SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5g2h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T03_P_TFOP822_1 (POL POLYPROTEIN SYNTHETIC OLIGONUCLEOTIDE PRIMER)	5g2h	- (Salmonella enterica)	4 / 7	ASP A 207 ASP A 210 ASP A 209 LYS A 232	None None CME A 241 ( 4.2A) None	1.04A	1t03A-5g2hA: undetectable	1t03A-5g2hA: 17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y05_A_RALA801_1 (PROSTAGLANDIN REDUCTASE 1)	5g2h	- (Salmonella enterica)	4 / 8	ARG A 169 VAL A 190 TYR A 194 VAL A 168	None	1.19A	2y05A-5g2hA: undetectable 2y05B-5g2hA: 2.3	2y05A-5g2hA: 23.24 2y05B-5g2hA: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D4U_D_SAMD301_0 (UNCHARACTERIZED PROTEIN MJ0489)	5g2h	- (Salmonella enterica)	5 / 12	GLY A 225 ILE A 223 HIS A 47 GLY A 203 ILE A 205	SO4 A1245 (-3.4A) None None SO4 A1245 ( 3.9A) None	0.99A	5d4uD-5g2hA: undetectable	5d4uD-5g2hA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5K9D_A_ACTA405_0 (DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL)	5g2h	- (Salmonella enterica)	3 / 3	GLN A 61 THR A 52 ASP A 10	None	0.81A	5k9dA-5g2hA: 7.3	5k9dA-5g2hA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GB9_A_ACTA508_0 (MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1)	5g2h	- (Salmonella enterica)	3 / 3	VAL A 100 ALA A 127 GLN A 77	None	0.63A	6gb9A-5g2hA: undetectable	6gb9A-5g2hA: 22.17

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1T03_P_TFOP822_1","POL POLYPROTEIN;SYNTHETIC OLIGONUCLEOTIDE PRIMER","5g2h","-","Salmonella enterica",4,"ASP A 207;ASP A 210;ASP A 209;LYS A 232","None;None;CME A 241 ( 4.2A);None","1.04A","1t03A-5g2hA:undetectable","1t03A-5g2hA:17.73"],["2Y05_A_RALA801_1","PROSTAGLANDIN REDUCTASE 1;PROSTAGLANDIN REDUCTASE 1","5g2h","-","Salmonella enterica",4,"ARG A 169;VAL A 190;TYR A 194;VAL A 168","None","1.19A","2y05A-5g2hA:undetectable;2y05B-5g2hA:2.3","2y05A-5g2hA:23.24;2y05B-5g2hA:23.24"],["5D4U_D_SAMD301_0","UNCHARACTERIZED PROTEIN MJ0489","5g2h","-","Salmonella enterica",5,"GLY A 225;ILE A 223;HIS A  47;GLY A 203;ILE A 205","SO4 A1245 (-3.4A);None;None;SO4 A1245 ( 3.9A);None","0.99A","5d4uD-5g2hA:undetectable","5d4uD-5g2hA:21.16"],["5K9D_A_ACTA405_0","DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL","5g2h","-","Salmonella enterica",3,"GLN A  61;THR A  52;ASP A  10","None","0.81A","5k9dA-5g2hA:7.3","5k9dA-5g2hA:23.38"],["6GB9_A_ACTA508_0","MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1","5g2h","-","Salmonella enterica",3,"VAL A 100;ALA A 127;GLN A  77","None","0.63A","6gb9A-5g2hA:undetectable","6gb9A-5g2hA:22.17"]]