SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fu6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 8 TYR C 744
ILE C 715
GLU C 720
ARG C 708
 None
 0.90A 1mrjA-5fu6C:
undetectable		 1mrjA-5fu6C:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 6 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.94A 2zxwP-5fu6C:
undetectable
2zxwW-5fu6C:
undetectable		 2zxwP-5fu6C:
18.59
2zxwW-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 6 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.93A 3abkP-5fu6C:
undetectable
3abkW-5fu6C:
undetectable		 3abkP-5fu6C:
18.59
3abkW-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 6 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.97A 3ag1C-5fu6C:
undetectable
3ag1J-5fu6C:
undetectable		 3ag1C-5fu6C:
18.59
3ag1J-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		3 / 3 ARG C 665
PRO C 655
PHE C 662
 None
 1.01A 3thrC-5fu6C:
undetectable		 3thrC-5fu6C:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 6 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.98A 3wg7P-5fu6C:
undetectable
3wg7W-5fu6C:
undetectable		 3wg7P-5fu6C:
18.59
3wg7W-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		5 / 11 ILE C 715
GLU C 718
GLY C 739
TYR C 724
GLU C 711
 None
 1.45A 4j83A-5fu6C:
undetectable		 4j83A-5fu6C:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.99A 5iy5P-5fu6C:
undetectable
5iy5W-5fu6C:
undetectable		 5iy5P-5fu6C:
19.10
5iy5W-5fu6C:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 6 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.93A 5w97C-5fu6C:
undetectable
5w97J-5fu6C:
undetectable		 5w97C-5fu6C:
18.59
5w97J-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.98A 5x1fC-5fu6C:
undetectable
5x1fJ-5fu6C:
undetectable		 5x1fC-5fu6C:
18.59
5x1fJ-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 1.00A 5xdxC-5fu6C:
undetectable
5xdxJ-5fu6C:
undetectable		 5xdxC-5fu6C:
19.03
5xdxJ-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 5 LEU C 671
PHE C 673
LEU C 666
PHE C 662
 None
 0.98A 5xdxP-5fu6C:
undetectable
5xdxW-5fu6C:
undetectable		 5xdxP-5fu6C:
19.03
5xdxW-5fu6C:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 5fu6 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 3
(Homo
sapiens) 		4 / 6 TYR C 744
ILE C 715
GLU C 720
ARG C 708
 None
 0.96A 5z3jA-5fu6C:
undetectable		 5z3jA-5fu6C:
18.49