SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5foz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		5 / 11 VAL B 157
LEU B 188
SER B 184
PHE B 177
THR B 173
 None
 1.19A 1mmtA-5fozB:
undetectable		 1mmtA-5fozB:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 5 TYR B 360
SER B 394
THR B 401
ASN B 354
 None
 1.11A 1yvpA-5fozB:
undetectable		 1yvpA-5fozB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 TYR B 360
SER B 394
THR B 401
ASN B 354
 None
 1.05A 1yvpB-5fozB:
undetectable		 1yvpB-5fozB:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AXN_A_EDTA737_0
(6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE 3
(6PF-2-K/FRU-
2,6-P2ASE
BRAIN/PLACENTA-TYPE
ISOZYME) (IPFK-2)
[INCLUDES: 6-
PHOSPHOFRUCTO-2-KINA
SE (EC 2.7.1.105)
FRUCTOSE-2,6-BISPHO
SPHATASE (EC
3.1.3.46)])		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 GLY B 312
ARG B 332
THR B 337
ARG B 388
TYR B 418
 None
 1.43A 2axnA-5fozB:
undetectable		 2axnA-5fozB:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP B  77
TYR B  76
LYS B  45
 None
 1.21A 2othA-5fozB:
undetectable		 2othA-5fozB:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 5 PRO B 109
ILE B 120
ARG B 122
ASP B 106
 None
 1.38A 2rhmB-5fozB:
undetectable		 2rhmB-5fozB:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 8 GLY B  92
ILE B 243
VAL B 104
TYR B 124
 None
 0.79A 2yoeB-5fozB:
undetectable
2yoeC-5fozB:
undetectable		 2yoeB-5fozB:
21.27
2yoeC-5fozB:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_A_DIFA1_1
(TRANSTHYRETIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 LEU B 164
ALA B 190
LEU B 188
SER B 159
 None
 0.96A 3cfqA-5fozB:
undetectable		 3cfqA-5fozB:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 ILE B  96
ALA B  97
ASN B 193
ILE B  37
LEU B  44
 None
 1.10A 3dzuA-5fozB:
undetectable		 3dzuA-5fozB:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		5 / 10 ILE B 392
PHE B 429
ILE B 285
LEU B 406
HIS B 409
 None
 1.27A 3qgzA-5fozB:
undetectable		 3qgzA-5fozB:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		5 / 9 GLY B 308
ASN B 416
GLY B 312
TYR B 418
ASP B 310
 None
 1.21A 3ztvA-5fozB:
undetectable		 3ztvA-5fozB:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP B 100
ARG B  99
ASP B  80
 None
 0.87A 4fp9C-5fozB:
undetectable		 4fp9C-5fozB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		3 / 3 ASP B 100
ARG B  99
ASP B  80
 None
 0.79A 4fp9F-5fozB:
undetectable		 4fp9F-5fozB:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG B 388
VAL B 385
PHE B 311
GLU B 267
 None
 1.49A 4jsfA-5fozB:
undetectable
4jsfB-5fozB:
undetectable		 4jsfA-5fozB:
21.65
4jsfB-5fozB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 8 SER B  56
ASP B 100
ASP B 101
TYR B  72
 None
 1.31A 4qb9D-5fozB:
undetectable		 4qb9D-5fozB:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU B 170
GLN B 134
ILE B 119
ILE B  96
PHE B 132
 None
 0.97A 4rp8C-5fozB:
undetectable		 4rp8C-5fozB:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 PHE B 311
GLU B 267
ARG B 388
VAL B 385
 None
 1.48A 4v3wA-5fozB:
undetectable
4v3wB-5fozB:
undetectable		 4v3wA-5fozB:
21.65
4v3wB-5fozB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ALA B 390
ARG B 288
GLY B 290
GLU B 343
 None
 0.97A 5btgA-5fozB:
undetectable
5btgB-5fozB:
undetectable
5btgC-5fozB:
undetectable		 5btgA-5fozB:
21.60
5btgB-5fozB:
18.76
5btgC-5fozB:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 SER B 335
GLY B 290
ARG B 344
GLY B 342
 None
 0.85A 5cdnR-5fozB:
undetectable
5cdnS-5fozB:
undetectable		 5cdnR-5fozB:
20.86
5cdnS-5fozB:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		5 / 12 LEU B 406
PHE B 423
PHE B 429
GLU B 287
ALA B 364
 None
 1.37A 5ieoA-5fozB:
2.8		 5ieoA-5fozB:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 6 ARG B 388
VAL B 385
PHE B 311
GLU B 267
 None
 1.46A 5unvA-5fozB:
undetectable
5unvB-5fozB:
undetectable		 5unvA-5fozB:
21.65
5unvB-5fozB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 7 ARG B 388
VAL B 385
PHE B 311
GLU B 267
 None
 1.45A 5vujA-5fozB:
undetectable
5vujB-5fozB:
undetectable		 5vujA-5fozB:
21.65
5vujB-5fozB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 5 TYR B 150
VAL B 104
PHE B 146
GLY B 136
 None
 1.43A 6hd4A-5fozB:
undetectable		 6hd4A-5fozB:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5foz LARVICIDAL TOXIN
PROTEIN
(Lysinibacillus
sphaericus) 		4 / 8 TYR B 265
ALA B 366
VAL B 385
ARG B 367
 None
 1.04A 6hu9a-5fozB:
undetectable
6hu9e-5fozB:
undetectable		 6hu9a-5fozB:
22.30
6hu9e-5fozB:
14.06