SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 12 PHE A 391
VAL A 283
ILE A 297
ASN A 529
LEU A 539
 None
 1.10A 1fm4A-5fodA:
undetectable		 1fm4A-5fodA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_1
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 4 SER A 296
SER A 300
LEU A 417
PHE A 363
 None
 1.21A 1r5lA-5fodA:
undetectable		 1r5lA-5fodA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 6 ILE A 377
PRO A 468
LEU A 470
ILE A 443
 None
 0.81A 2q83B-5fodA:
undetectable		 2q83B-5fodA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 12 PHE A 391
GLY A 393
ILE A 390
VAL A 283
PHE A 289
 None
 1.19A 2zzmA-5fodA:
undetectable		 2zzmA-5fodA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 12 PHE A 391
GLY A 393
ILE A 390
VAL A 283
PHE A 289
 None
 1.24A 2zznA-5fodA:
undetectable		 2zznA-5fodA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 11 PHE A 683
CYH A 453
ILE A 467
SER A 457
LEU A 680
 None
 1.23A 3a9eB-5fodA:
undetectable		 3a9eB-5fodA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 11 VAL A 571
GLY A 403
THR A 543
ILE A 545
THR A 395
 None
 1.41A 3bexC-5fodA:
undetectable
3bexD-5fodA:
undetectable		 3bexC-5fodA:
20.61
3bexD-5fodA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 11 THR A 395
VAL A 571
GLY A 403
THR A 543
ILE A 545
 None
 1.41A 3bexE-5fodA:
undetectable
3bexF-5fodA:
undetectable		 3bexE-5fodA:
20.61
3bexF-5fodA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 11 VAL A 571
GLY A 403
THR A 543
ILE A 545
THR A 395
 None
 1.40A 3bf1E-5fodA:
undetectable
3bf1F-5fodA:
undetectable		 3bf1E-5fodA:
20.61
3bf1F-5fodA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 5 PRO A 555
ILE A 553
TYR A 406
TYR A 552
 None
 1.15A 3d9lA-5fodA:
undetectable
3d9lY-5fodA:
undetectable		 3d9lA-5fodA:
18.66
3d9lY-5fodA:
3.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 6 PHE A 391
PHE A 536
THR A 541
VAL A 283
 None
 1.25A 3lb3A-5fodA:
undetectable		 3lb3A-5fodA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 5 GLU A 540
LEU A 539
GLN A 602
GLY A 538
 None
 1.25A 3pp1A-5fodA:
undetectable		 3pp1A-5fodA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 6 GLY A 566
LEU A 278
TYR A 685
GLU A 687
 None
 0.97A 3w9tB-5fodA:
undetectable		 3w9tB-5fodA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 6 GLY A 566
LEU A 278
TYR A 685
GLU A 687
 None
 0.97A 3w9tE-5fodA:
undetectable		 3w9tE-5fodA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 6 GLY A 566
LEU A 278
TYR A 685
GLU A 687
 None
 0.97A 3w9tF-5fodA:
undetectable		 3w9tF-5fodA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MF6_A_BEZA303_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 5 PRO A 448
PHE A 683
ASN A 449
TYR A 451
 None
 1.42A 4mf6A-5fodA:
undetectable		 4mf6A-5fodA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		5 / 12 SER A 457
LEU A 461
ILE A 390
ILE A 567
GLY A 566
 None
 1.00A 4y8wC-5fodA:
undetectable		 4y8wC-5fodA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 5 GLU A 687
GLY A 566
SER A 394
GLY A 393
 None
 1.08A 5kprA-5fodA:
undetectable		 5kprA-5fodA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 5fod LEUCYL-TRNA
SYNTHETASE
(Plasmodium
falciparum) 		4 / 8 LEU A 278
TYR A 685
GLU A 687
ASN A 456
 None
 1.22A 6c71B-5fodA:
undetectable		 6c71B-5fodA:
11.34