SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fux'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 5fux THYMDINE KINASE
(Trypanosoma
brucei) 		5 / 9 GLY A 287
ASP A 285
ILE A 308
ILE A 211
ILE A 207
 None
MG  A1385 ( 4.3A)
None
None
None
 0.91A 3s53A-5fuxA:
undetectable		 3s53A-5fuxA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 5fux THYMDINE KINASE
(Trypanosoma
brucei) 		5 / 12 GLY A 287
ASP A 285
ILE A 308
ILE A 211
ILE A 207
 None
MG  A1385 ( 4.3A)
None
None
None
 0.93A 3s56A-5fuxA:
undetectable		 3s56A-5fuxA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 5fux THYMDINE KINASE
(Trypanosoma
brucei) 		5 / 12 ARG A 228
GLU A 221
ARG A 224
GLU A 208
ARG A 206
 None
 1.09A 6ekuA-5fuxA:
undetectable		 6ekuA-5fuxA:
14.21