SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fr8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 6 ILE A  84
ARG A  85
TYR A 143
VAL A  59
 None
 0.75A 1db1A-5fr8A:
undetectable		 1db1A-5fr8A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 GLY A 327
VAL A 329
TRP A 111
SER A 481
LEU A 567
 None
 1.39A 1kiaD-5fr8A:
undetectable		 1kiaD-5fr8A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 8 GLU A  29
ASP A 433
GLU A 415
GLU A 352
 None
 1.07A 1knyA-5fr8A:
undetectable
1knyB-5fr8A:
undetectable		 1knyA-5fr8A:
17.37
1knyB-5fr8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 GLY A 259
ASN A 232
ASN A 122
ARG A 118
VAL A  96
 None
 1.22A 1r30A-5fr8A:
undetectable		 1r30A-5fr8A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 GLY A 259
ASN A 232
ASN A 122
ARG A 118
VAL A  96
 None
 1.22A 1r30B-5fr8A:
undetectable		 1r30B-5fr8A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 4 SER A 131
ILE A 129
VAL A  96
THR A  92
 None
 1.01A 1u70A-5fr8A:
undetectable		 1u70A-5fr8A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.07A 1v55C-5fr8A:
undetectable
1v55J-5fr8A:
undetectable		 1v55C-5fr8A:
16.67
1v55J-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 5 PRO A 469
GLY A 499
ASN A 500
GLY A 501
 None
 1.07A 1zlqA-5fr8A:
undetectable		 1zlqA-5fr8A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.06A 2eijC-5fr8A:
undetectable
2eijJ-5fr8A:
undetectable		 2eijC-5fr8A:
16.67
2eijJ-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.05A 2einC-5fr8A:
undetectable
2einJ-5fr8A:
undetectable		 2einC-5fr8A:
16.67
2einJ-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 ASP A 433
PHE A 432
TYR A 413
THR A 369
 None
 1.40A 2q6kA-5fr8A:
undetectable		 2q6kA-5fr8A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 ASN A  78
ARG A 227
ASP A 176
 None
 0.84A 2qe6A-5fr8A:
undetectable		 2qe6A-5fr8A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 ASN A  78
ARG A 227
ASP A 176
 None
 0.91A 2qe6B-5fr8A:
undetectable		 2qe6B-5fr8A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1353_1
(PROSTAGLANDIN
REDUCTASE 2)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 9 THR A 346
PHE A 376
GLU A 373
VAL A 372
MET A 471
 None
 1.37A 2w98A-5fr8A:
undetectable		 2w98A-5fr8A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 TYR A 715
GLU A 717
THR A 639
 None
 0.92A 2y7hB-5fr8A:
undetectable		 2y7hB-5fr8A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 5 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.15A 3ablC-5fr8A:
undetectable
3ablJ-5fr8A:
undetectable		 3ablC-5fr8A:
16.67
3ablJ-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 6 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.18A 3ablP-5fr8A:
undetectable
3ablW-5fr8A:
undetectable		 3ablP-5fr8A:
16.67
3ablW-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 THR A  68
GLY A  88
GLY A  74
ASN A  66
LEU A 612
 None
 1.19A 3eeyH-5fr8A:
undetectable		 3eeyH-5fr8A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 8 ARG A 104
SER A 106
ASP A 374
LEU A  93
 None
 1.17A 3jq7B-5fr8A:
undetectable		 3jq7B-5fr8A:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 LEU A 576
GLY A 579
ILE A 617
PRO A 611
ILE A 577
 None
 0.90A 3k4vD-5fr8A:
undetectable		 3k4vD-5fr8A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 GLY A 385
TRP A 564
VAL A 547
 None
 0.77A 3n65B-5fr8A:
undetectable		 3n65B-5fr8A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 LEU A 576
GLY A 579
ILE A 617
PRO A 611
ILE A 577
 None
 0.95A 3nduD-5fr8A:
undetectable		 3nduD-5fr8A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 PRO A 616
TYR A 618
THR A 619
ILE A 620
 None
 0.82A 3p50A-5fr8A:
undetectable		 3p50A-5fr8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 PRO A 616
TYR A 618
THR A 619
ILE A 620
 None
 0.82A 3p50B-5fr8A:
undetectable		 3p50B-5fr8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_C_PFLC319_1
(GLR4197 PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 PRO A 616
TYR A 618
THR A 619
ILE A 620
 None
 0.84A 3p50C-5fr8A:
undetectable		 3p50C-5fr8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_D_PFLD320_1
(GLR4197 PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 PRO A 616
TYR A 618
THR A 619
ILE A 620
 None
 0.82A 3p50D-5fr8A:
undetectable		 3p50D-5fr8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 7 PRO A 616
TYR A 618
THR A 619
ILE A 620
 None
 0.85A 3p50E-5fr8A:
undetectable		 3p50E-5fr8A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 8 GLY A 719
ILE A 216
SER A 219
ASP A 701
 None
 0.77A 3pwwA-5fr8A:
undetectable		 3pwwA-5fr8A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 THR A  42
VAL A  40
GLU A 130
 None
 0.68A 3v4tA-5fr8A:
undetectable
3v4tD-5fr8A:
undetectable		 3v4tA-5fr8A:
21.20
3v4tD-5fr8A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 8 ARG A 136
ARG A  85
GLU A 581
LYS A 459
 None
 1.19A 4bqfB-5fr8A:
undetectable		 4bqfB-5fr8A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 TYR A 478
ARG A 108
SER A 381
 None
 1.12A 4dr2I-5fr8A:
undetectable
4dr2J-5fr8A:
undetectable		 4dr2I-5fr8A:
11.60
4dr2J-5fr8A:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 5 ASN A 217
ALA A 224
GLY A 226
ASP A  83
 None
 0.89A 4n48A-5fr8A:
undetectable		 4n48A-5fr8A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 GLU A 323
ASP A 116
LEU A 281
LEU A 278
GLY A 264
 None
 1.44A 4pfjB-5fr8A:
undetectable		 4pfjB-5fr8A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 GLU A 323
ASP A 116
LEU A 281
LEU A 278
GLY A 264
 None
 1.47A 4pgfB-5fr8A:
undetectable		 4pgfB-5fr8A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 THR A 714
GLY A  77
ASN A  79
GLN A  75
SER A 670
 None
 1.38A 4pooB-5fr8A:
undetectable		 4pooB-5fr8A:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 ARG A 108
GLU A  90
TYR A 472
 None
 1.00A 4r29D-5fr8A:
undetectable		 4r29D-5fr8A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 THR A 639
ASN A 621
SER A 622
 None
None
C8E  A1731 (-3.2A)
 0.68A 4tvtA-5fr8A:
undetectable		 4tvtA-5fr8A:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 9 ALA A 463
SER A 445
ALA A 465
ALA A 147
ALA A 139
 None
 1.26A 4twdA-5fr8A:
undetectable
4twdB-5fr8A:
undetectable
4twdC-5fr8A:
undetectable
4twdD-5fr8A:
undetectable
4twdE-5fr8A:
undetectable		 4twdA-5fr8A:
20.06
4twdB-5fr8A:
20.06
4twdC-5fr8A:
20.06
4twdD-5fr8A:
20.06
4twdE-5fr8A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 8 ALA A 139
ALA A 463
SER A 445
ALA A 465
ALA A 147
 None
 1.19A 4twdF-5fr8A:
undetectable
4twdG-5fr8A:
undetectable
4twdH-5fr8A:
undetectable
4twdI-5fr8A:
undetectable
4twdJ-5fr8A:
undetectable		 4twdF-5fr8A:
20.06
4twdG-5fr8A:
20.06
4twdH-5fr8A:
20.06
4twdI-5fr8A:
20.06
4twdJ-5fr8A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 MET A  62
GLN A 640
TYR A 618
 None
 1.06A 4udcA-5fr8A:
undetectable		 4udcA-5fr8A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 ILE A 577
GLY A 150
PHE A 529
THR A 598
THR A  92
 None
 1.09A 5byjA-5fr8A:
undetectable		 5byjA-5fr8A:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 TYR A 206
LYS A 231
LYS A 208
 None
 1.13A 5dbyA-5fr8A:
undetectable		 5dbyA-5fr8A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 ILE A 129
VAL A  40
VAL A 134
SER A 131
VAL A  96
 None
 1.16A 5n0oA-5fr8A:
undetectable		 5n0oA-5fr8A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 ILE A 129
VAL A  40
VAL A 134
SER A 131
VAL A  96
 None
 1.16A 5n0sB-5fr8A:
undetectable		 5n0sB-5fr8A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 5 VAL A 672
PRO A 616
GLY A 642
TYR A 641
 None
 1.37A 5x80A-5fr8A:
undetectable
5x80B-5fr8A:
undetectable		 5x80A-5fr8A:
11.48
5x80B-5fr8A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 5 PRO A 616
GLY A 642
TYR A 641
VAL A 672
 None
 1.41A 5x80C-5fr8A:
undetectable
5x80D-5fr8A:
undetectable		 5x80C-5fr8A:
11.48
5x80D-5fr8A:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 6 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.12A 5z84P-5fr8A:
undetectable
5z84W-5fr8A:
undetectable		 5z84P-5fr8A:
16.67
5z84W-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 6 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.06A 5z86C-5fr8A:
undetectable
5z86J-5fr8A:
undetectable		 5z86C-5fr8A:
16.67
5z86J-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 6 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.08A 5z86P-5fr8A:
undetectable
5z86W-5fr8A:
undetectable		 5z86P-5fr8A:
16.67
5z86W-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 6 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.11A 5zcpC-5fr8A:
undetectable
5zcpJ-5fr8A:
undetectable		 5zcpC-5fr8A:
16.67
5zcpJ-5fr8A:
5.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 9 ALA A 463
ALA A 139
GLY A 137
SER A  35
GLY A  37
 None
 1.11A 6bklE-5fr8A:
undetectable
6bklF-5fr8A:
undetectable
6bklG-5fr8A:
undetectable
6bklH-5fr8A:
undetectable		 6bklE-5fr8A:
3.34
6bklF-5fr8A:
3.34
6bklG-5fr8A:
3.34
6bklH-5fr8A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 5 GLY A 501
ASN A 500
ASP A 502
ARG A 568
 None
 1.37A 6dwdB-5fr8A:
undetectable
6dwdD-5fr8A:
undetectable		 6dwdB-5fr8A:
21.95
6dwdD-5fr8A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 ASN A  66
ILE A  82
VAL A 152
ILE A  94
PRO A 138
 None
 1.16A 6hlpA-5fr8A:
undetectable		 6hlpA-5fr8A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		5 / 12 LEU A 479
THR A 546
ILE A 566
TYR A 393
ALA A 326
 None
 1.30A 6ie8A-5fr8A:
undetectable		 6ie8A-5fr8A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		3 / 3 ASP A  97
SER A 293
SER A 254
 None
 0.79A 6mxtA-5fr8A:
undetectable		 6mxtA-5fr8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fr8 TONB-DEPENDENT
SIDEROPHORE RECEPTOR
(Acinetobacter
baumannii) 		4 / 6 GLN A 518
PHE A 517
LEU A 586
PHE A 588
 None
 1.14A 6nmpC-5fr8A:
undetectable
6nmpJ-5fr8A:
undetectable		 6nmpC-5fr8A:
16.67
6nmpJ-5fr8A:
5.52