SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 ARG A  73
GLY A 643
ASP A 667
 None
 0.59A 1kf6A-5fokA:
undetectable
1kf6B-5fokA:
undetectable		 1kf6A-5fokA:
22.28
1kf6B-5fokA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 388
SER A 377
GLY A 409
THR A 408
 None
 1.19A 2f7fA-5fokA:
undetectable		 2f7fA-5fokA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 137
SER A 144
SER A 133
ASP A 107
THR A 136
 None
 1.11A 2hmaA-5fokA:
undetectable		 2hmaA-5fokA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 6 ASP A  70
ARG A  73
THR A 645
ASP A 667
 None
 1.18A 2j2pE-5fokA:
undetectable
2j2pF-5fokA:
undetectable		 2j2pE-5fokA:
16.71
2j2pF-5fokA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 613
ASN A 616
THR A 621
 None
 0.60A 2pymB-5fokA:
undetectable		 2pymB-5fokA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 5 ASN A 189
THR A 281
SER A 227
ARG A 283
 None
 1.46A 3hlwB-5fokA:
undetectable		 3hlwB-5fokA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 THR A 658
SER A 657
ARG A 248
 None
 0.80A 3phnA-5fokA:
undetectable		 3phnA-5fokA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 8 ARG A 606
GLU A 604
GLU A 614
LYS A 611
 None
 1.24A 4bqfB-5fokA:
undetectable		 4bqfB-5fokA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4jksA-5fokA:
undetectable		 4jksA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4jksB-5fokA:
undetectable		 4jksB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4jkuB-5fokA:
undetectable		 4jkuB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4k8cA-5fokA:
undetectable		 4k8cA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4k8cB-5fokA:
undetectable		 4k8cB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4k8kA-5fokA:
undetectable		 4k8kA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4k8kB-5fokA:
undetectable		 4k8kB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.02A 4k8pB-5fokA:
undetectable		 4k8pB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4k8tB-5fokA:
undetectable		 4k8tB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4k9cA-5fokA:
undetectable		 4k9cA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4k9iB-5fokA:
undetectable		 4k9iB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4kadA-5fokA:
undetectable		 4kadA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4kahA-5fokA:
undetectable		 4kahA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4kalB-5fokA:
undetectable		 4kalB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4kanA-5fokA:
undetectable		 4kanA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4kbeB-5fokA:
undetectable		 4kbeB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 6 SER A  36
GLY A 143
ASP A 103
GLY A 132
 None
 0.95A 4koeA-5fokA:
undetectable
4koeB-5fokA:
undetectable
4koeC-5fokA:
undetectable		 4koeA-5fokA:
21.39
4koeB-5fokA:
21.39
4koeC-5fokA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 6 SER A  38
GLY A 143
ASP A 103
GLY A 132
 None
 0.77A 4koeA-5fokA:
undetectable
4koeB-5fokA:
undetectable
4koeC-5fokA:
undetectable		 4koeA-5fokA:
21.39
4koeB-5fokA:
21.39
4koeC-5fokA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 7 SER A  38
GLY A 143
ASP A 103
GLY A 132
 None
 0.77A 4koeA-5fokA:
undetectable
4koeB-5fokA:
undetectable
4koeD-5fokA:
undetectable		 4koeA-5fokA:
21.39
4koeB-5fokA:
21.39
4koeD-5fokA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 PRO A 253
TYR A 651
GLY A 652
ASN A 653
ILE A 660
 None
 1.39A 4kotA-5fokA:
undetectable		 4kotA-5fokA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.05A 4lbgA-5fokA:
undetectable		 4lbgA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4lbgB-5fokA:
undetectable		 4lbgB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4lbxA-5fokA:
undetectable		 4lbxA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.03A 4lbxB-5fokA:
undetectable		 4lbxB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4lc4A-5fokA:
undetectable		 4lc4A-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4lc4B-5fokA:
undetectable		 4lc4B-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.05A 4lcaA-5fokA:
undetectable		 4lcaA-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  78
GLY A  77
ASN A 625
GLU A 581
THR A 645
 None
 1.04A 4lcaB-5fokA:
undetectable		 4lcaB-5fokA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 5 TYR A 325
GLY A 393
ASP A 405
VAL A 203
 None
 1.15A 4nkvD-5fokA:
undetectable		 4nkvD-5fokA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 7 PHE A  80
ALA A  69
ILE A  55
LEU A 145
 None
 0.95A 4uymA-5fokA:
undetectable		 4uymA-5fokA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 7 PHE A  80
ALA A  69
ILE A  55
LEU A 145
 None
 1.03A 4uymB-5fokA:
undetectable		 4uymB-5fokA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 4 ASN A 121
SER A 227
ALA A 211
VAL A 210
 None
None
None
C8E  A1722 ( 4.7A)
 1.01A 4x1kC-5fokA:
undetectable		 4x1kC-5fokA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 9 ALA A  71
GLN A 115
LEU A 106
LEU A  68
LEU A 147
 None
 1.45A 4x30A-5fokA:
undetectable		 4x30A-5fokA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 143
ASP A 103
GLY A 132
SER A  36
 None
 0.94A 4z53A-5fokA:
undetectable
4z53B-5fokA:
undetectable		 4z53A-5fokA:
23.67
4z53B-5fokA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 143
ASP A 103
GLY A 132
SER A  38
 None
 0.76A 4z53A-5fokA:
undetectable
4z53B-5fokA:
undetectable		 4z53A-5fokA:
23.67
4z53B-5fokA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 143
ASP A 103
GLY A 132
SER A  36
 None
 0.95A 4z53A-5fokA:
undetectable
4z53B-5fokA:
undetectable		 4z53A-5fokA:
23.67
4z53B-5fokA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 143
ASP A 103
GLY A 132
SER A  38
 None
 0.74A 4z53A-5fokA:
undetectable
4z53B-5fokA:
undetectable		 4z53A-5fokA:
23.67
4z53B-5fokA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 480
THR A 482
THR A 500
 None
 0.53A 5aoxB-5fokA:
undetectable		 5aoxB-5fokA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 480
THR A 482
THR A 500
 None
 0.62A 5aoxE-5fokA:
undetectable		 5aoxE-5fokA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 257
ASP A 314
PRO A 312
SER A 698
TYR A 697
 None
 1.03A 5hfjD-5fokA:
undetectable		 5hfjD-5fokA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 217
ASP A 219
GLY A 181
ILE A 180
 None
 0.66A 5kr1B-5fokA:
undetectable		 5kr1B-5fokA:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 4 ASN A 189
SER A 227
ALA A 211
VAL A 210
 None
None
None
C8E  A1722 ( 4.7A)
 0.94A 5nm5A-5fokA:
undetectable		 5nm5A-5fokA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 306
ASN A 332
ASP A 413
 C8E  A1725 (-4.4A)
None
None
 0.84A 5vopB-5fokA:
undetectable		 5vopB-5fokA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 THR A 402
THR A 396
ARG A 326
 None
 1.06A 5wm2A-5fokA:
undetectable		 5wm2A-5fokA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		3 / 3 MET A 701
ASP A 314
ARG A 270
 None
 1.08A 5z6jA-5fokA:
undetectable		 5z6jA-5fokA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 652
ASN A 653
SER A 254
ARG A 248
 None
 1.19A 6dwdA-5fokA:
undetectable
6dwdC-5fokA:
undetectable		 6dwdA-5fokA:
21.56
6dwdC-5fokA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_1
(-)		 5fok IRON TRANSPORT OUTER
MEMBRANE RECEPTOR
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  66
SER A 149
HIS A 193
PHE A 120
VAL A 205
 None
 1.44A 6gnfC-5fokA:
undetectable		 6gnfC-5fokA:
20.72