SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fp2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 7 ASN A 373
GLY A 145
ALA A 412
ILE A 410
 None
 0.73A 1n49A-5fp2A:
undetectable		 1n49A-5fp2A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 12 SER A 446
TYR A 414
ALA A 138
TYR A 142
GLY A 136
 None
 1.24A 1vpoH-5fp2A:
undetectable
1vpoL-5fp2A:
undetectable		 1vpoH-5fp2A:
16.30
1vpoL-5fp2A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1478_1
(NEURAMINIDASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 7 ASP A 615
SER A 582
SER A 584
GLN A  33
 None
 1.04A 2cmlA-5fp2A:
undetectable		 2cmlA-5fp2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2478_1
(NEURAMINIDASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 8 ASP A 615
SER A 582
SER A 584
GLN A  33
 None
 0.98A 2cmlB-5fp2A:
undetectable		 2cmlB-5fp2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4478_1
(NEURAMINIDASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 8 ASP A 615
SER A 582
SER A 584
GLN A  33
 None
 1.04A 2cmlD-5fp2A:
undetectable		 2cmlD-5fp2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		3 / 3 PRO A 191
THR A 159
PRO A 158
 None
 0.78A 2d55C-5fp2A:
undetectable		 2d55C-5fp2A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		3 / 3 THR A 155
PRO A 124
TYR A 201
 None
 0.97A 2dxrA-5fp2A:
undetectable		 2dxrA-5fp2A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 7 ASN A 533
ASP A 534
GLY A 568
TYR A 530
 None
 0.97A 2f6dA-5fp2A:
undetectable		 2f6dA-5fp2A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 6 SER A 678
GLY A 660
THR A 627
ARG A  48
 None
 0.97A 2f7fA-5fp2A:
undetectable		 2f7fA-5fp2A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 674
ASN A 679
THR A 627
 None
 0.82A 2q63A-5fp2A:
undetectable		 2q63A-5fp2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_0
(CYTOCHROME P450 2R1)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 12 THR A  91
VAL A  95
VAL A 128
ILE A 131
THR A 155
 None
 1.20A 3dl9A-5fp2A:
undetectable		 3dl9A-5fp2A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 5 VAL A 123
ILE A  93
MET A  61
ARG A 157
 None
 1.28A 3pyyB-5fp2A:
undetectable		 3pyyB-5fp2A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 8 ALA A 138
ALA A 464
SER A 446
ALA A 466
ALA A 146
 None
 1.33A 4twdF-5fp2A:
undetectable
4twdG-5fp2A:
undetectable
4twdH-5fp2A:
undetectable
4twdI-5fp2A:
undetectable
4twdJ-5fp2A:
undetectable		 4twdF-5fp2A:
18.46
4twdG-5fp2A:
18.46
4twdH-5fp2A:
18.46
4twdI-5fp2A:
18.46
4twdJ-5fp2A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 143
TYR A 414
SER A 444
ASP A 434
ASN A 373
 None
 1.39A 4ymgB-5fp2A:
undetectable		 4ymgB-5fp2A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  97
TYR A 414
TYR A 142
GLY A 143
 None
 0.93A 5ayfA-5fp2A:
1.8		 5ayfA-5fp2A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		3 / 3 THR A 452
THR A 458
PHE A 519
 None
 0.75A 5cxvA-5fp2A:
undetectable		 5cxvA-5fp2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_A_SAMA401_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 136
GLY A  36
VAL A  64
GLY A 149
GLY A 148
 None
 1.02A 5wyqA-5fp2A:
undetectable		 5wyqA-5fp2A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_A_CP6A704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 10 VAL A 661
ALA A 663
VAL A 677
TYR A 707
THR A 624
 None
 1.08A 6aogA-5fp2A:
undetectable		 6aogA-5fp2A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AOG_B_CP6B704_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 10 VAL A 661
ALA A 663
VAL A 677
TYR A 707
THR A 624
 None
 1.12A 6aogB-5fp2A:
undetectable		 6aogB-5fp2A:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		4 / 6 ASP A 315
ASN A 373
LEU A 350
SER A 351
 None
 1.13A 6ekuA-5fp2A:
undetectable		 6ekuA-5fp2A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 11 SER A 165
VAL A 673
GLY A 664
SER A 623
ALA A 618
 None
 1.39A 6hu9A-5fp2A:
undetectable
6hu9E-5fp2A:
undetectable
6hu9I-5fp2A:
undetectable		 6hu9A-5fp2A:
22.14
6hu9E-5fp2A:
15.68
6hu9I-5fp2A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 5fp2 FERRIC ENTEROBACTIN
RECEPTOR PIRA
(Pseudomonas
aeruginosa) 		5 / 10 SER A 165
VAL A 673
GLY A 664
SER A 623
ALA A 618
 None
 1.42A 6hu9L-5fp2A:
undetectable
6hu9P-5fp2A:
undetectable
6hu9T-5fp2A:
undetectable		 6hu9L-5fp2A:
22.14
6hu9P-5fp2A:
15.68
6hu9T-5fp2A:
7.38