SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		4 / 8 ILE A 271
GLY A 233
MET A 203
ILE A 223
 None
 0.94A 2qwxA-5g1dA:
undetectable
2qwxB-5g1dA:
undetectable		 2qwxA-5g1dA:
20.92
2qwxB-5g1dA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.06A 3nt1A-5g1dA:
undetectable		 3nt1A-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.05A 3nt1B-5g1dA:
undetectable		 3nt1B-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.18A 4rrwA-5g1dA:
undetectable		 4rrwA-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.19A 4rrwB-5g1dA:
undetectable		 4rrwB-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.11A 4rrxA-5g1dA:
undetectable		 4rrxA-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.10A 4rrxB-5g1dA:
undetectable		 4rrxB-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.18A 4rrzA-5g1dA:
undetectable		 4rrzA-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.19A 4rrzB-5g1dA:
undetectable		 4rrzB-5g1dA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		5 / 12 LEU A 131
VAL A 143
GLY A 128
ALA A 149
LEU A 119
 None
 1.07A 5jvzA-5g1dA:
undetectable		 5jvzA-5g1dA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5g1d SYNTENIN-1
(Rattus
norvegicus) 		3 / 3 THR A 268
MET A 203
HIS A 204
 None
 0.92A 5uunA-5g1dA:
undetectable		 5uunA-5g1dA:
22.22