SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5frt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5frt DIMERIC (2FE-2S)
PROTEIN
(Azotobacter
vinelandii) 		4 / 8 PHE A   6
VAL A 106
THR A 104
VAL A  52
 None
 1.15A 1uyuB-5frtA:
undetectable		 1uyuB-5frtA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1003_0
(ALDEHYDE
DEHYDROGENASE A)		 5frt DIMERIC (2FE-2S)
PROTEIN
(Azotobacter
vinelandii) 		4 / 5 ILE A   4
LEU A 111
ASP A 108
ALA A  19
 None
 0.95A 2opxA-5frtA:
undetectable		 2opxA-5frtA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 5frt DIMERIC (2FE-2S)
PROTEIN
(Azotobacter
vinelandii) 		5 / 11 ALA A 101
THR A 104
ILE A  54
ILE A  38
ALA A  31
 None
 1.02A 2qhfA-5frtA:
undetectable		 2qhfA-5frtA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5frt DIMERIC (2FE-2S)
PROTEIN
(Azotobacter
vinelandii) 		5 / 10 VAL A 113
PHE A 115
SER A  49
GLY A  29
ALA A  31
 None
None
FES  A5000 ( 3.9A)
None
None
 1.48A 2x2iB-5frtA:
undetectable		 2x2iB-5frtA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5frt DIMERIC (2FE-2S)
PROTEIN
(Azotobacter
vinelandii) 		5 / 11 PHE A 115
GLY A 117
GLY A  29
GLU A  33
ASN A  34
 None
 1.33A 4a6nA-5frtA:
undetectable		 4a6nA-5frtA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5frt DIMERIC (2FE-2S)
PROTEIN
(Azotobacter
vinelandii) 		4 / 5 VAL A  30
VAL A  36
GLY A  35
PHE A   6
 None
 1.08A 5d4nA-5frtA:
undetectable
5d4nC-5frtA:
undetectable		 5d4nA-5frtA:
24.06
5d4nC-5frtA:
24.06