SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
3 / 3 PHE A 193
TYR A 179
PRO A 195
None
1.01A 1mcnA-5g23A:
undetectable
1mcnB-5g23A:
undetectable
1mcnP-5g23A:
undetectable
1mcnA-5g23A:
23.51
1mcnB-5g23A:
23.51
1mcnP-5g23A:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
4 / 7 LEU A 178
VAL A 229
THR A 231
VAL A  63
None
0.90A 2zaxA-5g23A:
undetectable
2zaxA-5g23A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
4 / 5 GLN A  84
THR A 107
THR A 231
LEU A 178
None
1.38A 2zj0A-5g23A:
undetectable
2zj0A-5g23A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
3 / 3 LEU A  67
VAL A 173
ARG A 236
None
0.88A 3b0wB-5g23A:
undetectable
3b0wB-5g23A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
4 / 7 LEU A 178
VAL A 229
THR A 231
VAL A  63
None
0.91A 3fwgB-5g23A:
undetectable
3fwgB-5g23A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
4 / 7 LEU A 178
VAL A 229
THR A 231
VAL A  63
None
0.95A 3fwiA-5g23A:
undetectable
3fwiA-5g23A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
3 / 3 GLN A 230
THR A 231
LEU A 205
None
0.53A 3ondA-5g23A:
undetectable
3ondA-5g23A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
3 / 3 GLN A 230
THR A 231
LEU A 205
None
0.54A 3ondB-5g23A:
undetectable
3ondB-5g23A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
5 / 11 LEU A 205
VAL A 147
LEU A 178
LEU A 209
LEU A 226
None
1.09A 4or0B-5g23A:
undetectable
4or0B-5g23A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZP0_A_DXCA500_0
(MULTIDRUG
TRANSPORTER MDFA)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
5 / 10 ASP A  81
LEU A 205
PRO A  76
LEU A 209
GLY A 153
None
1.14A 4zp0A-5g23A:
undetectable
4zp0A-5g23A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
5 / 12 SER A  75
GLY A  85
GLY A 108
VAL A  73
LEU A  72
None
1.21A 5kocB-5g23A:
undetectable
5kocB-5g23A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
4 / 8 TRP A 155
THR A 154
TYR A 149
LEU A 209
None
1.39A 5kxiD-5g23A:
undetectable
5kxiE-5g23A:
undetectable
5kxiD-5g23A:
22.08
5kxiE-5g23A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)
5g23 TYPE-IV LIKE PILIN
TTHA1219

(Thermus
thermophilus)
4 / 4 GLN A  84
THR A 107
THR A 231
LEU A 178
None
1.45A 6f3mB-5g23A:
undetectable
6f3mB-5g23A:
21.00