SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		5 / 9 ALA A  54
ALA A  47
GLY A  48
GLY A  78
ILE A  86
 None
 1.25A 2v7bA-5fudA:
2.1		 2v7bA-5fudA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		5 / 9 ALA A  54
ALA A  47
GLY A  48
GLY A  78
ILE A  86
 None
 1.30A 2v7bB-5fudA:
undetectable		 2v7bB-5fudA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 8 GLY A  36
GLY A  41
HIS A  44
ILE A  43
 MES  A1188 ( 3.7A)
None
None
None
 0.65A 3d41A-5fudA:
undetectable		 3d41A-5fudA:
26.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_A_ACTA601_0
(CHOLINE OXIDASE)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 5 ILE A  43
HIS A  44
HIS A  88
ASN A  27
 None
 1.03A 3nneA-5fudA:
undetectable		 3nneA-5fudA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 6 ALA A  47
ILE A  43
HIS A  88
ASN A  27
 None
 1.17A 3nneG-5fudA:
undetectable		 3nneG-5fudA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 6 ILE A  43
HIS A  44
HIS A  88
ASN A  27
 None
 1.09A 3nneG-5fudA:
undetectable		 3nneG-5fudA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		5 / 12 ILE A  75
VAL A 163
ILE A  43
VAL A  39
VAL A 164
 None
 1.25A 3w68C-5fudA:
undetectable		 3w68C-5fudA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H4D_A_BBIA403_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 6 PHE A 152
PHE A 126
GLU A  72
VAL A  73
 None
 1.32A 5h4dA-5fudA:
undetectable		 5h4dA-5fudA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 6 ILE A  87
GLY A  31
ASN A  30
ILE A  74
 None
None
MES  A1188 (-4.1A)
None
 0.97A 5j4nB-5fudA:
undetectable		 5j4nB-5fudA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 6 ARG A  84
PHE A  79
ILE A  43
THR A  18
 None
 1.12A 5vceA-5fudA:
undetectable		 5vceA-5fudA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5fud O-ACETYL-ADP-RIBOSE
DEACETYLASE
(Oceanobacillus
iheyensis) 		4 / 8 ILE A  93
THR A  89
VAL A  73
GLU A  72
 None
 1.17A 6fbvC-5fudA:
undetectable		 6fbvC-5fudA:
11.16