SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5frs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 7 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.86A 11gsA-5frsA:
undetectable
11gsA-5frsA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 VAL A 185
ILE A 193
VAL A 219
ILE A 171
LEU A 149
None
1.17A 1fm4A-5frsA:
undetectable
1fm4A-5frsA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 ILE A 281
ALA A 279
LEU A 269
LEU A 302
ILE A 284
None
1.01A 1ra2A-5frsA:
undetectable
1ra2A-5frsA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 ILE A 281
ALA A 279
LEU A 269
LEU A 302
ILE A 284
None
0.98A 1rb2A-5frsA:
undetectable
1rb2A-5frsA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 ILE A 281
ALA A 279
LEU A 269
LEU A 302
ILE A 284
None
1.01A 1rd7A-5frsA:
undetectable
1rd7A-5frsA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 PHE A 197
TYR A 217
LEU A 221
ASP A 225
None
0.89A 1rmtC-5frsA:
undetectable
1rmtC-5frsA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 PHE A 197
TYR A 217
LEU A 221
ASP A 225
None
0.87A 1rmtD-5frsA:
undetectable
1rmtD-5frsA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 ILE A 281
ALA A 279
LEU A 269
LEU A 302
ILE A 284
None
1.01A 1rx7A-5frsA:
undetectable
1rx7A-5frsA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 5 ILE A 523
SER A 641
LEU A 583
ASN A 584
None
1.15A 1y0xX-5frsA:
undetectable
1y0xX-5frsA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 4 LEU A  98
LEU A  80
SER A  81
LEU A 130
None
1.16A 1ya3A-5frsA:
undetectable
1ya3A-5frsA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 4 ILE A 306
ASP A 321
LEU A 288
ARG A 352
None
1.21A 2a7qA-5frsA:
undetectable
2a7qA-5frsA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.86A 2gssA-5frsA:
undetectable
2gssA-5frsA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.86A 2gssB-5frsA:
undetectable
2gssB-5frsA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 10 SER A 344
ILE A 348
ILE A 349
LEU A 359
ILE A 330
None
1.21A 2nnhB-5frsA:
undetectable
2nnhB-5frsA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 6 ASP A 214
TYR A 217
PHE A 156
LEU A 175
None
1.10A 2w98A-5frsA:
undetectable
2w98B-5frsA:
undetectable
2w98A-5frsA:
18.70
2w98B-5frsA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
6 / 12 ILE A 394
SER A 402
PHE A 367
LEU A 363
ALA A 364
VAL A 385
None
1.39A 3dzyA-5frsA:
undetectable
3dzyA-5frsA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 7 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.86A 3gssA-5frsA:
undetectable
3gssA-5frsA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 7 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.86A 3gssB-5frsA:
undetectable
3gssB-5frsA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.90A 3hjoA-5frsA:
2.2
3hjoA-5frsA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 ASP A 214
LEU A 112
PHE A 109
ILE A 127
LEU A 167
None
1.28A 3ko0G-5frsA:
undetectable
3ko0H-5frsA:
undetectable
3ko0I-5frsA:
undetectable
3ko0J-5frsA:
undetectable
3ko0G-5frsA:
8.68
3ko0H-5frsA:
8.68
3ko0I-5frsA:
8.68
3ko0J-5frsA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 LEU A 112
PHE A 109
ILE A 127
LEU A 167
ASP A 214
None
1.20A 3ko0K-5frsA:
undetectable
3ko0L-5frsA:
undetectable
3ko0S-5frsA:
undetectable
3ko0T-5frsA:
undetectable
3ko0K-5frsA:
8.68
3ko0L-5frsA:
8.68
3ko0S-5frsA:
8.68
3ko0T-5frsA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 LEU A 112
PHE A 109
ILE A 127
LEU A 167
ASP A 214
None
1.20A 3ko0M-5frsA:
undetectable
3ko0N-5frsA:
undetectable
3ko0O-5frsA:
undetectable
3ko0P-5frsA:
undetectable
3ko0M-5frsA:
8.68
3ko0N-5frsA:
8.68
3ko0O-5frsA:
8.68
3ko0P-5frsA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 TYR A 157
VAL A 219
ILE A 179
GLY A 172
None
0.91A 3n9jA-5frsA:
undetectable
3n9jA-5frsA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 6 TYR A 454
PHE A 497
PRO A 450
LEU A 494
None
1.22A 3tgvD-5frsA:
undetectable
3tgvD-5frsA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
3 / 3 ASP A  53
LYS A  54
ASP A  57
None
0.80A 4a7tA-5frsA:
undetectable
4a7tA-5frsA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 VAL A 185
ILE A 193
VAL A 219
ILE A 171
LEU A 149
None
1.10A 4a84A-5frsA:
undetectable
4a84A-5frsA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 9 TYR A 157
LEU A 223
LEU A 175
GLY A 176
VAL A 185
None
1.43A 4c9kA-5frsA:
undetectable
4c9kA-5frsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 9 TYR A 157
LEU A 223
LEU A 175
GLY A 176
VAL A 185
None
1.42A 4c9kB-5frsA:
undetectable
4c9kB-5frsA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 5 LEU A  39
ILE A  15
ALA A  34
PHE A  11
None
0.89A 4dc3B-5frsA:
undetectable
4dc3B-5frsA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 ILE A 281
ALA A 279
LEU A 269
LEU A 302
ILE A 284
None
0.92A 4ej1A-5frsA:
undetectable
4ej1A-5frsA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 LEU A 126
SER A 135
LEU A 138
PHE A 102
ALA A  77
None
1.39A 4hwkC-5frsA:
undetectable
4hwkC-5frsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 11 LEU A 126
SER A 135
LEU A 138
PHE A 102
ALA A  77
None
1.36A 4hwkD-5frsA:
undetectable
4hwkD-5frsA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 ILE A 281
ALA A 279
LEU A 269
LEU A 302
ILE A 284
None
0.90A 4i13A-5frsA:
undetectable
4i13A-5frsA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 SER A 135
SER A  81
ALA A  88
LEU A  86
None
0.93A 4iklA-5frsA:
undetectable
4iklB-5frsA:
undetectable
4iklA-5frsA:
12.75
4iklB-5frsA:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_E_IPHE101_0
(INSULIN)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 11 ILE A 277
LEU A 235
HIS A 263
LEU A 265
LEU A 302
None
1.07A 4p65E-5frsA:
undetectable
4p65F-5frsA:
undetectable
4p65J-5frsA:
undetectable
4p65L-5frsA:
undetectable
4p65E-5frsA:
3.21
4p65F-5frsA:
5.45
4p65J-5frsA:
5.45
4p65L-5frsA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 ILE A 136
PHE A 109
PHE A 163
GLY A 172
None
0.98A 4qogA-5frsA:
undetectable
4qogB-5frsA:
undetectable
4qogA-5frsA:
14.73
4qogB-5frsA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
4 / 8 THR A 366
LEU A 363
ILE A 345
LEU A 359
None
0.86A 5g48A-5frsA:
undetectable
5g48A-5frsA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 10 VAL A 170
ILE A 174
LEU A 152
PHE A 156
ILE A 121
None
1.29A 5hw8C-5frsA:
undetectable
5hw8H-5frsA:
undetectable
5hw8C-5frsA:
10.30
5hw8H-5frsA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
3 / 3 LYS A 668
ASP A 666
ILE A 675
None
0.87A 5kc4E-5frsA:
undetectable
5kc4E-5frsA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
3 / 3 HIS A  36
LYS A  33
PHE A  75
None
1.46A 5klaA-5frsA:
3.1
5klaA-5frsA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 LEU A 131
VAL A 170
GLY A 172
PHE A 109
PHE A 156
None
1.11A 6a94A-5frsA:
2.2
6a94A-5frsA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
5 / 12 LEU A 131
VAL A 170
GLY A 172
PHE A 109
VAL A 105
None
0.79A 6a94A-5frsA:
2.2
6a94A-5frsA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae)
6 / 12 LEU A 131
VAL A 170
GLY A 172
PHE A 109
PHE A 156
VAL A 105
None
1.08A 6a94B-5frsA:
undetectable
6a94B-5frsA:
20.37