SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5fq2 SUMO-ACTIVATING
ENZYME SUBUNIT 2
(Homo
sapiens) 		4 / 4 LEU B 506
PRO B 478
ILE B 530
LEU B 517
 MLZ  B 505 ( 4.2A)
None
None
None
 1.12A 1ya4B-5fq2B:
undetectable		 1ya4B-5fq2B:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 5fq2 SUMO-ACTIVATING
ENZYME SUBUNIT 2
(Homo
sapiens) 		3 / 3 GLU B 545
ASP B 541
ASP B 537
 None
 0.61A 3jb2A-5fq2B:
undetectable		 3jb2A-5fq2B:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 5fq2 SUMO-ACTIVATING
ENZYME SUBUNIT 2
(Homo
sapiens) 		4 / 8 LEU B 506
VAL B 480
LEU B 490
ILE B 491
 MLZ  B 505 ( 4.2A)
None
None
None
 0.84A 6cb4A-5fq2B:
undetectable		 6cb4A-5fq2B:
15.02