SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fw4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 12 GLY A 150
ALA A  99
SER A 100
MET A 102
GLY A 180
 None
 1.23A 1nbiC-5fw4A:
undetectable		 1nbiC-5fw4A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 12 GLY A 150
ALA A  99
SER A 100
MET A 102
GLY A 180
 None
 1.23A 1nbiD-5fw4A:
undetectable		 1nbiD-5fw4A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 10 ALA A  29
VAL A 375
GLN A 148
GLN A 210
PHE A 215
 None
 1.14A 1rlbE-5fw4A:
undetectable		 1rlbE-5fw4A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 11 PHE A 336
VAL A 239
GLY A 346
LEU A 128
PHE A 131
 HEM  A 401 ( 4.0A)
None
None
None
None
 0.84A 1z11A-5fw4A:
undetectable		 1z11A-5fw4A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 11 PHE A 336
VAL A 239
GLY A 346
LEU A 128
PHE A 131
 HEM  A 401 ( 4.0A)
None
None
None
None
 0.84A 1z11B-5fw4A:
undetectable		 1z11B-5fw4A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_C_8MOC501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 10 PHE A 336
VAL A 239
GLY A 346
LEU A 128
PHE A 131
 HEM  A 401 ( 4.0A)
None
None
None
None
 0.86A 1z11C-5fw4A:
undetectable		 1z11C-5fw4A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 10 PHE A 336
VAL A 239
GLY A 346
LEU A 128
PHE A 131
 HEM  A 401 ( 4.0A)
None
None
None
None
 0.85A 1z11D-5fw4A:
undetectable		 1z11D-5fw4A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 11 LEU A  75
VAL A 156
ALA A 159
LEU A 157
LEU A  79
 None
 1.33A 2c12F-5fw4A:
undetectable		 2c12F-5fw4A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 12 LEU A 111
LEU A 112
GLY A 109
VAL A 375
ALA A  47
 None
 0.95A 2oz7A-5fw4A:
undetectable		 2oz7A-5fw4A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		4 / 8 MET A 146
ARG A 316
VAL A  43
GLY A 150
 None
 0.98A 2qd3A-5fw4A:
undetectable		 2qd3A-5fw4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA701_0
(FERROCHELATASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		4 / 8 MET A 146
ARG A 316
VAL A  43
GLY A 150
 None
 0.87A 2qd5A-5fw4A:
undetectable		 2qd5A-5fw4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 12 ALA A 377
PRO A 376
GLN A 210
PHE A 215
ILE A 219
 None
 1.28A 2v95A-5fw4A:
undetectable		 2v95A-5fw4A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 11 ALA A  29
VAL A 375
GLN A 148
GLN A 210
PHE A 215
 None
 1.20A 3bszE-5fw4A:
undetectable		 3bszE-5fw4A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		4 / 4 LEU A 384
ALA A  76
VAL A 103
PRO A  33
 None
 1.11A 3gv1B-5fw4A:
undetectable		 3gv1B-5fw4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 11 PHE A 336
VAL A 239
GLY A 346
LEU A 128
PHE A 131
 HEM  A 401 ( 4.0A)
None
None
None
None
 0.78A 3t3rA-5fw4A:
undetectable		 3t3rA-5fw4A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_D_C2FD302_0
(THYMIDYLATE SYNTHASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 11 ILE A  46
LEU A  75
LEU A 157
GLY A 150
ALA A 159
 None
 1.25A 4fogD-5fw4A:
undetectable		 4fogD-5fw4A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		3 / 3 ASP A 356
ARG A 352
ASP A 134
 None
 0.84A 4fp9D-5fw4A:
undetectable		 4fp9D-5fw4A:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 12 PHE A 145
ALA A  47
MET A 146
LEU A  69
LEU A 112
 None
 1.10A 4kykA-5fw4A:
undetectable
4kykB-5fw4A:
undetectable		 4kykA-5fw4A:
17.36
4kykB-5fw4A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		3 / 3 SER A 177
ASP A 331
ASP A 326
 None
 0.79A 4mwzA-5fw4A:
undetectable		 4mwzA-5fw4A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		3 / 3 LEU A 111
ILE A 107
TYR A 383
 None
 0.69A 5uunB-5fw4A:
undetectable		 5uunB-5fw4A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1471_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		5 / 12 ARG A  62
GLY A 109
LEU A 112
GLU A 118
HIS A 229
 None
 1.27A 5x7pB-5fw4A:
undetectable		 5x7pB-5fw4A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		3 / 3 ASP A 356
ARG A 352
ASP A 134
 None
 0.85A 5zvgA-5fw4A:
undetectable		 5zvgA-5fw4A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5fw4 DYE-DECOLORIZING
PEROXIDASE TFU_3078
(Thermobifida
fusca) 		3 / 3 ASP A 356
ARG A 352
ASP A 134
 None
 0.84A 5zvgB-5fw4A:
undetectable		 5zvgB-5fw4A:
21.11