacterium
ammoniagenes) 		4 / 6 GLY A  22
HIS A  31
SER A 163
SER A 164
 PPV  A1339 ( 3.8A)
PPV  A1339 (-3.8A)
PPV  A1339 (-4.7A)
PPV  A1339 (-3.2A)
 0.53A 6jogA-5fo1A:
10.8		 6jogA-5fo1A:
22.81