SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fo3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		3 / 3 TRP A  11
PHE A  49
TRP A   9
 None
 1.24A 1r15C-5fo3A:
undetectable		 1r15C-5fo3A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		3 / 3 TRP A  11
PHE A  49
TRP A   9
 None
 1.23A 1r15F-5fo3A:
undetectable		 1r15F-5fo3A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		3 / 3 TRP A  11
PHE A  49
TRP A   9
 None
 1.25A 1r15G-5fo3A:
undetectable		 1r15G-5fo3A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		3 / 3 TRP A  11
PHE A  49
TRP A   9
 None
 1.22A 1r15H-5fo3A:
undetectable		 1r15H-5fo3A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		5 / 10 GLN A 142
VAL A 145
LEU A 140
LEU A 117
THR A 120
 None
 1.23A 1rj6A-5fo3A:
undetectable		 1rj6A-5fo3A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		5 / 10 GLN A 142
VAL A 145
LEU A 140
LEU A 117
THR A 120
 None
 1.19A 1rj6B-5fo3A:
undetectable		 1rj6B-5fo3A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		6 / 12 GLN A 142
VAL A 145
ILE A 147
VAL A 146
LEU A 117
THR A 120
 None
 1.18A 3fw3A-5fo3A:
undetectable		 3fw3A-5fo3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		5 / 12 GLN A 142
VAL A 145
ILE A 147
LEU A 117
THR A 120
 None
 0.95A 3fw3B-5fo3A:
undetectable		 3fw3B-5fo3A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		3 / 3 PRO A  90
LEU A  88
GLN A  91
 None
 0.55A 3hznG-5fo3A:
undetectable
3hznH-5fo3A:
undetectable		 3hznG-5fo3A:
23.14
3hznH-5fo3A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		4 / 5 GLY A 110
ASP A 111
GLN A 142
MET A 152
 None
 1.41A 3qx3A-5fo3A:
undetectable		 3qx3A-5fo3A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 5fo3 CELL DIVISION
PROTEIN ZAPC
(Escherichia
coli) 		4 / 7 GLN A 142
VAL A 145
LEU A 117
THR A 120
 None
 0.95A 5m78A-5fo3A:
undetectable		 5m78A-5fo3A:
15.64