SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5fyd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		3 / 3 LEU A  12
HIS A 125
ILE A 129
 None
 0.49A 1s9pB-5fydA:
undetectable		 1s9pB-5fydA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R6W_A_NFZA214_1
(FMN-DEPENDENT
NADH-AZOREDUCTASE 1)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		5 / 10 VAL A 138
PHE A  87
ASN A 140
GLY A  15
PHE A  67
 None
 1.36A 3r6wA-5fydA:
4.0
3r6wB-5fydA:
4.3		 3r6wA-5fydA:
23.25
3r6wB-5fydA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		5 / 12 ILE A  13
VAL A  91
SER A  89
ILE A 139
THR A 189
 None
 1.17A 3vrjA-5fydA:
undetectable
3vrjC-5fydA:
undetectable		 3vrjA-5fydA:
21.05
3vrjC-5fydA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7T_A_SAMA503_0
(BTRN)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		5 / 11 HIS A  95
THR A 188
LEU A 194
LEU A 198
SER A 196
 None
 1.43A 4m7tA-5fydA:
2.3		 4m7tA-5fydA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		4 / 6 GLY A 136
ASP A 134
ASP A  84
ASP A 180
 None
 1.00A 4uckB-5fydA:
4.8		 4uckB-5fydA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		5 / 12 GLY A  57
GLY A  21
ILE A  13
GLY A  31
GLY A  32
 None
 0.83A 5koxA-5fydA:
2.8		 5koxA-5fydA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		4 / 8 LEU A 186
ILE A 184
ALA A 221
PHE A  24
 None
 0.71A 5m0oC-5fydA:
undetectable		 5m0oC-5fydA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5fyd OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN
(Collinsella
aerofaciens) 		5 / 10 THR A  75
CYH A 122
VAL A  38
ALA A  65
LEU A  14
 None
 1.09A 6czmA-5fydA:
undetectable
6czmC-5fydA:
undetectable		 6czmA-5fydA:
20.49
6czmC-5fydA:
20.49