SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fv4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AX9_A_EDRA999_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 GLY A 125
GLU A 203
SER A 204
HIS A 449
None
0.68A 1ax9A-5fv4A:
51.6
1ax9A-5fv4A:
37.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 ASP A  73
GLY A 124
GLY A 125
GLY A 126
PHE A 300
None
0.68A 1dx6A-5fv4A:
52.9
1dx6A-5fv4A:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 GLY A 124
GLY A 125
GLY A 126
SER A 204
PHE A 300
HIS A 449
None
0.52A 1dx6A-5fv4A:
52.9
1dx6A-5fv4A:
37.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 PHE A 337
MET A 402
PHE A 398
LEU A 288
None
1.25A 1ea1A-5fv4A:
undetectable
1ea1A-5fv4A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 207
VAL A 210
ILE A 122
TYR A 153
GLY A 124
None
1.40A 1fohA-5fv4A:
undetectable
1fohA-5fv4A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 207
VAL A 210
ILE A 122
TYR A 153
GLY A 124
None
1.41A 1fohB-5fv4A:
undetectable
1fohB-5fv4A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 207
VAL A 210
ILE A 122
TYR A 153
GLY A 124
None
1.38A 1fohC-5fv4A:
undetectable
1fohC-5fv4A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 207
VAL A 210
ILE A 122
TYR A 153
GLY A 124
None
1.40A 1fohD-5fv4A:
undetectable
1fohD-5fv4A:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 7 MET A 345
PHE A 286
SER A 204
ILE A 369
None
0.90A 1fxhA-5fv4A:
undetectable
1fxhB-5fv4A:
undetectable
1fxhA-5fv4A:
18.23
1fxhB-5fv4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_A_NIOA704_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 4 SER A 230
PHE A 430
GLU A 336
GLY A 447
None
1.40A 1icvA-5fv4A:
undetectable
1icvB-5fv4A:
undetectable
1icvA-5fv4A:
17.49
1icvB-5fv4A:
17.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 125
GLU A 203
SER A 204
PHE A 286
HIS A 449
None
1.08A 1maaA-5fv4A:
45.5
1maaA-5fv4A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_A_DMEA998_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 125
GLU A 203
SER A 204
PHE A 300
HIS A 449
None
0.67A 1maaA-5fv4A:
45.5
1maaA-5fv4A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_C_DMEC997_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 125
TYR A 135
SER A 204
PHE A 300
HIS A 449
None
0.73A 1maaC-5fv4A:
50.4
1maaC-5fv4A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 GLY A 125
GLU A 203
SER A 204
HIS A 449
None
0.32A 1maaD-5fv4A:
45.3
1maaD-5fv4A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 GLY A 126
GLU A 203
SER A 204
HIS A 449
None
0.84A 1maaD-5fv4A:
45.3
1maaD-5fv4A:
35.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
7 / 11 PHE A  84
GLY A 125
GLY A 126
SER A 204
LEU A 238
MET A 345
HIS A 449
None
0.43A 1mx1A-5fv4A:
67.0
1mx1A-5fv4A:
78.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 PHE A  84
GLY A 125
LEU A 238
LEU A 340
HIS A 449
None
1.30A 1mx1B-5fv4A:
66.4
1mx1B-5fv4A:
78.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 PHE A  84
GLY A 125
SER A 204
LEU A 340
HIS A 449
None
0.17A 1mx1B-5fv4A:
66.4
1mx1B-5fv4A:
78.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 GLY A 125
SER A 204
THR A 235
LEU A 238
PHE A 407
HIS A 449
None
0.62A 1mx1C-5fv4A:
66.9
1mx1C-5fv4A:
78.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 GLY A 125
VAL A 128
SER A 204
MET A 345
PHE A 407
HIS A 449
None
1.26A 1mx1E-5fv4A:
67.2
1mx1E-5fv4A:
78.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 GLY A 125
VAL A 129
SER A 204
MET A 345
PHE A 407
HIS A 449
None
0.35A 1mx1E-5fv4A:
67.2
1mx1E-5fv4A:
78.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 126
VAL A 128
SER A 204
MET A 345
HIS A 449
None
0.92A 1mx1E-5fv4A:
67.2
1mx1E-5fv4A:
78.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
7 / 12 GLY A 125
GLY A 126
SER A 204
LEU A 238
MET A 345
PHE A 407
HIS A 449
None
0.48A 1mx1F-5fv4A:
66.6
1mx1F-5fv4A:
78.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 4 SER A 204
VAL A 406
PHE A 286
VAL A 128
None
1.38A 1o86A-5fv4A:
undetectable
1o86A-5fv4A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 6 PHE A 430
ASN A 333
ILE A 453
GLY A 450
None
1.01A 1oniA-5fv4A:
1.3
1oniB-5fv4A:
1.1
1oniA-5fv4A:
14.88
1oniB-5fv4A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 6 PHE A 430
ASN A 333
ILE A 453
GLY A 450
None
1.02A 1oniD-5fv4A:
1.1
1oniF-5fv4A:
1.2
1oniD-5fv4A:
14.88
1oniF-5fv4A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 7 ILE A 453
GLY A 450
PHE A 430
ASN A 333
None
1.00A 1oniG-5fv4A:
1.3
1oniI-5fv4A:
undetectable
1oniG-5fv4A:
14.88
1oniI-5fv4A:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 207
VAL A 210
ILE A 122
TYR A 153
GLY A 124
None
1.39A 1pn0C-5fv4A:
undetectable
1pn0C-5fv4A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 207
VAL A 210
ILE A 122
TYR A 153
GLY A 124
None
1.39A 1pn0D-5fv4A:
undetectable
1pn0D-5fv4A:
23.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 ASP A  73
GLY A 124
GLY A 125
GLY A 126
PHE A 300
None
0.64A 1qtiA-5fv4A:
51.8
1qtiA-5fv4A:
37.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1QTI_A_GNTA600_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
7 / 12 GLY A 124
GLY A 125
GLY A 126
GLU A 203
SER A 204
PHE A 300
HIS A 449
None
0.54A 1qtiA-5fv4A:
51.8
1qtiA-5fv4A:
37.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 PRO A 107
GLY A 114
ILE A 104
VAL A 146
GLY A 193
GLY A 192
None
1.18A 1uakA-5fv4A:
undetectable
1uakA-5fv4A:
20.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 ASP A  73
GLY A 124
GLY A 125
GLY A 126
PHE A 300
None
0.70A 1w6rA-5fv4A:
52.8
1w6rA-5fv4A:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W6R_A_GNTA1536_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 GLY A 124
GLY A 125
GLY A 126
SER A 204
PHE A 300
HIS A 449
None
0.55A 1w6rA-5fv4A:
52.8
1w6rA-5fv4A:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 11 GLY A 125
GLY A 126
GLU A 203
SER A 204
PHE A 300
HIS A 449
None
0.49A 1w76A-5fv4A:
52.6
1w76A-5fv4A:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 10 GLY A 124
GLY A 125
GLU A 203
SER A 204
PHE A 300
HIS A 449
None
0.46A 1w76B-5fv4A:
52.5
1w76B-5fv4A:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 206
GLU A 203
SER A 204
PHE A 300
HIS A 449
None
1.22A 1w76B-5fv4A:
52.5
1w76B-5fv4A:
37.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 5 TRP A 481
ILE A 227
LEU A 140
ALA A 482
None
0.96A 1xvaA-5fv4A:
undetectable
1xvaB-5fv4A:
undetectable
1xvaA-5fv4A:
18.81
1xvaB-5fv4A:
18.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA11_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 TRP A 339
PRO A 342
GLY A 352
LEU A 399
None
0.46A 1ya4A-5fv4A:
66.5
1ya4A-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA11_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 8 TRP A 339
PRO A 342
LEU A 349
LEU A 399
PRO A 442
None
0.59A 1ya4A-5fv4A:
66.5
1ya4A-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_A_CTXA1_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
7 / 12 ALA A  76
PHE A  84
GLY A 125
GLY A 126
SER A 204
MET A 345
HIS A 449
None
0.59A 1ya4A-5fv4A:
66.5
1ya4A-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 7 PRO A 342
LEU A 349
GLY A 352
LYS A 395
LEU A 399
PRO A 442
None
1.18A 1ya4B-5fv4A:
63.3
1ya4B-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 7 TRP A 339
PRO A 342
LEU A 349
GLY A 352
LEU A 399
PRO A 442
None
0.70A 1ya4B-5fv4A:
63.3
1ya4B-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_B_CTXB2_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 PHE A  84
GLY A 125
GLY A 126
SER A 204
LEU A 340
HIS A 449
None
0.38A 1ya4B-5fv4A:
63.3
1ya4B-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 5 PRO A 342
LEU A 349
GLY A 352
LYS A 395
None
1.40A 1ya4C-5fv4A:
66.5
1ya4C-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 5 TRP A 339
PRO A 342
LEU A 349
GLY A 352
None
0.74A 1ya4C-5fv4A:
66.5
1ya4C-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA4_C_CTXC3_1
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
7 / 12 PHE A  84
GLY A 125
GLY A 126
SER A 204
LEU A 340
MET A 345
HIS A 449
None
0.55A 1ya4C-5fv4A:
66.5
1ya4C-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 TRP A 339
LEU A 349
LYS A 395
None
0.94A 1yajK-5fv4A:
64.8
1yajK-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAJ_K_BEZK4387_0
(CES1 PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 TRP A 339
LEU A 399
LYS A 395
None
1.38A 1yajK-5fv4A:
64.8
1yajK-5fv4A:
78.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 9 GLY A 124
GLY A 125
SER A 204
ALA A 205
HIS A 449
None
0.82A 2aceA-5fv4A:
53.2
2aceA-5fv4A:
37.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 9 GLY A 125
GLY A 126
SER A 204
ALA A 205
PHE A 286
HIS A 449
None
1.04A 2aceA-5fv4A:
53.2
2aceA-5fv4A:
37.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACE_A_ACHA998_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 9 GLY A 125
GLY A 126
SER A 204
ALA A 205
PHE A 300
HIS A 449
None
0.61A 2aceA-5fv4A:
53.2
2aceA-5fv4A:
37.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 7 GLY A 125
GLU A 203
SER A 204
HIS A 449
None
0.73A 2ackA-5fv4A:
53.3
2ackA-5fv4A:
37.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 7 LEU A 399
PRO A 342
GLY A 450
ASP A 451
None
0.69A 2ddwB-5fv4A:
undetectable
2ddwB-5fv4A:
20.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DQY_A_CHDA1_0
(LIVER
CARBOXYLESTERASE 1)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 5 TRP A 339
GLY A 352
LYS A 395
LEU A 399
PRO A 442
None
1.08A 2dqyA-5fv4A:
66.4
2dqyA-5fv4A:
79.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 TRP A 339
LYS A 395
PRO A 442
None
0.76A 2dqyB-5fv4A:
66.5
2dqyB-5fv4A:
79.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 6 TRP A 339
LEU A 349
LYS A 395
LEU A 399
PRO A 442
VAL A 445
None
0.83A 2dqyC-5fv4A:
66.5
2dqyC-5fv4A:
79.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 9 GLN A 177
GLY A 207
GLU A 203
ALA A 233
VAL A 239
None
1.26A 2drdA-5fv4A:
undetectable
2drdA-5fv4A:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 TYR A 135
GLU A 203
HIS A 449
GLY A 450
None
0.28A 2ha4A-5fv4A:
50.0
2ha4A-5fv4A:
35.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 8 GLY A 125
GLY A 126
ALA A 205
PHE A 286
HIS A 449
None
1.19A 2ha4A-5fv4A:
50.1
2ha4A-5fv4A:
35.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_A_ACTA544_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 8 GLY A 125
GLY A 126
ALA A 205
PHE A 300
HIS A 449
None
0.65A 2ha4A-5fv4A:
50.1
2ha4A-5fv4A:
35.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 7 TYR A 135
GLU A 203
HIS A 449
GLY A 450
None
0.23A 2ha4B-5fv4A:
51.4
2ha4B-5fv4A:
35.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 7 GLY A 125
GLY A 126
ALA A 205
PHE A 286
HIS A 449
None
1.21A 2ha4B-5fv4A:
51.4
2ha4B-5fv4A:
35.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 7 GLY A 125
GLY A 126
ALA A 205
PHE A 300
HIS A 449
None
0.65A 2ha4B-5fv4A:
51.4
2ha4B-5fv4A:
35.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 PHE A 160
LEU A 127
SER A 209
LEU A 340
HIS A 449
None
1.37A 2hc4A-5fv4A:
undetectable
2hc4A-5fv4A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 ALA A 421
ALA A 219
ILE A 317
PHE A 223
TYR A 328
None
1.17A 2nyrA-5fv4A:
undetectable
2nyrA-5fv4A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLU A 203
PHE A  84
ILE A 200
LEU A 213
GLY A 207
None
1.32A 2ogyA-5fv4A:
2.1
2ogyA-5fv4A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 LEU A 341
PRO A 410
SER A 411
GLY A 237
None
1.10A 2qd5B-5fv4A:
3.1
2qd5B-5fv4A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 5 THR A 413
ARG A 416
ALA A 415
ARG A 419
None
1.16A 2qhfA-5fv4A:
undetectable
2qhfA-5fv4A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 LEU A 100
ILE A 151
ALA A 132
GLU A 208
LEU A 155
None
1.38A 2v0mA-5fv4A:
undetectable
2v0mA-5fv4A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 TYR A 153
GLU A 203
ASP A 448
None
0.85A 3bxoA-5fv4A:
undetectable
3bxoA-5fv4A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 ASN A  86
ASP A  82
GLN A  78
None
0.78A 3eeyC-5fv4A:
undetectable
3eeyC-5fv4A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 ASN A  86
ASP A  82
GLN A  78
None
0.78A 3eeyD-5fv4A:
undetectable
3eeyD-5fv4A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 ASN A  86
ASP A  82
GLN A  78
None
0.76A 3eeyE-5fv4A:
undetectable
3eeyE-5fv4A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC151_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 ILE A 453
VAL A 456
GLY A 458
TYR A 105
ARG A  87
None
1.16A 3elzC-5fv4A:
undetectable
3elzC-5fv4A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_1
(GLUCOCORTICOID
RECEPTOR)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 ASN A 333
TRP A 481
GLN A 509
LEU A 508
TYR A 507
None
1.33A 3h52B-5fv4A:
undetectable
3h52B-5fv4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 8 LEU A 341
PRO A 410
SER A 411
GLY A 237
None
1.12A 3hcrA-5fv4A:
2.9
3hcrA-5fv4A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 7 LEU A 341
PRO A 410
SER A 411
GLY A 237
None
1.09A 3hcrB-5fv4A:
3.3
3hcrB-5fv4A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 6 PHE A 161
ILE A 250
ALA A 247
THR A 258
None
1.05A 3mdrB-5fv4A:
undetectable
3mdrB-5fv4A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 PRO A  37
LEU A  34
VAL A  32
ALA A  31
PHE A 191
None
1.37A 3n23C-5fv4A:
1.4
3n23C-5fv4A:
21.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_A_BEZA999_0
(CHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 7 GLY A 125
GLY A 126
SER A 204
PHE A 407
HIS A 449
None
0.39A 3o9mA-5fv4A:
52.8
3o9mA-5fv4A:
33.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O9M_B_BEZB999_0
(CHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 6 GLY A 125
GLY A 126
SER A 204
HIS A 449
None
0.38A 3o9mB-5fv4A:
52.8
3o9mB-5fv4A:
33.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_A_GNTA604_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
6 / 12 GLY A 124
GLY A 125
GLY A 126
SER A 204
PHE A 300
HIS A 449
None
0.49A 4ey6A-5fv4A:
51.1
4ey6A-5fv4A:
36.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY6_B_GNTB605_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
7 / 12 GLY A 124
GLY A 125
GLY A 126
GLU A 203
SER A 204
PHE A 300
HIS A 449
None
0.52A 4ey6B-5fv4A:
45.7
4ey6B-5fv4A:
36.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 125
GLU A 203
SER A 204
HIS A 449
GLY A 450
None
0.69A 4ey7A-5fv4A:
50.8
4ey7A-5fv4A:
36.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 125
GLU A 203
SER A 204
HIS A 449
GLY A 450
None
0.72A 4ey7B-5fv4A:
50.4
4ey7B-5fv4A:
36.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 192
GLY A 193
VAL A  30
PHE A  33
ILE A 104
None
1.28A 4fglA-5fv4A:
2.1
4fglB-5fv4A:
2.9
4fglA-5fv4A:
17.88
4fglB-5fv4A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 VAL A 252
GLY A 255
LYS A 257
None
0.54A 4k50I-5fv4A:
undetectable
4k50I-5fv4A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 HIS A 449
TRP A 339
SER A 204
None
1.12A 4lrhD-5fv4A:
undetectable
4lrhD-5fv4A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 LEU A 155
GLY A 126
THR A 280
ILE A 157
PHE A 285
None
1.42A 4p6xA-5fv4A:
undetectable
4p6xA-5fv4A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 LEU A 155
GLY A 126
THR A 280
ILE A 157
PHE A 285
None
1.44A 4p6xE-5fv4A:
undetectable
4p6xE-5fv4A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 5 ILE A  92
PRO A  93
HIS A 123
TYR A 105
None
1.24A 4s0vA-5fv4A:
undetectable
4s0vA-5fv4A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 LEU A 155
GLY A 126
THR A 280
ILE A 157
PHE A 285
None
1.44A 4udcA-5fv4A:
undetectable
4udcA-5fv4A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 5 PHE A 454
HIS A 449
LEU A  83
PRO A 434
None
1.16A 5csyB-5fv4A:
undetectable
5csyB-5fv4A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 231
GLY A 126
GLY A 124
GLY A 207
ASP A  73
None
0.91A 5kqsA-5fv4A:
undetectable
5kqsA-5fv4A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 231
GLY A 126
GLY A 124
GLY A 207
ASP A  73
None
0.91A 5m5bA-5fv4A:
undetectable
5m5bA-5fv4A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 12 GLY A 231
GLY A 126
GLY A 124
GLY A 207
ASP A  73
None
0.90A 5wz2A-5fv4A:
undetectable
5wz2A-5fv4A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
3 / 3 GLU A 452
TRP A 121
HIS A 449
None
0.88A 5xipA-5fv4A:
undetectable
5xipA-5fv4A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
4 / 5 GLN A  78
VAL A  75
PRO A  93
THR A 280
None
1.37A 6cduI-5fv4A:
undetectable
6cduJ-5fv4A:
undetectable
6cduI-5fv4A:
20.27
6cduJ-5fv4A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 125
LEU A 238
ALA A 236
PHE A 286
HIS A 449
None
1.00A 6qgbA-5fv4A:
10.5
6qgbA-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 125
SER A 204
LEU A 238
PHE A 286
HIS A 449
None
0.79A 6qgbA-5fv4A:
10.5
6qgbA-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 126
SER A 204
PHE A 286
PHE A 407
HIS A 449
None
1.01A 6qgbA-5fv4A:
10.5
6qgbA-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 126
SER A 204
PHE A 300
PHE A 407
HIS A 449
None
1.38A 6qgbA-5fv4A:
10.5
6qgbA-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 125
LEU A 238
ALA A 236
PHE A 286
HIS A 449
None
0.98A 6qgbB-5fv4A:
10.6
6qgbB-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 125
SER A 204
LEU A 238
PHE A 286
HIS A 449
None
0.80A 6qgbB-5fv4A:
10.6
6qgbB-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 126
SER A 204
PHE A 286
PHE A 407
HIS A 449
None
1.02A 6qgbB-5fv4A:
10.6
6qgbB-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 126
SER A 204
PHE A 300
PHE A 407
HIS A 449
None
1.38A 6qgbB-5fv4A:
10.6
6qgbB-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_C_BEZC701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 9 GLY A 125
SER A 204
LEU A 238
PHE A 286
HIS A 449
None
0.82A 6qgbC-5fv4A:
11.2
6qgbC-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_C_BEZC701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 9 GLY A 126
SER A 204
PHE A 286
PHE A 407
HIS A 449
None
0.98A 6qgbC-5fv4A:
11.2
6qgbC-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_C_BEZC701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 9 GLY A 126
SER A 204
PHE A 300
PHE A 407
HIS A 449
None
1.36A 6qgbC-5fv4A:
11.2
6qgbC-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 125
LEU A 238
ALA A 236
PHE A 286
HIS A 449
None
0.99A 6qgbD-5fv4A:
2.9
6qgbD-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 125
SER A 204
LEU A 238
PHE A 286
HIS A 449
None
0.81A 6qgbD-5fv4A:
2.9
6qgbD-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 126
SER A 204
PHE A 286
PHE A 407
HIS A 449
None
1.02A 6qgbD-5fv4A:
2.9
6qgbD-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 126
SER A 204
PHE A 300
PHE A 407
HIS A 449
None
1.37A 6qgbD-5fv4A:
2.9
6qgbD-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 125
LEU A 238
ALA A 236
PHE A 286
HIS A 449
None
0.99A 6qgbE-5fv4A:
11.6
6qgbE-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 125
SER A 204
LEU A 238
PHE A 286
HIS A 449
None
0.82A 6qgbE-5fv4A:
11.6
6qgbE-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 126
SER A 204
PHE A 286
PHE A 407
HIS A 449
None
1.02A 6qgbE-5fv4A:
11.6
6qgbE-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 11 GLY A 126
SER A 204
PHE A 300
PHE A 407
HIS A 449
None
1.38A 6qgbE-5fv4A:
11.6
6qgbE-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 125
LEU A 238
ALA A 236
PHE A 286
HIS A 449
None
0.99A 6qgbF-5fv4A:
5.5
6qgbF-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 125
SER A 204
LEU A 238
PHE A 286
HIS A 449
None
0.81A 6qgbF-5fv4A:
5.5
6qgbF-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 126
SER A 204
PHE A 286
PHE A 407
HIS A 449
None
0.99A 6qgbF-5fv4A:
5.5
6qgbF-5fv4A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus
scrofa)
5 / 10 GLY A 126
SER A 204
PHE A 300
PHE A 407
HIS A 449
None
1.39A 6qgbF-5fv4A:
5.5
6qgbF-5fv4A:
22.61