SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fta'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q5S_A_ACHA1289_0 (MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR)	5fta	BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3 (Homo sapiens)	4 / 6	VAL A 38 TYR A 43 GLU A 111 ILE A 87	None	1.11A	3q5sA-5ftaA: undetectable	3q5sA-5ftaA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UG8_A_IMNA2001_2 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3)	5fta	BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3 (Homo sapiens)	3 / 3	TYR A 90 GLU A 111 TYR A 114	None	0.98A	3ug8A-5ftaA: undetectable	3ug8A-5ftaA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ACTA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5fta	BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN 3 (Homo sapiens)	4 / 6	PHE A 84 VAL A 38 MET A 60 ILE A 75	None	1.00A	5iwuA-5ftaA: undetectable	5iwuA-5ftaA: 16.39