SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ftz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
5 / 11 SER A 172
VAL A 199
PHE A 201
LEU A 174
PHE A 150
None
1.18A 1uduA-5ftzA:
undetectable
1uduA-5ftzA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 1v54N-5ftzA:
undetectable
1v54P-5ftzA:
undetectable
1v54N-5ftzA:
16.94
1v54P-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 5 SER A 143
TYR A 128
SER A  79
ASP A  74
None
1.40A 1vidA-5ftzA:
undetectable
1vidA-5ftzA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 SER A 143
TYR A 128
SER A  79
ASP A  74
None
1.37A 2cl5B-5ftzA:
undetectable
2cl5B-5ftzA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 2eikA-5ftzA:
undetectable
2eikC-5ftzA:
undetectable
2eikA-5ftzA:
16.94
2eikC-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.34A 2eimA-5ftzA:
undetectable
2eimC-5ftzA:
undetectable
2eimA-5ftzA:
16.94
2eimC-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.37A 2eimN-5ftzA:
undetectable
2eimP-5ftzA:
undetectable
2eimN-5ftzA:
16.94
2eimP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.35A 2einA-5ftzA:
undetectable
2einC-5ftzA:
undetectable
2einA-5ftzA:
16.94
2einC-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.39A 2einN-5ftzA:
undetectable
2einP-5ftzA:
undetectable
2einN-5ftzA:
16.94
2einP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 8 SER A 197
TYR A 110
ASP A  34
ARG A 113
None
0.91A 2v57A-5ftzA:
undetectable
2v57A-5ftzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 8 SER A 197
TYR A 110
ASP A  34
ARG A 113
None
0.91A 2v57C-5ftzA:
undetectable
2v57C-5ftzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 SER A 143
TYR A 128
SER A  79
ASP A  74
None
1.39A 2zvjA-5ftzA:
undetectable
2zvjA-5ftzA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.35A 3abmN-5ftzA:
undetectable
3abmP-5ftzA:
undetectable
3abmN-5ftzA:
16.94
3abmP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 3ag1A-5ftzA:
undetectable
3ag1C-5ftzA:
undetectable
3ag1A-5ftzA:
16.94
3ag1C-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.36A 3ag4N-5ftzA:
undetectable
3ag4P-5ftzA:
undetectable
3ag4N-5ftzA:
16.94
3ag4P-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 3asnA-5ftzA:
undetectable
3asnC-5ftzA:
undetectable
3asnA-5ftzA:
16.94
3asnC-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
3 / 3 ARG A 113
VAL A 104
THR A 102
None
0.76A 3cyxA-5ftzA:
undetectable
3cyxA-5ftzA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
5 / 12 VAL A 183
ALA A 182
GLY A  71
ASP A 124
THR A 185
None
1.18A 4mm8A-5ftzA:
undetectable
4mm8A-5ftzA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 5 ILE A  77
PHE A 112
SER A  79
ASP A 198
None
1.44A 4rzvB-5ftzA:
undetectable
4rzvB-5ftzA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 5b1aN-5ftzA:
undetectable
5b1aP-5ftzA:
undetectable
5b1aN-5ftzA:
16.94
5b1aP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 5b3sN-5ftzA:
undetectable
5b3sP-5ftzA:
undetectable
5b3sN-5ftzA:
16.94
5b3sP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 5 SER A 143
TYR A 128
SER A  79
ASP A  74
None
1.38A 5fhrA-5ftzA:
undetectable
5fhrA-5ftzA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 5iy5A-5ftzA:
undetectable
5iy5C-5ftzA:
undetectable
5iy5A-5ftzA:
16.94
5iy5C-5ftzA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
3 / 3 ARG A 142
PRO A  72
TYR A 128
None
0.94A 5tzoB-5ftzA:
undetectable
5tzoB-5ftzA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.34A 5x19N-5ftzA:
undetectable
5x19P-5ftzA:
undetectable
5x19N-5ftzA:
16.94
5x19P-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.33A 5x1bN-5ftzA:
undetectable
5x1bP-5ftzA:
undetectable
5x1bN-5ftzA:
16.94
5x1bP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.36A 5x1fN-5ftzA:
undetectable
5x1fP-5ftzA:
undetectable
5x1fN-5ftzA:
16.94
5x1fP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 7 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.32A 5zcqN-5ftzA:
undetectable
5zcqP-5ftzA:
undetectable
5zcqN-5ftzA:
16.94
5zcqP-5ftzA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 5 GLN A  40
THR A  33
THR A 185
LEU A 181
None
1.30A 6aphA-5ftzA:
undetectable
6aphA-5ftzA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 4 GLN A  40
THR A  33
THR A 185
LEU A 181
None
1.29A 6f3mA-5ftzA:
undetectable
6f3mA-5ftzA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 4 GLN A  40
THR A  33
THR A 185
LEU A 181
None
1.27A 6f3mC-5ftzA:
undetectable
6f3mC-5ftzA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 5 GLN A  40
THR A  33
THR A 185
LEU A 181
None
1.35A 6gbnB-5ftzA:
undetectable
6gbnB-5ftzA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5ftz CHITIN BINDING
PROTEIN

(Streptomyces
lividans)
4 / 6 HIS A 120
ASP A 124
TYR A 155
HIS A  30
CU  A 202 (-3.1A)
None
None
CU  A 202 (-2.9A)
1.30A 6nmpA-5ftzA:
undetectable
6nmpC-5ftzA:
undetectable
6nmpA-5ftzA:
16.94
6nmpC-5ftzA:
22.39