SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ft1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ft1 GP37
(Pseudomonas
virus
phiKZ) 		4 / 5 SER A  76
ARG A  77
PRO A 132
GLY A 133
 None
 0.76A 2y7kB-5ft1A:
undetectable		 2y7kB-5ft1A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5ft1 GP37
(Pseudomonas
virus
phiKZ) 		4 / 6 SER A  76
ARG A  77
PRO A 132
GLY A 133
 None
 0.79A 2y7pA-5ft1A:
undetectable		 2y7pA-5ft1A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5ft1 GP37
(Pseudomonas
virus
phiKZ) 		3 / 3 SER A 212
GLU A 222
ASP A 137
 None
 0.84A 3bwmA-5ft1A:
undetectable		 3bwmA-5ft1A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 5ft1 GP37
(Pseudomonas
virus
phiKZ) 		4 / 5 LEU A  18
LEU A  15
LEU A  75
SER A  76
 None
 0.95A 3vhuA-5ft1A:
undetectable		 3vhuA-5ft1A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5ft1 GP37
(Pseudomonas
virus
phiKZ) 		3 / 3 SER A 212
GLU A 222
ASP A 137
 None
 0.84A 4xudA-5ft1A:
undetectable		 4xudA-5ft1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_A_ACTA403_0
(3C-LIKE PROTEINASE)		 5ft1 GP37
(Pseudomonas
virus
phiKZ) 		4 / 5 TYR A 210
SER A 147
LEU A 143
GLN A 150
 None
 1.40A 4yo9A-5ft1A:
undetectable
4yo9B-5ft1A:
undetectable		 4yo9A-5ft1A:
23.15
4yo9B-5ft1A:
23.15