SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fvd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		4 / 6 TYR A 198
ILE A 146
PRO A 147
ARG A 197
 None
 1.33A 1oniA-5fvdA:
undetectable
1oniC-5fvdA:
undetectable		 1oniA-5fvdA:
16.94
1oniC-5fvdA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		5 / 12 ILE A  67
ALA A  63
PHE A 214
LEU A 213
VAL A  79
 None
 1.01A 3dzyA-5fvdA:
undetectable		 3dzyA-5fvdA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		5 / 12 LEU A 371
GLY A 370
LEU A 369
ILE A 334
ALA A 265
 None
 0.99A 3gwvA-5fvdA:
undetectable		 3gwvA-5fvdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		5 / 12 LEU A 371
GLY A 370
LEU A 369
ILE A 334
ALA A 265
 None
 1.04A 3gwwA-5fvdA:
undetectable		 3gwwA-5fvdA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A302_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		5 / 12 GLN A  41
ILE A  44
GLN A  68
ILE A 116
ALA A  34
 None
 1.06A 4ltwA-5fvdA:
undetectable		 4ltwA-5fvdA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		5 / 12 LEU A 223
ILE A  82
LEU A  83
GLY A  75
VAL A  92
 None
 0.87A 4nkvB-5fvdA:
undetectable		 4nkvB-5fvdA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		3 / 3 PRO A 158
LEU A 161
HIS A  56
 None
 0.70A 4pevA-5fvdA:
undetectable		 4pevA-5fvdA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_H_Z80H401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		5 / 10 ILE A 203
ILE A 206
VAL A 184
ASP A 212
ILE A 168
 None
 1.22A 5lg3H-5fvdA:
undetectable		 5lg3H-5fvdA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5fvd NUCLEOCAPSID
(Human
metapneumovirus) 		4 / 6 LEU A 302
ILE A 176
THR A 175
TRP A 261
 None
 1.29A 5ljeA-5fvdA:
undetectable		 5ljeA-5fvdA:
14.83