SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fr7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5fr7 AMYR
(Erwinia
amylovora) 		5 / 12 SER A 130
VAL A 103
LEU A  77
ILE A  80
SER A  83
 None
 1.46A 2fj1A-5fr7A:
undetectable		 2fj1A-5fr7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5fr7 AMYR
(Erwinia
amylovora) 		5 / 11 GLY A  44
PHE A  46
ALA A  61
ASP A  43
GLN A  40
 None
 1.25A 3id5B-5fr7A:
undetectable		 3id5B-5fr7A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 5fr7 AMYR
(Erwinia
amylovora) 		5 / 11 GLY A  44
PHE A  46
ALA A  61
ASP A  43
GLN A  40
 None
 1.25A 3id5F-5fr7A:
undetectable		 3id5F-5fr7A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 5fr7 AMYR
(Erwinia
amylovora) 		3 / 3 SER A 130
MET A 134
ASP A  47
 None
 0.94A 4mm4B-5fr7A:
undetectable		 4mm4B-5fr7A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 5fr7 AMYR
(Erwinia
amylovora) 		5 / 11 LEU A  14
ARG A  15
LEU A  36
ASP A  51
LEU A  52
 None
 1.37A 4or0A-5fr7A:
undetectable		 4or0A-5fr7A:
15.41