SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5foh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
3 / 3 THR A  46
THR A  47
PRO A  23
None
0.81A 1a7yA-5fohA:
undetectable
1a7yA-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 4 THR A  46
PRO A  48
THR A  47
PRO A  23
None
1.09A 1dsdC-5fohA:
undetectable
1dsdC-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC2_0
(ACTINOMYCIN D)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 4 THR A  47
PRO A  23
THR A  46
PRO A  48
None
1.15A 1dsdC-5fohA:
undetectable
1dsdC-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 4 THR A  46
PRO A  48
THR A  47
PRO A  23
None
1.09A 1dsdC-5fohA:
undetectable
1dsdC-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSD_C_DVAC8_0
(ACTINOMYCIN D)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 4 THR A  47
PRO A  23
THR A  46
PRO A  48
None
1.15A 1dsdC-5fohA:
undetectable
1dsdC-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
3 / 3 THR A  46
THR A  47
PRO A  23
None
0.84A 1i3wF-5fohA:
undetectable
1i3wF-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
3 / 3 THR A  46
THR A  47
PRO A  23
None
0.79A 1qfiA-5fohA:
undetectable
1qfiA-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVU_A_PRLA196_0
(TRANSCRIPTIONAL
REGULATOR QACR)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
5 / 6 LEU A  86
GLU A 110
THR A 211
TYR A 212
TYR A 192
None
None
MAN  A1224 (-3.3A)
None
None
1.45A 1qvuA-5fohA:
undetectable
1qvuA-5fohA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
3 / 3 THR A  46
THR A  47
PRO A  23
None
0.82A 1unjF-5fohA:
undetectable
1unjF-5fohA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 6 ILE A 188
PRO A  84
LEU A 199
ILE A 150
None
0.96A 2q83B-5fohA:
undetectable
2q83B-5fohA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
5 / 11 PHE A 106
VAL A 173
ILE A 172
TYR A 143
VAL A  92
None
1.43A 2vcdA-5fohA:
undetectable
2vcdA-5fohA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 6 LEU A 145
TYR A 143
ALA A  95
LEU A  89
None
1.15A 3rd0A-5fohA:
undetectable
3rd0A-5fohA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 5 HIS A   1
HIS A  81
GLN A 162
TYR A 164
CU  A1226 ( 3.0A)
CU  A1226 ( 3.3A)
SO4  A1227 ( 3.3A)
None
0.64A 4gboA-5fohA:
8.6
4gboA-5fohA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 5 HIS A   1
HIS A  81
GLN A 162
TYR A 164
CU  A1226 ( 3.0A)
CU  A1226 ( 3.3A)
SO4  A1227 ( 3.3A)
None
0.85A 4gboB-5fohA:
8.6
4gboB-5fohA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 5 HIS A   1
HIS A 153
GLN A 162
TYR A 164
CU  A1226 ( 3.0A)
SO4  A1227 (-4.1A)
SO4  A1227 ( 3.3A)
None
1.03A 4gboB-5fohA:
8.6
4gboB-5fohA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
3 / 3 TYR A 212
GLY A  83
PRO A  84
None
0.72A 4qwpA-5fohA:
undetectable
4qwpA-5fohA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 5 TYR A 212
TYR A 192
GLU A 148
LEU A 199
None
1.30A 4qztB-5fohA:
0.5
4qztB-5fohA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 5 HIS A   1
HIS A  81
GLN A 162
TYR A 164
CU  A1226 ( 3.0A)
CU  A1226 ( 3.3A)
SO4  A1227 ( 3.3A)
None
0.62A 5uizA-5fohA:
8.6
5uizA-5fohA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_B_CUB301_0
(AA10A)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 4 HIS A   1
HIS A  81
GLN A 162
TYR A 164
CU  A1226 ( 3.0A)
CU  A1226 ( 3.3A)
SO4  A1227 ( 3.3A)
None
0.84A 5uizB-5fohA:
8.7
5uizB-5fohA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_B_CUB301_0
(AA10A)
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa)
4 / 4 HIS A   1
HIS A 153
GLN A 162
TYR A 164
CU  A1226 ( 3.0A)
SO4  A1227 (-4.1A)
SO4  A1227 ( 3.3A)
None
1.04A 5uizB-5fohA:
8.7
5uizB-5fohA:
22.04