SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fq8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU G 186
LEU G  95
ILE G 133
VAL G 210
ILE G 209
 None
 1.07A 2uxoB-5fq8G:
undetectable		 2uxoB-5fq8G:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		4 / 6 THR G  84
VAL G  85
LEU G  67
GLU G  35
 None
 1.13A 3b6rB-5fq8G:
undetectable		 3b6rB-5fq8G:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_A_FLPA701_1
(CYCLOOXYGENASE-2)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL G 172
TYR G 141
LEU G 137
GLY G 202
ALA G 201
 None
 1.02A 3pghA-5fq8G:
undetectable		 3pghA-5fq8G:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE G  64
TYR G  86
ASP G  22
THR G 101
 None
 1.05A 3q70A-5fq8G:
undetectable		 3q70A-5fq8G:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL G 172
TYR G 141
LEU G 137
GLY G 202
ALA G 201
 None
 1.11A 3rr3C-5fq8G:
undetectable		 3rr3C-5fq8G:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL G 172
TYR G 141
LEU G 137
GLY G 202
ALA G 201
 None
 1.11A 3rr3D-5fq8G:
undetectable		 3rr3D-5fq8G:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR G  69
GLU G  18
TYR G  39
 None
 0.85A 3ug8A-5fq8G:
undetectable		 3ug8A-5fq8G:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		3 / 3 SER G  97
GLY G  98
GLN G 212
 None
 0.58A 3v4tH-5fq8G:
undetectable		 3v4tH-5fq8G:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR G  69
PHE G  33
ARG G  83
 None
 0.90A 4g19D-5fq8G:
undetectable		 4g19D-5fq8G:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		4 / 5 GLY G 138
ASP G 135
GLU G 120
VAL G  26
 None
 1.15A 4nkvD-5fq8G:
undetectable		 4nkvD-5fq8G:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		4 / 5 GLY G 139
ASP G 135
GLU G 120
VAL G  26
 None
 1.10A 4nkvD-5fq8G:
undetectable		 4nkvD-5fq8G:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_A_IBPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL G 172
TYR G 141
LEU G 137
GLY G 202
ALA G 201
 None
 1.05A 4ph9A-5fq8G:
undetectable		 4ph9A-5fq8G:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PH9_B_IBPB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		5 / 10 VAL G 172
TYR G 141
LEU G 137
GLY G 202
ALA G 201
 None
 1.04A 4ph9B-5fq8G:
undetectable		 4ph9B-5fq8G:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		4 / 6 GLU G  35
THR G  80
TYR G  69
PHE G  33
 None
 1.40A 5lrbA-5fq8G:
undetectable		 5lrbA-5fq8G:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		4 / 6 ASN G  73
ALA G  78
VAL G  15
TYR G  72
 None
 1.16A 5umd2-5fq8G:
undetectable
5umdF-5fq8G:
undetectable		 5umd2-5fq8G:
16.43
5umdF-5fq8G:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5fq8 BT_2262
(UNCHARACTERISED
LIPOPROTEIN)
(Bacteroides
thetaiotaomicron) 		3 / 3 TYR G 141
ALA G 201
TYR G 200
 None
 0.86A 5uunB-5fq8G:
undetectable		 5uunB-5fq8G:
22.01