SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 5g0f HDAC6
(Danio
rerio) 		4 / 5 VAL A1056
CYH A1049
ALA A1051
CYH A1052
 None
ZN  A2082 (-2.2A)
ZN  A2082 ( 4.3A)
ZN  A2082 (-2.4A)
 0.82A 1mz9D-5g0fA:
undetectable		 1mz9D-5g0fA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5g0f HDAC6
(Danio
rerio) 		3 / 3 PHE A1013
CYH A1011
HIS A1036
 None
ZN  A2083 (-2.3A)
ZN  A2083 (-3.2A)
 1.12A 3u9fS-5g0fA:
undetectable		 3u9fS-5g0fA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 5g0f HDAC6
(Danio
rerio) 		4 / 7 LEU A1018
VAL A1017
PRO A 998
GLU A1001
 None
 1.12A 4lb2A-5g0fA:
undetectable		 4lb2A-5g0fA:
11.09