SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fuc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 5fuc INTERLEUKIN-6
RECEPTOR SUBUNIT
ALPHA, INTERLEUKIN-6
RECEPTOR
(Homo
sapiens) 		3 / 3 TRP C 264
THR C 247
TYR C 238
 None
 1.29A 2a3bA-5fucC:
undetectable		 2a3bA-5fucC:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 5fuc INTERLEUKIN-6
RECEPTOR SUBUNIT
ALPHA, INTERLEUKIN-6
RECEPTOR
VHH6
(Camelus
dromedarius;
Homo
sapiens) 		3 / 3 ASN C 226
TYR E  59
SER C 228
 NAG  C1299 (-1.8A)
None
None
 0.86A 2gvcB-5fucC:
undetectable		 2gvcB-5fucC:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 5fuc INTERLEUKIN-6
RECEPTOR SUBUNIT
ALPHA, INTERLEUKIN-6
RECEPTOR
VHH6
(Camelus
dromedarius;
Homo
sapiens) 		3 / 3 ASN C 226
TYR E  59
SER C 228
 NAG  C1299 (-1.8A)
None
None
 0.84A 2gvcE-5fucC:
undetectable		 2gvcE-5fucC:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 5fuc VHH6
(Camelus
dromedarius) 		5 / 12 GLY E 116
GLN E 117
ASN E  21
LEU E  81
THR E 119
 None
 1.17A 3eeyE-5fucE:
undetectable		 3eeyE-5fucE:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 5fuc VHH6
(Camelus
dromedarius) 		5 / 12 GLN E 117
GLU E   6
PHE E  37
GLY E  35
GLY E 116
 None
 1.15A 3tegA-5fucE:
undetectable		 3tegA-5fucE:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 5fuc INTERLEUKIN-6
RECEPTOR SUBUNIT
ALPHA, INTERLEUKIN-6
RECEPTOR
(Homo
sapiens) 		4 / 7 VAL C 161
LEU C 129
LEU C 195
GLY C 191
 None
 0.76A 6eu9D-5fucC:
undetectable		 6eu9D-5fucC:
15.98