SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 8 TYR A 350
GLY A 371
LEU A 360
PHE A 330
 None
None
None
97N  A1451 ( 4.8A)
 1.22A 1gsfA-5g26A:
undetectable		 1gsfA-5g26A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 8 TYR A 350
GLY A 371
LEU A 360
PHE A 330
 None
None
None
97N  A1451 ( 4.8A)
 1.22A 1gsfB-5g26A:
undetectable		 1gsfB-5g26A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 8 TYR A 350
GLY A 371
LEU A 360
PHE A 330
 None
None
None
97N  A1451 ( 4.8A)
 1.22A 1gsfD-5g26A:
undetectable		 1gsfD-5g26A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5g26 INTIMIN
(Escherichia
coli) 		5 / 12 LEU A 430
LEU A 427
GLN A 410
MET A 271
LEU A 241
 None
 1.42A 2oaxA-5g26A:
undetectable		 2oaxA-5g26A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_A_PRLA1188_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 8 HIS A 314
SER A 311
ASP A 281
ARG A 254
 None
 0.95A 2v57A-5g26A:
undetectable		 2v57A-5g26A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V57_C_PRLC1187_0
(TETR FAMILY
TRANSCRIPTIONAL
REPRESSOR LFRR)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 8 HIS A 314
SER A 311
ASP A 281
ARG A 254
 None
 0.94A 2v57C-5g26A:
undetectable		 2v57C-5g26A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 5 GLN A 406
PHE A 407
LEU A 228
PHE A 230
 None
None
None
97M  A1452 ( 3.7A)
 1.40A 3ablC-5g26A:
undetectable
3ablJ-5g26A:
undetectable		 3ablC-5g26A:
21.75
3ablJ-5g26A:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 5g26 INTIMIN
(Escherichia
coli) 		3 / 3 ASN A 221
ASN A 362
GLU A 398
 None
 0.93A 3kpdB-5g26A:
undetectable		 3kpdB-5g26A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 5g26 INTIMIN
(Escherichia
coli) 		3 / 3 ARG A 333
ASP A 400
GLN A 367
 None
 0.72A 3lcvB-5g26A:
undetectable		 3lcvB-5g26A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 5g26 INTIMIN
(Escherichia
coli) 		3 / 3 ARG A 333
ARG A 440
ILE A 349
 None
 0.84A 4b7qC-5g26A:
undetectable		 4b7qC-5g26A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 5 LEU A 338
ALA A 346
LEU A 344
VAL A 375
 None
 0.90A 5cr1A-5g26A:
undetectable		 5cr1A-5g26A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5g26 INTIMIN
(Escherichia
coli) 		4 / 6 ASP A 229
ASP A 390
ASN A 378
GLN A 439
 None
 1.27A 5l6eA-5g26A:
undetectable		 5l6eA-5g26A:
22.68