SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		5 / 12 VAL A 360
ILE A 383
TYR A 315
ILE A 378
LEU A 330
 None
 1.24A 1fm4A-5fuiA:
undetectable		 1fm4A-5fuiA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		3 / 3 GLU A 280
ASN A 377
TRP A 351
 GOL  A 131 (-2.8A)
GOL  A 131 (-2.9A)
None
 1.22A 1r15C-5fuiA:
undetectable		 1r15C-5fuiA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		3 / 3 GLU A 280
ASN A 377
TRP A 351
 GOL  A 131 (-2.8A)
GOL  A 131 (-2.9A)
None
 1.27A 1r15D-5fuiA:
undetectable		 1r15D-5fuiA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		3 / 3 GLU A 280
ASN A 377
TRP A 351
 GOL  A 131 (-2.8A)
GOL  A 131 (-2.9A)
None
 1.25A 1r15E-5fuiA:
undetectable		 1r15E-5fuiA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		3 / 3 GLU A 280
ASN A 377
TRP A 351
 GOL  A 131 (-2.8A)
GOL  A 131 (-2.9A)
None
 1.25A 1r15F-5fuiA:
undetectable		 1r15F-5fuiA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		4 / 7 ASP A 329
SER A 327
SER A 371
ASP A 276
 APY  A 132 (-2.7A)
None
None
None
 1.34A 3bc9A-5fuiA:
undetectable		 3bc9A-5fuiA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_A_ACTA1358_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		5 / 9 ALA A 320
GLY A 324
VAL A 342
ASN A 344
SER A 319
 None
 1.33A 4a3uA-5fuiA:
undetectable		 4a3uA-5fuiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		5 / 12 VAL A 317
GLN A 356
THR A 357
VAL A 358
ILE A 383
 None
 1.33A 4s0vA-5fuiA:
undetectable		 4s0vA-5fuiA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 5fui ENDO-1,3-BETA-GLUCAN
ASE, FAMILY GH16
(Zobellia
galactanivorans) 		5 / 9 VAL A 358
VAL A 360
PHE A 305
ILE A 303
PHE A 367
 None
 1.46A 5e4dA-5fuiA:
undetectable		 5e4dA-5fuiA:
22.97