SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fya'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  38
HIS A  39
VAL A  42
 None
 0.45A 1lqtB-5fyaA:
undetectable		 1lqtB-5fyaA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		3 / 3 ALA A  38
HIS A  39
VAL A  42
 None
 0.43A 1lquB-5fyaA:
2.0		 1lquB-5fyaA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 217
ASP A 221
LYS A 173
 None
 1.16A 1lquB-5fyaA:
2.0		 1lquB-5fyaA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  29
ALA A  57
ILE A  56
ALA A 184
LEU A 141
 None
 1.09A 1xp0A-5fyaA:
undetectable		 1xp0A-5fyaA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_A_ECNA1409_1
(CYTOCHROME P450 130)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 265
PRO A 215
THR A  59
GLY A  31
GLY A  32
 None
 1.18A 2uvnA-5fyaA:
undetectable		 2uvnA-5fyaA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 8 TYR A  73
MET A  85
ILE A  81
SER A  71
 None
 1.11A 2xytH-5fyaA:
undetectable		 2xytH-5fyaA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 7 TYR A  73
MET A  85
ILE A  81
SER A  71
 None
 1.08A 2xytI-5fyaA:
undetectable		 2xytI-5fyaA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  65
ASP A  47
ALA A  45
THR A 302
THR A 301
 None
 1.19A 3a35A-5fyaA:
undetectable		 3a35A-5fyaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  65
ASP A  47
ALA A  45
THR A 302
THR A 301
 None
 1.19A 3a35B-5fyaA:
undetectable		 3a35B-5fyaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  65
ASP A  47
ALA A  45
THR A 302
THR A 301
 None
 1.22A 3a3bA-5fyaA:
undetectable		 3a3bA-5fyaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  31
GLY A  58
LEU A  29
LEU A 293
ALA A  63
 None
 0.97A 3av6A-5fyaA:
undetectable		 3av6A-5fyaA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_C_CHDC150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 175
VAL A 229
ILE A 214
GLN A 264
THR A 267
 None
 1.45A 3elzC-5fyaA:
undetectable		 3elzC-5fyaA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 182
SER A 149
LEU A  68
SER A  71
 None
 1.18A 3ijxH-5fyaA:
undetectable		 3ijxH-5fyaA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 5 PRO A 182
SER A 149
LEU A  68
SER A  71
 None
 1.16A 3iluH-5fyaA:
undetectable		 3iluH-5fyaA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 6 TYR A  73
MET A  85
ILE A  81
SER A  71
 None
 1.03A 3pmzD-5fyaA:
undetectable		 3pmzD-5fyaA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 10 LEU A  37
ILE A 232
ILE A  40
GLY A  41
GLY A 297
 None
 1.03A 4fakA-5fyaA:
undetectable		 4fakA-5fyaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_A_SAMA602_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 234
GLY A 208
SER A  60
ILE A 168
GLY A 171
 None
 1.07A 4obwA-5fyaA:
2.4		 4obwA-5fyaA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 ASN A 234
GLY A 208
SER A  60
ILE A 168
GLY A 171
 None
 1.18A 4obwC-5fyaA:
undetectable		 4obwC-5fyaA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		6 / 12 GLY A  66
GLY A  67
GLY A  58
ALA A 163
ILE A 214
ASN A 213
 None
 1.23A 4rtmA-5fyaA:
undetectable		 4rtmA-5fyaA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 206
PHE A 176
THR A  59
ARG A 177
 None
 1.18A 4xe5A-5fyaA:
undetectable		 4xe5A-5fyaA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 5 SER A  71
ALA A  70
HIS A 147
LEU A  68
 None
 1.29A 5dzkb-5fyaA:
undetectable
5dzkp-5fyaA:
undetectable		 5dzkb-5fyaA:
23.46
5dzkp-5fyaA:
1.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 6 SER A  71
ALA A  70
HIS A 147
LEU A  68
 None
 1.26A 5dzkB-5fyaA:
undetectable
5dzkP-5fyaA:
undetectable		 5dzkB-5fyaA:
23.46
5dzkP-5fyaA:
1.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		4 / 5 SER A  71
ALA A  70
HIS A 147
LEU A  68
 None
 1.26A 5dzkc-5fyaA:
undetectable
5dzkq-5fyaA:
undetectable		 5dzkc-5fyaA:
23.46
5dzkq-5fyaA:
1.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  78
GLY A 297
PRO A 278
LEU A 279
LEU A  37
 None
 1.49A 5emlA-5fyaA:
undetectable		 5emlA-5fyaA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 9 ILE A 294
GLY A 297
THR A 301
LEU A  43
LEU A  46
 None
 1.45A 5fhzB-5fyaA:
2.6		 5fhzB-5fyaA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 232
ILE A  40
GLY A  41
GLY A 297
VAL A  65
 None
 1.02A 5twjB-5fyaA:
undetectable		 5twjB-5fyaA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_C_SAMC201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  37
ILE A 232
ILE A  40
GLY A  41
VAL A  65
 None
 0.87A 5twjC-5fyaA:
undetectable		 5twjC-5fyaA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 175
VAL A 164
GLY A  26
MET A 222
GLY A  67
 None
 1.20A 6brdC-5fyaA:
undetectable		 6brdC-5fyaA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 11 PRO A 182
SER A 149
LEU A  68
SER A  71
LEU A 157
 None
 1.22A 6dlzA-5fyaA:
undetectable
6dlzD-5fyaA:
2.5		 6dlzA-5fyaA:
13.50
6dlzD-5fyaA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 5fya PATATIN-LIKE
PROTEIN, PLPD
(Pseudomonas
aeruginosa) 		5 / 11 PRO A 182
SER A 149
LEU A  68
SER A  71
LEU A 157
 None
 1.22A 6dm1A-5fyaA:
2.7
6dm1D-5fyaA:
2.6		 6dm1A-5fyaA:
13.50
6dm1D-5fyaA:
13.50