SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fv5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 5fv5 KPFLO11A1
(Komagataella
phaffii) 		3 / 3 ALA A  36
VAL A 131
TRP A 184
 None
 0.90A 1jnoA-5fv5A:
undetectable		 1jnoA-5fv5A:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 5fv5 KPFLO11A1
(Komagataella
phaffii) 		3 / 3 ALA A  36
VAL A 131
TRP A 184
 None
 0.89A 1jnoB-5fv5A:
undetectable		 1jnoB-5fv5A:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 5fv5 KPFLO11A1
(Komagataella
phaffii) 		3 / 3 ALA A  36
VAL A 131
TRP A 184
 None
 0.92A 1ng8A-5fv5A:
undetectable		 1ng8A-5fv5A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 5fv5 KPFLO11A1
(Komagataella
phaffii) 		3 / 3 ALA A  36
VAL A 131
TRP A 184
 None
 0.92A 1ng8B-5fv5A:
undetectable		 1ng8B-5fv5A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 5fv5 KPFLO11A1
(Komagataella
phaffii) 		4 / 7 VAL A 140
TYR A 161
GLU A  73
PRO A  47
 ACT  A1193 (-4.9A)
None
None
None
 1.12A 3hs4A-5fv5A:
undetectable		 3hs4A-5fv5A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5fv5 KPFLO11A1
(Komagataella
phaffii) 		4 / 7 ASP A  65
GLY A  55
THR A  54
ILE A  53
 None
 0.79A 4acaC-5fv5A:
undetectable		 4acaC-5fv5A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 5fv5 KPFLO11A1
(Komagataella
phaffii) 		4 / 7 LYS A  84
LEU A  97
GLU A  82
SER A 100
 None
 1.14A 4tvtA-5fv5A:
undetectable		 4tvtA-5fv5A:
25.12