SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g1n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5g1n CAD PROTEIN
(Homo
sapiens) 		5 / 12 LEU A2067
ALA A2056
VAL A2141
MET A1937
TYR A2097
 None
 1.34A 1kt4A-5g1nA:
undetectable		 1kt4A-5g1nA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 5g1n CAD PROTEIN
(Homo
sapiens) 		5 / 12 LEU A2142
VAL A2078
ARG A2200
ALA A2135
ALA A2175
 None
 1.24A 4fiaA-5g1nA:
undetectable		 4fiaA-5g1nA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5g1n CAD PROTEIN
(Homo
sapiens) 		5 / 12 LEU A2142
VAL A2078
ARG A2200
ALA A2135
ALA A2175
 None
 1.24A 4fiaA-5g1nA:
undetectable		 4fiaA-5g1nA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5g1n CAD PROTEIN
(Homo
sapiens) 		4 / 8 SER A1977
THR A2054
MET A2211
GLY A2210
 None
 0.91A 4fo4A-5g1nA:
undetectable		 4fo4A-5g1nA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 5g1n CAD PROTEIN
(Homo
sapiens) 		5 / 11 ALA A2091
GLY A2084
THR A2145
ASP A2059
LEU A2058
 None
 1.13A 5lf7V-5g1nA:
undetectable
5lf7W-5g1nA:
undetectable		 5lf7V-5g1nA:
21.01
5lf7W-5g1nA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g1n CAD PROTEIN
(Homo
sapiens) 		4 / 5 TYR A2143
MET A2077
THR A2076
LEU A2101
 None
 1.30A 5x1bJ-5g1nA:
undetectable		 5x1bJ-5g1nA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5g1n CAD PROTEIN
(Homo
sapiens) 		4 / 5 TYR A2143
MET A2077
THR A2076
LEU A2101
 None
 1.28A 5x1fW-5g1nA:
undetectable		 5x1fW-5g1nA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5g1n CAD PROTEIN
(Homo
sapiens) 		4 / 7 ILE A2132
LEU A2167
ILE A2075
ALA A2201
 None
 0.85A 6b5vA-5g1nA:
undetectable
6b5vC-5g1nA:
undetectable		 6b5vA-5g1nA:
14.06
6b5vC-5g1nA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5g1n CAD PROTEIN
(Homo
sapiens) 		4 / 7 ILE A2132
LEU A2167
ILE A2075
ALA A2201
 None
 0.86A 6b5vC-5g1nA:
undetectable
6b5vD-5g1nA:
undetectable		 6b5vC-5g1nA:
14.06
6b5vD-5g1nA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5g1n CAD PROTEIN
(Homo
sapiens) 		4 / 7 ALA A2201
ILE A2132
LEU A2167
ILE A2075
 None
 0.85A 6b5vB-5g1nA:
undetectable
6b5vD-5g1nA:
undetectable		 6b5vB-5g1nA:
14.06
6b5vD-5g1nA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 5g1n CAD PROTEIN
(Homo
sapiens) 		5 / 9 LEU A2067
MET A2073
VAL A2141
LEU A2094
ILE A2075
 None
 1.27A 6fdyU-5g1nA:
undetectable		 6fdyU-5g1nA:
22.74