SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fu7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 LEU A2218
LEU A2214
LEU A2184
THR A2224
PHE A2168
 None
 1.28A 1a28A-5fu7A:
undetectable		 1a28A-5fu7A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 10 LEU A2289
ALA A2161
TYR A2283
LEU A2274
HIS A2231
 None
 1.44A 1aqbA-5fu7A:
undetectable		 1aqbA-5fu7A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
NANOS, ISOFORM B
(Homo
sapiens;
Drosophila
melanogaster) 		5 / 9 ALA D 124
ILE A1895
GLY A1951
THR A1958
SER D 126
 None
 1.15A 1c9sQ-5fu7D:
undetectable
1c9sR-5fu7D:
undetectable		 1c9sQ-5fu7D:
18.42
1c9sR-5fu7D:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 5 PHE A1985
LEU A2026
VAL A1907
ASP A1977
 None
 1.38A 1dz6A-5fu7A:
undetectable		 1dz6A-5fu7A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens;
Homo
sapiens) 		5 / 12 PHE B 355
GLY B 356
GLU A2261
ARG A2209
LEU A2265
 None
 1.22A 1mj2A-5fu7B:
undetectable
1mj2B-5fu7B:
undetectable		 1mj2A-5fu7B:
17.75
1mj2B-5fu7B:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens;
Homo
sapiens) 		5 / 12 PHE B 355
GLY B 356
GLU A2261
ARG A2209
LEU A2265
 None
 1.18A 1mj2C-5fu7B:
undetectable
1mj2D-5fu7B:
undetectable		 1mj2C-5fu7B:
17.75
1mj2D-5fu7B:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens;
Homo
sapiens) 		5 / 12 PHE B 355
GLY B 356
GLU A2261
ARG A2209
LEU A2265
 None
 1.25A 1mjoC-5fu7B:
undetectable
1mjoD-5fu7B:
undetectable		 1mjoC-5fu7B:
17.75
1mjoD-5fu7B:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 6 ASN A2216
ASN A2272
ARG A2311
ILE A2121
 None
 1.02A 1oniA-5fu7A:
0.4
1oniB-5fu7A:
undetectable		 1oniA-5fu7A:
14.64
1oniB-5fu7A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 6 ASN A2216
ASN A2272
ARG A2311
ILE A2121
 None
 1.06A 1oniD-5fu7A:
undetectable
1oniF-5fu7A:
undetectable		 1oniD-5fu7A:
14.64
1oniF-5fu7A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
NANOS, ISOFORM B
(Homo
sapiens;
Drosophila
melanogaster) 		5 / 10 ALA D 124
ILE A1895
GLY A1951
THR A1958
SER D 126
 None
 1.15A 1utdE-5fu7D:
undetectable
1utdF-5fu7D:
undetectable		 1utdE-5fu7D:
18.42
1utdF-5fu7D:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
NANOS, ISOFORM B
(Homo
sapiens;
Drosophila
melanogaster) 		5 / 10 ALA D 124
ILE A1895
GLY A1951
THR A1958
SER D 126
 None
 1.14A 1utdH-5fu7D:
undetectable
1utdI-5fu7D:
undetectable		 1utdH-5fu7D:
18.42
1utdI-5fu7D:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 6 LEU A1975
GLN A1976
LEU A2026
PHE A2034
 None
 1.11A 2einP-5fu7A:
2.8
2einW-5fu7A:
undetectable		 2einP-5fu7A:
18.30
2einW-5fu7A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 6 LEU A2258
ASN A2204
GLN A2213
ILE A2215
 None
 1.22A 2jn3A-5fu7A:
undetectable		 2jn3A-5fu7A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 8 ILE A2242
PHE A2251
PHE A2284
GLY A2223
 None
 0.67A 2vdbA-5fu7A:
undetectable		 2vdbA-5fu7A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 9 ILE A1993
ARG A1992
ALA A1938
VAL A1940
 None
 0.95A 2vufB-5fu7A:
1.8		 2vufB-5fu7A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 5 GLN A2252
PHE A2251
LEU A2196
PHE A2192
 None
 1.06A 3ablC-5fu7A:
2.8
3ablJ-5fu7A:
undetectable		 3ablC-5fu7A:
18.30
3ablJ-5fu7A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 6 LEU A1975
GLN A1976
LEU A2026
PHE A2034
 None
 1.01A 3ag1C-5fu7A:
2.8
3ag1J-5fu7A:
undetectable		 3ag1C-5fu7A:
18.30
3ag1J-5fu7A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		3 / 3 CYH A2020
PHE A2019
PHE A2023
 None
 1.05A 3cr5X-5fu7A:
0.9		 3cr5X-5fu7A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens;
Homo
sapiens) 		4 / 6 ILE A2046
THR A2055
PHE A2106
TYR B 396
 None
 1.33A 3elzB-5fu7A:
undetectable		 3elzB-5fu7A:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens) 		5 / 11 LEU A2309
LEU B 360
GLU A2310
ASN A2130
LEU B 378
 None
 1.38A 3ndvA-5fu7A:
undetectable
3ndvB-5fu7A:
undetectable		 3ndvA-5fu7A:
21.96
3ndvB-5fu7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens) 		3 / 3 TYR B 518
GLU B 522
TYR B 471
 None
 0.84A 3ug8A-5fu7B:
undetectable		 3ug8A-5fu7B:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens;
Homo
sapiens) 		4 / 6 ARG A2197
ASP B 353
GLU A2298
LEU A2258
 None
 1.24A 4ax8A-5fu7A:
undetectable		 4ax8A-5fu7A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 11 LEU A2309
LEU A2312
ILE A2313
ARG A2316
ILE A2330
 None
 1.11A 4dm8A-5fu7A:
undetectable		 4dm8A-5fu7A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		3 / 3 TYR A2276
HIS A2114
ARG A2275
 None
 0.86A 4htfA-5fu7A:
undetectable		 4htfA-5fu7A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens) 		4 / 5 LEU B 360
GLY B 359
ILE A2349
LYS A2351
 None
 1.20A 4ma8C-5fu7B:
undetectable		 4ma8C-5fu7B:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 6 ASN A2130
MET A2288
LEU A2308
VAL A2356
 None
 1.17A 4okbA-5fu7A:
undetectable		 4okbA-5fu7A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 LEU A1967
ASN A1964
GLY A1968
LEU A2026
ILE A1960
 None
 1.35A 4p6xE-5fu7A:
undetectable		 4p6xE-5fu7A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 PHE A2023
CYH A2020
PHE A2047
MET A2051
LEU A1967
 None
 1.19A 4xldA-5fu7A:
undetectable		 4xldA-5fu7A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 11 MET A2088
LEU A2091
LEU A2128
LEU A2096
LEU A2079
 None
 1.30A 4zn7B-5fu7A:
2.8		 4zn7B-5fu7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 2
(Homo
sapiens) 		3 / 3 ARG B 481
TYR B 518
GLU B 495
 None
 0.52A 4zzbE-5fu7B:
undetectable		 4zzbE-5fu7B:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 TYR A2221
PHE A2251
ILE A2250
PHE A2284
PHE A2168
 None
 1.20A 5fsaA-5fu7A:
undetectable		 5fsaA-5fu7A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 LEU A2212
ASP A2259
GLY A2262
ALA A2269
ASN A2216
 None
 1.22A 5kc4A-5fu7A:
0.8		 5kc4A-5fu7A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 LEU A2212
ASP A2259
GLY A2262
ALA A2269
ASN A2216
 None
 1.26A 5kc4E-5fu7A:
undetectable		 5kc4E-5fu7A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 8 ASN A2272
ALA A2271
GLN A2273
HIS A2114
 None
 1.05A 5km8A-5fu7A:
undetectable
5km8B-5fu7A:
undetectable		 5km8A-5fu7A:
15.52
5km8B-5fu7A:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 TYR A2221
PHE A2251
ILE A2250
PHE A2284
PHE A2168
 None
 1.19A 5v5zA-5fu7A:
undetectable		 5v5zA-5fu7A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 12 PHE A2023
CYH A2020
PHE A2047
MET A2051
LEU A1967
 None
 1.09A 5y2oA-5fu7A:
undetectable		 5y2oA-5fu7A:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 8 HIS A2024
PHE A2023
PHE A2047
MET A2051
 None
 1.11A 5y2tB-5fu7A:
undetectable		 5y2tB-5fu7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 8 HIS A2282
PHE A2284
HIS A2114
LEU A2220
 None
 1.03A 5y2tB-5fu7A:
undetectable		 5y2tB-5fu7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		4 / 7 LEU A1975
GLN A1976
LEU A2026
PHE A2034
 None
 0.98A 5zcqC-5fu7A:
2.8
5zcqJ-5fu7A:
undetectable		 5zcqC-5fu7A:
18.30
5zcqJ-5fu7A:
7.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 5fu7 CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 1
(Homo
sapiens) 		5 / 10 LEU A2016
LEU A1963
THR A2022
ASN A2021
PHE A2023
 None
 1.18A 6hupD-5fu7A:
1.9
6hupE-5fu7A:
4.1		 6hupD-5fu7A:
11.88
6hupE-5fu7A:
9.19