SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fwh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5fwh ESSC
(Geobacillus
thermodenitrific
ans) 		4 / 6 TYR A   8
GLY A  27
GLU A  31
GLU A  21
 None
 1.09A 3fpjA-5fwhA:
undetectable		 3fpjA-5fwhA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 5fwh ESSC
(Geobacillus
thermodenitrific
ans) 		5 / 10 ILE A  26
LEU A  17
SER A  89
PRO A  71
ILE A  86
 None
 1.13A 4g8zX-5fwhA:
undetectable		 4g8zX-5fwhA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 5fwh ESSC
(Geobacillus
thermodenitrific
ans) 		4 / 7 GLU A 105
SER A 124
ILE A 135
VAL A 133
 None
 1.10A 4tvtA-5fwhA:
undetectable		 4tvtA-5fwhA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 5fwh ESSC
(Geobacillus
thermodenitrific
ans) 		4 / 6 LEU A   4
TRP A   5
ARG A  72
GLY A  90
 None
 0.98A 5o4yF-5fwhA:
undetectable		 5o4yF-5fwhA:
7.56